STRINGSTRING
chek2 chek2 supt16h supt16h ENSEEEP00000001009 ENSEEEP00000001009 LOC113578294 LOC113578294 rmi2 rmi2 rpa1 rpa1 cdk5 cdk5 ENSEEEP00000001628 ENSEEEP00000001628 LOC113570831 LOC113570831 ENSEEEP00000002053 ENSEEEP00000002053 LOC113588727 LOC113588727 exd2 exd2 LOC113575357 LOC113575357 rfc4 rfc4 LOC113570321 LOC113570321 rmi1 rmi1 tp53rk tp53rk LOC113584288 LOC113584288 LOC113588781 LOC113588781 prkag1 prkag1 tbp tbp LOC113569058 LOC113569058 ENSEEEP00000006026 ENSEEEP00000006026 ENSEEEP00000006028 ENSEEEP00000006028 tdrd3 tdrd3 LOC113587227 LOC113587227 ENSEEEP00000006788 ENSEEEP00000006788 ssrp1 ssrp1 LOC113570838 LOC113570838 ENSEEEP00000007003 ENSEEEP00000007003 PRKAB2 PRKAB2 chek1 chek1 tbpl2 tbpl2 DNA2 DNA2 rps27a rps27a plk3 plk3 cdca7 cdca7 tpx2 tpx2 rfc2 rfc2 nbn nbn top3a top3a cdca7l cdca7l recql4 recql4 LOC113591174 LOC113591174 LOC113592136 LOC113592136 ccna1 ccna1 ENSEEEP00000012726 ENSEEEP00000012726 ENSEEEP00000012727 ENSEEEP00000012727 ENSEEEP00000013350 ENSEEEP00000013350 taf12 taf12 rad50 rad50 tbpl1 tbpl1 LOC113585541 LOC113585541 LOC113585539 LOC113585539 LOC113586687 LOC113586687 taf6 taf6 LOC113573808 LOC113573808 topbp1 topbp1 dyrk4 dyrk4 LOC113590096 LOC113590096 taf13 taf13 ENSEEEP00000016182 ENSEEEP00000016182 atrip atrip rad1 rad1 mdm2 mdm2 LOC113576377 LOC113576377 LOC113578113 LOC113578113 rhno1 rhno1 ENSEEEP00000050947 ENSEEEP00000050947 ENSEEEP00000050839 ENSEEEP00000050839 LOC113584832 LOC113584832 stk11 stk11 tp53inp1 tp53inp1 uba52 uba52 ankrd12 ankrd12 LOC113585558 LOC113585558 ENSEEEP00000017959 ENSEEEP00000017959 cdk2 cdk2 ENSEEEP00000018543 ENSEEEP00000018543 csnk2b csnk2b exo1 exo1 LOC113570062 LOC113570062 rfc5 rfc5 taf11 taf11 rfc3 rfc3 ENSEEEP00000023290 ENSEEEP00000023290 LOC113585673 LOC113585673 taf2 taf2 rpa3 rpa3 mre11 mre11 tp53inp2 tp53inp2 LOC113577231 LOC113577231 LOC113584577 LOC113584577 taf10 taf10 LOC113568139 LOC113568139 pin1 pin1 slf1 slf1 noc2l noc2l prkaa1 prkaa1 LOC113589633 LOC113589633 ENSEEEP00000031800 ENSEEEP00000031800 rad9a rad9a LOC113570719 LOC113570719 taf3 taf3 ENSEEEP00000032310 ENSEEEP00000032310 ccna2 ccna2 LOC113572423 LOC113572423 ENSEEEP00000033138 ENSEEEP00000033138 atr atr tp53 tp53 rbbp8 rbbp8 csnk2a2 csnk2a2 blm blm LOC113579649 LOC113579649 rad17 rad17 LOC113571217 LOC113571217 dyrk2 dyrk2 nuak1 nuak1 ENSEEEP00000037921 ENSEEEP00000037921 LOC113579159 LOC113579159 mdm4 mdm4 LOC113578530 LOC113578530 ankrd11 ankrd11 LOC113574050 LOC113574050 LOC113577352 LOC113577352 taf5 taf5 hus1 hus1 rpa2 rpa2 LOC113584157 LOC113584157 LOC113571278 LOC113571278 taf7 taf7 ENSEEEP00000046546 ENSEEEP00000046546 prkaa2 prkaa2 kxd1 kxd1 mapkapk5 mapkapk5 LOC113576847 LOC113576847
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chek2Uncharacterized protein. (526 aa)
supt16hUncharacterized protein. (1064 aa)
ENSEEEP00000001009Uncharacterized protein. (279 aa)
LOC113578294Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (427 aa)
rmi2Uncharacterized protein. (147 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (624 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (294 aa)
ENSEEEP00000001628Uncharacterized protein. (197 aa)
LOC113570831Protein kinase domain-containing protein. (1260 aa)
ENSEEEP00000002053TAF4 domain-containing protein. (282 aa)
LOC113588727Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
exd2Exonuclease 3'-5' domain containing 2. (616 aa)
LOC113575357Mitogen-activated protein kinase. (351 aa)
rfc4AAA domain-containing protein. (357 aa)
LOC113570321Homeodomain interacting protein kinase 1a. (1113 aa)
rmi1DUF1767 domain-containing protein. (587 aa)
tp53rkProtein kinase domain-containing protein. (168 aa)
LOC113584288TAFH domain-containing protein. (877 aa)
LOC113588781Cyclin-dependent kinase 5 activator. (326 aa)
prkag1Uncharacterized protein. (420 aa)
tbpUncharacterized protein. (297 aa)
LOC113569058AAA_23 domain-containing protein. (469 aa)
ENSEEEP00000006026Protein kinase domain-containing protein. (70 aa)
ENSEEEP00000006028Protein kinase domain-containing protein. (154 aa)
tdrd3Uncharacterized protein. (790 aa)
LOC113587227Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (307 aa)
ENSEEEP00000006788Uncharacterized protein. (339 aa)
ssrp1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (698 aa)
LOC113570838Homeodomain interacting protein kinase 2. (1184 aa)
ENSEEEP00000007003AAA_23 domain-containing protein. (53 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (257 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (470 aa)
tbpl2Uncharacterized protein. (311 aa)
DNA2DNA replication helicase/nuclease 2. (1002 aa)
rps27aUbiquitin-like domain-containing protein. (156 aa)
plk3Serine/threonine-protein kinase PLK. (662 aa)
cdca7zf-4CXXC_R1 domain-containing protein. (406 aa)
tpx2Uncharacterized protein. (724 aa)
rfc2AAA domain-containing protein. (369 aa)
nbnNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (816 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1009 aa)
cdca7lCell division cycle associated 7b. (425 aa)
recql4RecQ helicase-like 4. (817 aa)
LOC113591174Uncharacterized protein. (304 aa)
LOC113592136TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1705 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (322 aa)
ENSEEEP00000012726SWIB domain-containing protein. (118 aa)
ENSEEEP00000012727Uncharacterized protein. (97 aa)
ENSEEEP00000013350Uncharacterized protein. (106 aa)
taf12TFIID_20kDa domain-containing protein. (162 aa)
rad50RAD50 homolog, double strand break repair protein. (1181 aa)
tbpl1Uncharacterized protein. (186 aa)
LOC113585541Mitogen-activated protein kinase. (395 aa)
LOC113585539Protein kinase domain-containing protein. (1106 aa)
LOC113586687Homeodomain interacting protein kinase 3a. (1194 aa)
taf6TAF domain-containing protein. (652 aa)
LOC113573808Protein kinase, AMP-activated, gamma 2 non-catalytic subunit a. (500 aa)
topbp1DNA topoisomerase II binding protein 1. (1479 aa)
dyrk4Protein kinase domain-containing protein. (644 aa)
LOC113590096Mitogen-activated protein kinase. (389 aa)
taf13Uncharacterized protein. (124 aa)
ENSEEEP00000016182Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (174 aa)
atripATR interacting protein. (763 aa)
rad1Uncharacterized protein. (279 aa)
mdm2Uncharacterized protein. (512 aa)
LOC113576377Mitogen-activated protein kinase. (359 aa)
LOC113578113Protein kinase domain-containing protein. (627 aa)
rhno1Uncharacterized protein. (308 aa)
ENSEEEP00000050947Cyclin-dependent kinase 5 activator. (315 aa)
ENSEEEP00000050839Metallophos domain-containing protein. (106 aa)
LOC113584832AMPKBI domain-containing protein. (259 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (444 aa)
tp53inp1Uncharacterized protein. (240 aa)
uba52Ubiquitin-like domain-containing protein. (128 aa)
ankrd12ANK_REP_REGION domain-containing protein. (419 aa)
LOC113585558Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (326 aa)
ENSEEEP00000017959ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (784 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (324 aa)
ENSEEEP00000018543Methionine sulfoxide reductase B1b. (259 aa)
csnk2bCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (228 aa)
exo1Exonuclease 1. (771 aa)
LOC113570062Uncharacterized protein. (554 aa)
rfc5AAA domain-containing protein. (363 aa)
taf11TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (207 aa)
rfc3AAA domain-containing protein. (356 aa)
ENSEEEP00000023290RAD9 checkpoint clamp component B. (181 aa)
LOC113585673TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor. (517 aa)
taf2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1155 aa)
rpa3Uncharacterized protein. (122 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa)
tp53inp2Uncharacterized protein. (295 aa)
LOC113577231RPA_C domain-containing protein. (232 aa)
LOC113584577Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
taf10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (191 aa)
LOC113568139AMPKBI domain-containing protein. (268 aa)
pin1Peptidyl-prolyl cis-trans isomerase. (196 aa)
slf1ANK_REP_REGION domain-containing protein. (905 aa)
noc2lUncharacterized protein. (821 aa)
prkaa1Non-specific serine/threonine protein kinase. (574 aa)
LOC113589633Cyclin-dependent kinase 5 activator. (304 aa)
ENSEEEP00000031800NUAK family, SNF1-like kinase, 2. (604 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (386 aa)
LOC113570719FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (717 aa)
taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (774 aa)
ENSEEEP00000032310ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3024 aa)
ccna2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (428 aa)
LOC113572423Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (399 aa)
ENSEEEP00000033138Uncharacterized protein. (99 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2627 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (370 aa)
rbbp8SAE2 domain-containing protein. (131 aa)
csnk2a2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (363 aa)
blmBLM RecQ like helicase. (1281 aa)
LOC113579649TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (548 aa)
rad17Uncharacterized protein. (683 aa)
LOC113571217Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (390 aa)
dyrk2Protein kinase domain-containing protein. (587 aa)
nuak1Protein kinase domain-containing protein. (638 aa)
ENSEEEP00000037921Uncharacterized protein. (58 aa)
LOC113579159Dual specificity tyrosine phosphorylation regulated kinase 3. (557 aa)
mdm4MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. (445 aa)
LOC113578530Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (308 aa)
ankrd11ANK_REP_REGION domain-containing protein. (2837 aa)
LOC113574050Cyclin-dependent kinase 5 activator. (308 aa)
LOC113577352Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (366 aa)
taf5Uncharacterized protein. (742 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (283 aa)
rpa2RPA_C domain-containing protein. (280 aa)
LOC113584157Ubiquitin-like domain-containing protein. (77 aa)
LOC113571278Uncharacterized protein. (248 aa)
taf7TAFII55_N domain-containing protein. (377 aa)
ENSEEEP00000046546TAF4 domain-containing protein. (277 aa)
prkaa2Non-specific serine/threonine protein kinase. (552 aa)
kxd1KxDL domain-containing protein. (183 aa)
mapkapk5Protein kinase domain-containing protein. (471 aa)
LOC113576847RING-type domain-containing protein. (995 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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