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rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (624 aa) | ||||
brip1 | Helicase ATP-binding domain-containing protein. (1220 aa) | ||||
pold1 | DNA polymerase. (1061 aa) | ||||
LOC113568250 | RAD51 paralog C. (260 aa) | ||||
pold3 | Uncharacterized protein. (462 aa) | ||||
pold4 | Uncharacterized protein. (109 aa) | ||||
rad51d | RECA_2 domain-containing protein. (338 aa) | ||||
nbn | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (816 aa) | ||||
top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1009 aa) | ||||
babam2 | Uncharacterized protein. (442 aa) | ||||
rad54l | RAD54 like. (741 aa) | ||||
rad50 | RAD50 homolog, double strand break repair protein. (1181 aa) | ||||
xrcc3 | RECA_2 domain-containing protein. (355 aa) | ||||
rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) | ||||
rpa3 | Uncharacterized protein. (122 aa) | ||||
babam1 | Uncharacterized protein. (359 aa) | ||||
ENSEEEP00000032310 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3024 aa) | ||||
rbbp8 | SAE2 domain-containing protein. (131 aa) | ||||
XRCC2 | RECA_2 domain-containing protein. (302 aa) | ||||
pold2 | Uncharacterized protein. (469 aa) | ||||
mus81 | MUS81 structure-specific endonuclease subunit. (615 aa) | ||||
rad54b | RAD54 homolog B. (847 aa) | ||||
ssbp1 | Uncharacterized protein. (149 aa) | ||||
brcc3 | BRCA1/BRCA2-containing complex, subunit 3. (269 aa) | ||||
uimc1 | RAP80_UIM domain-containing protein. (953 aa) | ||||
rpa2 | RPA_C domain-containing protein. (280 aa) | ||||
sycp3 | Synaptonemal complex protein 3. (235 aa) | ||||
rad52 | RAD52 homolog, DNA repair protein. (287 aa) | ||||
sem1 | Uncharacterized protein. (70 aa) | ||||
eme1 | Essential meiotic structure-specific endonuclease 1. (550 aa) |