STRINGSTRING
ppm1d ppm1d LOC113578191 LOC113578191 cdk1 cdk1 rchy1 rchy1 LOC113586537 LOC113586537 LOC113589335 LOC113589335 LOC113587140 LOC113587140 pidd1 pidd1 ccng2 ccng2 Cop1 Cop1 gorab gorab ENSEEEP00000012726 ENSEEEP00000012726 LOC113579862 LOC113579862 ENSEEEP00000013818 ENSEEEP00000013818 LOC113578872 LOC113578872 ccnd2 ccnd2 shisa5 shisa5 ENSEEEP00000017695 ENSEEEP00000017695 perp perp bcl2 bcl2 ccnb1 ccnb1 rrm2 rrm2 pten pten ei24 ei24 LOC113576608 LOC113576608 ddb2 ddb2 sesn1 sesn1 serpine1 serpine1 LOC113590807 LOC113590807 rprm rprm LOC113588302 LOC113588302 ccne1 ccne1 ENSEEEP00000027296 ENSEEEP00000027296 igf1 igf1 LOC113585774 LOC113585774 LOC113575046 LOC113575046 cdkn1a cdkn1a ENSEEEP00000032310 ENSEEEP00000032310 cdk4 cdk4 atr atr casp3 casp3 LOC113580268 LOC113580268 bcl2l1 bcl2l1 ccnb2 ccnb2 ccnd1 ccnd1 LOC113578802 LOC113578802 mdm4 mdm4 LOC113579212 LOC113579212 cd82 cd82 LOC113590406 LOC113590406 LOC113577352 LOC113577352 LOC113588422 LOC113588422 gadd45g gadd45g cdk6 cdk6 LOC113573558 LOC113573558 LOC113573581 LOC113573581 gtse1 gtse1 siva1 siva1 LOC113571350 LOC113571350 LOC113582741 LOC113582741 CCNE2 CCNE2 chek2 chek2 ccng1 ccng1 ccne2 ccne2 zmat3 zmat3 LOC113578084 LOC113578084 gadd45b gadd45b IGFBP3 IGFBP3 mdm2 mdm2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ppm1dProtein phosphatase, Mg2+/Mn2+ dependent, 1Da. (536 aa)
LOC113578191Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (639 aa)
cdk1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
rchy1Uncharacterized protein. (273 aa)
LOC113586537Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (275 aa)
LOC113589335Ribosomal_L7Ae domain-containing protein. (159 aa)
LOC113587140Uncharacterized protein; Belongs to the cyclin family. (304 aa)
pidd1P53-induced death domain protein 1. (904 aa)
ccng2CYCLIN domain-containing protein; Belongs to the cyclin family. (333 aa)
Cop1COP1, E3 ubiquitin ligase. (430 aa)
gorabUncharacterized protein. (326 aa)
ENSEEEP00000012726SWIB domain-containing protein. (118 aa)
LOC113579862Ribosomal_L7Ae domain-containing protein. (158 aa)
ENSEEEP00000013818Ribosomal_L7Ae domain-containing protein. (154 aa)
LOC113578872Ribosomal_L7Ae domain-containing protein. (154 aa)
ccnd2Cyclin D2, a; Belongs to the cyclin family. (331 aa)
shisa5Uncharacterized protein. (239 aa)
ENSEEEP00000017695CYCLIN domain-containing protein; Belongs to the cyclin family. (182 aa)
perpUncharacterized protein. (185 aa)
bcl2BH4_2 domain-containing protein. (223 aa)
ccnb1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (396 aa)
rrm2Ribonucleotide reductase M2 polypeptide. (386 aa)
ptenPhosphatase and tensin homolog B. (484 aa)
ei24Uncharacterized protein. (345 aa)
LOC113576608Tetraspanin. (256 aa)
ddb2WD_REPEATS_REGION domain-containing protein. (485 aa)
sesn1Uncharacterized protein. (485 aa)
serpine1SERPIN domain-containing protein; Belongs to the serpin family. (410 aa)
LOC113590807Ribosomal_L7Ae domain-containing protein. (160 aa)
rprmUncharacterized protein. (103 aa)
LOC113588302Uncharacterized protein; Belongs to the peptidase C14A family. (371 aa)
ccne1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (410 aa)
ENSEEEP00000027296Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily. (186 aa)
igf1Insulin-like growth factor 1. (181 aa)
LOC113585774E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (307 aa)
LOC113575046Uncharacterized protein. (387 aa)
cdkn1aUncharacterized protein. (166 aa)
ENSEEEP00000032310ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3024 aa)
cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (292 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2627 aa)
casp3Uncharacterized protein; Belongs to the peptidase C14A family. (317 aa)
LOC113580268Uncharacterized protein. (206 aa)
bcl2l1BH4_2 domain-containing protein. (233 aa)
ccnb2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (382 aa)
ccnd1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
LOC113578802Uncharacterized protein. (204 aa)
mdm4MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. (445 aa)
LOC113579212Si:zfos-80g12.1. (400 aa)
cd82Tetraspanin. (249 aa)
LOC113590406Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (464 aa)
LOC113577352Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (366 aa)
LOC113588422Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
gadd45gRibosomal_L7Ae domain-containing protein. (159 aa)
cdk6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (324 aa)
LOC113573558Uncharacterized protein. (174 aa)
LOC113573581Uncharacterized protein. (209 aa)
gtse1G-2 and S-phase expressed 1. (729 aa)
siva1Uncharacterized protein. (173 aa)
LOC113571350Thrombospondin 1a. (1160 aa)
LOC113582741Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (320 aa)
chek2Uncharacterized protein. (526 aa)
ccng1CYCLIN domain-containing protein; Belongs to the cyclin family. (299 aa)
ccne2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (394 aa)
zmat3Zinc finger, matrin-type 3. (318 aa)
LOC113578084Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (293 aa)
gadd45bRibosomal_L7Ae domain-containing protein. (162 aa)
IGFBP3Uncharacterized protein. (291 aa)
mdm2Uncharacterized protein. (512 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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