STRINGSTRING
fzd8 fzd8 Fzd10 Fzd10 Rnf43 Rnf43 axin1 axin1 LOC113578294 LOC113578294 dkk2 dkk2 LOC113580952 LOC113580952 ENSEEEP00000001362 ENSEEEP00000001362 LOC113587089 LOC113587089 LOC113588727 LOC113588727 dvl2 dvl2 LOC113579289 LOC113579289 LOC113584345 LOC113584345 LOC113580439 LOC113580439 LOC113572085 LOC113572085 LOC113578033 LOC113578033 LOC113569914 LOC113569914 wnt2b wnt2b LOC113587140 LOC113587140 ENSEEEP00000004531 ENSEEEP00000004531 dkk1 dkk1 wnt3a wnt3a LOC113587179 LOC113587179 LOC113587180 LOC113587180 sfrp5 sfrp5 lgr4 lgr4 LOC113574265 LOC113574265 Cxxc4 Cxxc4 ENSEEEP00000006813 ENSEEEP00000006813 LOC113574264 LOC113574264 LOC113590515 LOC113590515 CTBP2 CTBP2 LOC113581577 LOC113581577 cacybp cacybp LOC113567826 LOC113567826 ryk ryk axin2 axin2 nfatc1 nfatc1 wnt6 wnt6 LOC113581029 LOC113581029 LOC113572134 LOC113572134 LOC113592140 LOC113592140 wnt4 wnt4 LOC113581100 LOC113581100 LOC113578891 LOC113578891 LOC113568429 LOC113568429 Ror1 Ror1 LOC113587285 LOC113587285 LOC113571665 LOC113571665 rspo1 rspo1 LOC113574764 LOC113574764 ccnd2 ccnd2 LOC113573843 LOC113573843 LOC113587328 LOC113587328 ENSEEEP00000016367 ENSEEEP00000016367 LOC113578914 LOC113578914 LOC113572295 LOC113572295 LOC113572343 LOC113572343 LOC113580660 LOC113580660 znrf3 znrf3 ENSEEEP00000017695 ENSEEEP00000017695 ruvbl1 ruvbl1 ENSEEEP00000018248 ENSEEEP00000018248 wnt7a wnt7a Lef1 Lef1 csnk2b csnk2b Wnt10b Wnt10b wnt1 wnt1 LOC113572657 LOC113572657 smad4 smad4 LOC113589416 LOC113589416 LOC113585629 LOC113585629 Nkd2 Nkd2 fzd7 fzd7 LOC113574809 LOC113574809 cby1 cby1 LOC113591278 LOC113591278 LGR6 LGR6 sost sost LOC113591705 LOC113591705 ENSEEEP00000024503 ENSEEEP00000024503 LOC113592285 LOC113592285 ppard ppard apc apc LOC113581708 LOC113581708 Nfatc4 Nfatc4 LOC113571116 LOC113571116 LOC113570138 LOC113570138 LOC113581750 LOC113581750 LOC113584605 LOC113584605 ENSEEEP00000030422 ENSEEEP00000030422 LOC113575584 LOC113575584 LOC113585774 LOC113585774 fzd6 fzd6 LOC113570725 LOC113570725 LOC113587857 LOC113587857 LOC113584625 LOC113584625 LOC113571196 LOC113571196 fzd2 fzd2 LOC113572423 LOC113572423 lrp6 lrp6 rspo2 rspo2 LOC113572468 LOC113572468 mapk10 mapk10 MAPK10 MAPK10 wnt3 wnt3 csnk2a2 csnk2a2 LOC113586321 LOC113586321 LOC113579658 LOC113579658 ccn4 ccn4 LOC113571217 LOC113571217 LOC113580901 LOC113580901 LOC113589106 LOC113589106 LOC113567556 LOC113567556 ccnd1 ccnd1 LOC113571260 LOC113571260 ENSEEEP00000040145 ENSEEEP00000040145 LOC113577873 LOC113577873 LOC113578539 LOC113578539 LOC113589205 LOC113589205 serpinf1 serpinf1 LOC113578590 LOC113578590 LOC113578570 LOC113578570 PPP3CA PPP3CA ENSEEEP00000041692 ENSEEEP00000041692 ror2 ror2 LOC113579220 LOC113579220 prickle1 prickle1 ENSEEEP00000042197 ENSEEEP00000042197 LOC113572862 LOC113572862 LOC113577352 LOC113577352 LOC113574086 LOC113574086 LOC113588422 LOC113588422 LOC113571960 LOC113571960 LOC113575836 LOC113575836 wnt16 wnt16 LOC113589257 LOC113589257 LOC113590921 LOC113590921 wnt2 wnt2 VANGL1 VANGL1 ENSEEEP00000046068 ENSEEEP00000046068 fzd4 fzd4 LOC113582761 LOC113582761 LOC113582750 LOC113582750 skp1 skp1 tcf7 tcf7 crebbp crebbp LOC113582797 LOC113582797 LOC113582834 LOC113582834 LOC113576821 LOC113576821 prkacb prkacb ctnnbip1 ctnnbip1 fzd9 fzd9 LOC113581283 LOC113581283 LOC113589820 LOC113589820 LOC113572206 LOC113572206 rock2 rock2 bambi bambi LOC113576905 LOC113576905 rbx1 rbx1 LOC113589826 LOC113589826 dvl3 dvl3 nfatc2 nfatc2 TBL1XR1 TBL1XR1 LOC113578084 LOC113578084 ENSEEEP00000051389 ENSEEEP00000051389 LOC113578089 LOC113578089 sfrp2 sfrp2 LOC113581434 LOC113581434 LOC113583078 LOC113583078 LOC113583072 LOC113583072 rspo3 rspo3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fzd8Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
Fzd10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (584 aa)
Rnf43RING-type domain-containing protein. (82 aa)
axin1Uncharacterized protein. (835 aa)
LOC113578294Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (427 aa)
dkk2Dickkopf_N domain-containing protein. (239 aa)
LOC113580952Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
ENSEEEP00000001362Axin 2 (conductin, axil). (322 aa)
LOC113587089Uncharacterized protein. (193 aa)
LOC113588727Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
dvl2Uncharacterized protein. (750 aa)
LOC113579289Uncharacterized protein. (449 aa)
LOC113584345CULLIN_2 domain-containing protein; Belongs to the cullin family. (777 aa)
LOC113580439Prickle homolog 2a. (820 aa)
LOC113572085Uncharacterized protein. (193 aa)
LOC113578033Mitogen-activated protein kinase. (447 aa)
LOC113569914Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (462 aa)
wnt2bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LOC113587140Uncharacterized protein; Belongs to the cyclin family. (304 aa)
ENSEEEP00000004531Protein kinase C, beta b. (195 aa)
dkk1Dickkopf_N domain-containing protein. (232 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
LOC113587179Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
LOC113587180Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
sfrp5Uncharacterized protein. (312 aa)
lgr4Leucine-rich repeat containing G protein-coupled receptor 4. (938 aa)
LOC113574265Mitogen-activated protein kinase. (446 aa)
Cxxc4CXXC finger 4. (223 aa)
ENSEEEP00000006813Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
LOC113574264Uncharacterized protein. (192 aa)
LOC113590515Uncharacterized protein. (533 aa)
CTBP2Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
LOC113581577Uncharacterized protein. (355 aa)
cacybpUncharacterized protein. (227 aa)
LOC113567826Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (579 aa)
rykUncharacterized protein. (599 aa)
axin2Uncharacterized protein. (815 aa)
nfatc1Nuclear factor of activated T cells 1. (887 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
LOC113581029Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family. (513 aa)
LOC113572134Dishevelled associated activator of morphogenesis 2. (1079 aa)
LOC113592140Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
LOC113581100Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (464 aa)
LOC113578891Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
LOC113568429Vang-like protein. (501 aa)
Ror1Protein kinase domain-containing protein. (216 aa)
LOC113587285Uncharacterized protein. (193 aa)
LOC113571665RHD domain-containing protein. (874 aa)
rspo1Uncharacterized protein. (264 aa)
LOC113574764Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
ccnd2Cyclin D2, a; Belongs to the cyclin family. (331 aa)
LOC113573843Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (401 aa)
LOC113587328Nuclear factor of activated T cells 3a. (1060 aa)
ENSEEEP00000016367ANK_REP_REGION domain-containing protein. (102 aa)
LOC113578914Uncharacterized protein. (726 aa)
LOC113572295Uncharacterized protein. (294 aa)
LOC113572343Serine/threonine-protein phosphatase. (511 aa)
LOC113580660Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (473 aa)
znrf3Zinc and ring finger 3. (797 aa)
ENSEEEP00000017695CYCLIN domain-containing protein; Belongs to the cyclin family. (182 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
ENSEEEP00000018248PH_14 domain-containing protein. (69 aa)
wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
Lef1Lymphoid enhancer-binding factor 1. (212 aa)
csnk2bCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (228 aa)
Wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (197 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
LOC1135726571-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1218 aa)
smad4Mothers against decapentaplegic homolog. (545 aa)
LOC113589416Catenin (cadherin-associated protein), delta 2b. (1205 aa)
LOC113585629Uncharacterized protein. (790 aa)
Nkd2Naked cuticle homolog 2a. (362 aa)
fzd7Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (546 aa)
LOC113574809Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (428 aa)
cby1Uncharacterized protein. (131 aa)
LOC113591278Uncharacterized protein; Belongs to the protein kinase superfamily. (371 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (936 aa)
sostCTCK domain-containing protein. (216 aa)
LOC113591705Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (418 aa)
ENSEEEP00000024503Uncharacterized protein. (120 aa)
LOC113592285Uncharacterized protein. (526 aa)
ppardUncharacterized protein. (410 aa)
apcAdenomatous polyposis coli. (2709 aa)
LOC113581708RHD domain-containing protein. (846 aa)
Nfatc4RHD domain-containing protein. (165 aa)
LOC113571116Dishevelled associated activator of morphogenesis 1a. (1077 aa)
LOC113570138Uncharacterized protein. (524 aa)
LOC113581750Serine/threonine-protein phosphatase. (508 aa)
LOC113584605Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (386 aa)
ENSEEEP00000030422Serine/threonine-protein phosphatase. (291 aa)
LOC113575584F-box and WD repeat domain containing 11a. (540 aa)
LOC113585774E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (307 aa)
fzd6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (652 aa)
LOC113570725Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (449 aa)
LOC113587857Uncharacterized protein; Belongs to the protein kinase superfamily. (379 aa)
LOC113584625Uncharacterized protein. (205 aa)
LOC113571196Mothers against decapentaplegic homolog. (572 aa)
fzd2Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
LOC113572423Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (399 aa)
lrp6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1633 aa)
rspo2Uncharacterized protein. (245 aa)
LOC113572468Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (440 aa)
mapk10Mitogen-activated protein kinase. (244 aa)
MAPK10Mitogen-activated protein kinase 10. (232 aa)
wnt3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
csnk2a2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (363 aa)
LOC113586321Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (440 aa)
LOC113579658Uncharacterized protein. (186 aa)
ccn4Uncharacterized protein. (368 aa)
LOC113571217Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (390 aa)
LOC113580901Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (754 aa)
LOC113589106BZIP domain-containing protein; Belongs to the bZIP family. (324 aa)
LOC113567556Uncharacterized protein. (790 aa)
ccnd1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
LOC113571260Mitogen-activated protein kinase. (426 aa)
ENSEEEP00000040145Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
LOC113577873BHLH domain-containing protein. (360 aa)
LOC113578539Frizzled class receptor 7a; Belongs to the G-protein coupled receptor Fz/Smo family. (545 aa)
LOC113589205Chromodomain helicase DNA binding protein 8. (1683 aa)
serpinf1SERPIN domain-containing protein; Belongs to the serpin family. (408 aa)
LOC113578590Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (685 aa)
LOC113578570Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (406 aa)
PPP3CASerine/threonine-protein phosphatase. (510 aa)
ENSEEEP00000041692Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
ror2Receptor tyrosine kinase-like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (915 aa)
LOC113579220Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (555 aa)
prickle1Prickle homolog 1a. (838 aa)
ENSEEEP00000042197RGS domain-containing protein. (277 aa)
LOC113572862Uncharacterized protein. (192 aa)
LOC113577352Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (366 aa)
LOC113574086Mothers against decapentaplegic homolog. (425 aa)
LOC113588422Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
LOC113571960Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (541 aa)
LOC113575836Uncharacterized protein. (193 aa)
wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
LOC113589257HMG box domain-containing protein. (547 aa)
LOC113590921Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
wnt2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
VANGL1Vang-like protein. (522 aa)
ENSEEEP00000046068Uncharacterized protein. (136 aa)
fzd4Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (530 aa)
LOC113582761Notum pectinacetylesterase 2. (456 aa)
LOC113582750SUMO specific peptidase 2. (482 aa)
skp1Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
tcf7Transcription factor 7. (429 aa)
crebbpCREB binding protein b. (2451 aa)
LOC113582797Uncharacterized protein. (193 aa)
LOC113582834BZIP domain-containing protein. (352 aa)
LOC113576821Uncharacterized protein. (505 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (395 aa)
ctnnbip1Catenin, beta interacting protein 1. (112 aa)
fzd9Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
LOC113581283Dishevelled segment polarity protein 1a. (709 aa)
LOC113589820Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (377 aa)
LOC113572206Uncharacterized protein. (155 aa)
rock2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1397 aa)
bambiUncharacterized protein. (267 aa)
LOC113576905Secreted frizzled-related protein 1a. (312 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (135 aa)
LOC113589826Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (454 aa)
dvl3Dishevelled segment polarity protein 3b. (508 aa)
nfatc2Nuclear factor of activated T cells 2a. (849 aa)
TBL1XR1WD_REPEATS_REGION domain-containing protein. (637 aa)
LOC113578084Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (293 aa)
ENSEEEP00000051389Adenomatosis polyposis coli 2. (2450 aa)
LOC113578089Uncharacterized protein. (854 aa)
sfrp2Uncharacterized protein. (291 aa)
LOC113581434Prickle homolog 2b. (807 aa)
LOC113583078Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa)
LOC113583072Uncharacterized protein. (198 aa)
rspo3R-spondin 3. (312 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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