(50 nodes) RIG-I-like receptor signaling pathway network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113573008	OTU deubiquitinase 5b. (462 aa)
	LOC113589567	SCY domain-containing protein. (95 aa)
	LOC113575357	Mitogen-activated protein kinase. (351 aa)
	LOC113575356	Mitogen-activated protein kinase. (364 aa)
	LOC113578033	Mitogen-activated protein kinase. (447 aa)
	traf3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
	ikbkb	Protein kinase domain-containing protein. (777 aa)
	LOC113574265	Mitogen-activated protein kinase. (446 aa)
	trim25	Uncharacterized protein. (731 aa)
	LOC113591502	Uncharacterized protein. (943 aa)
	LOC113580518	Si:dkey-88e18.2. (279 aa)
	LOC113590096	Mitogen-activated protein kinase. (389 aa)
	ddx3x	DEAD-box helicase 3 X-linked a; Belongs to the DEAD box helicase family. (696 aa)
	LOC113587340	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (100 aa)
	dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58. (673 aa)
	LOC113571703	ANK_REP_REGION domain-containing protein. (308 aa)
	ENSEEEP00000022670	Uncharacterized protein. (188 aa)
	LOC113588302	Uncharacterized protein; Belongs to the peptidase C14A family. (371 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	atg12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (122 aa)
	sting1	Uncharacterized protein. (420 aa)
	sike1	Uncharacterized protein. (213 aa)
	azi2	Uncharacterized protein. (378 aa)
	tbk1	Protein kinase domain-containing protein. (727 aa)
	mapk10	Mitogen-activated protein kinase. (244 aa)
	MAPK10	Mitogen-activated protein kinase 10. (232 aa)
	LOC113585165	SCY domain-containing protein. (99 aa)
	tradd	Death domain-containing protein. (293 aa)
	LOC113584194	V-rel avian reticuloendotheliosis viral oncogene homolog A. (633 aa)
	ikbkg	CCHC NOA-type domain-containing protein. (561 aa)
	LOC113579176	Protein kinase domain-containing protein. (712 aa)
	fadd	Uncharacterized protein. (190 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
	LOC113571260	Mitogen-activated protein kinase. (426 aa)
	LOC113590849	IRF tryptophan pentad repeat domain-containing protein. (476 aa)
	LOC113571296	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (289 aa)
	LOC113577947	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa)
	nfkb1	Uncharacterized protein. (952 aa)
	LOC113574035	Uncharacterized protein; Belongs to the peptidase C14A family. (369 aa)
	tkfc	Uncharacterized protein. (579 aa)
	LOC113588078	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (536 aa)
	LOC113582581	Uncharacterized protein; Belongs to the DEAD box helicase family. (720 aa)
	LOC113577382	Mitogen-activated protein kinase. (365 aa)
	irf7	IRF tryptophan pentad repeat domain-containing protein. (437 aa)
	cyld	Uncharacterized protein; Belongs to the peptidase C19 family. (964 aa)
	tank	TBD domain-containing protein. (343 aa)
	ifih1	Uncharacterized protein. (1010 aa)
	chuk	Protein kinase domain-containing protein. (778 aa)
	ripk1	Uncharacterized protein. (678 aa)
	LOC113576377	Mitogen-activated protein kinase. (359 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000022670	LOC113584194	ENSEEEP00000022670	ENSEEEP00000035430	Uncharacterized protein.	V-rel avian reticuloendotheliosis viral oncogene homolog A.	0.900
ENSEEEP00000022670	LOC113590849	ENSEEEP00000022670	ENSEEEP00000040166	Uncharacterized protein.	IRF tryptophan pentad repeat domain-containing protein.	0.920
ENSEEEP00000022670	irf7	ENSEEEP00000022670	ENSEEEP00000049167	Uncharacterized protein.	IRF tryptophan pentad repeat domain-containing protein.	0.912
ENSEEEP00000022670	nfkb1	ENSEEEP00000022670	ENSEEEP00000041172	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC113571260	LOC113574265	ENSEEEP00000040040	ENSEEEP00000006399	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.868
LOC113571260	LOC113578033	ENSEEEP00000040040	ENSEEEP00000003480	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.868
LOC113571260	MAPK10	ENSEEEP00000040040	ENSEEEP00000034774	Mitogen-activated protein kinase.	Mitogen-activated protein kinase 10.	0.866
LOC113571260	mapk10	ENSEEEP00000040040	ENSEEEP00000034640	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.868
LOC113571296	LOC113580518	ENSEEEP00000040688	ENSEEEP00000013908	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	Si:dkey-88e18.2.	0.911
LOC113571703	LOC113579176	ENSEEEP00000020925	ENSEEEP00000037972	ANK_REP_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.437
LOC113571703	LOC113584194	ENSEEEP00000020925	ENSEEEP00000035430	ANK_REP_REGION domain-containing protein.	V-rel avian reticuloendotheliosis viral oncogene homolog A.	0.979
LOC113571703	chuk	ENSEEEP00000020925	ENSEEEP00000050459	ANK_REP_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.967
LOC113571703	ikbkb	ENSEEEP00000020925	ENSEEEP00000005106	ANK_REP_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.993
LOC113571703	ikbkg	ENSEEEP00000020925	ENSEEEP00000037274	ANK_REP_REGION domain-containing protein.	CCHC NOA-type domain-containing protein.	0.991
LOC113571703	nfkb1	ENSEEEP00000020925	ENSEEEP00000041172	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.988
LOC113571703	tbk1	ENSEEEP00000020925	ENSEEEP00000033146	ANK_REP_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.437
LOC113571703	traf6	ENSEEEP00000020925	ENSEEEP00000039538	ANK_REP_REGION domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.718
LOC113573008	traf3	ENSEEEP00000000488	ENSEEEP00000004709	OTU deubiquitinase 5b.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.937
LOC113573008	traf6	ENSEEEP00000000488	ENSEEEP00000039538	OTU deubiquitinase 5b.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.401
LOC113574035	LOC113577947	ENSEEEP00000042103	ENSEEEP00000040785	Uncharacterized protein; Belongs to the peptidase C14A family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.633