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dusp4 dusp4 LOC105029346 LOC105029346 LOC105029391 LOC105029391 LOC105020225 LOC105020225 LOC105020226 LOC105020226 LOC105005941 LOC105005941 LOC105014063 LOC105014063 LOC105013860 LOC105013860 LOC105029097 LOC105029097 LOC105023646 LOC105023646 ENSELUP00000004609 ENSELUP00000004609 LOC105017320 LOC105017320 ENSELUP00000005325 ENSELUP00000005325 LOC105006773 LOC105006773 mapk15 mapk15 LOC105011734 LOC105011734 creb5 creb5 dusp3 dusp3 zfp36l1 zfp36l1 mapk8ip3 mapk8ip3 dusp16 dusp16 LOC105014839 LOC105014839 ptpn7 ptpn7 LOC105027407 LOC105027407 ENSELUP00000010466 ENSELUP00000010466 LOC105018531 LOC105018531 dusp6 dusp6 metrnl metrnl ptprr ptprr LOC105023872 LOC105023872 JUND JUND LOC105023081 LOC105023081 limk2 limk2 dusp10 dusp10 ENSELUP00000013778 ENSELUP00000013778 LOC105013205 LOC105013205 LOC105020506 LOC105020506 hsbp1 hsbp1 LOC105028071 LOC105028071 MEF2D MEF2D MAPK9 MAPK9 HSBP1 HSBP1 mef2c mef2c ENSELUP00000017121 ENSELUP00000017121 mob2 mob2 mapk4 mapk4 LOC105017017 LOC105017017 LOC105007426 LOC105007426 mapkapk5 mapkapk5 ENSELUP00000020561 ENSELUP00000020561 hsf5 hsf5 mapk6 mapk6 ENSELUP00000020820 ENSELUP00000020820 hspb1 hspb1 clic2 clic2 Mapk10 Mapk10 ENSELUP00000021764 ENSELUP00000021764 LOC105026854 LOC105026854 NR4A1 NR4A1 mapk8ip2 mapk8ip2 dusp5 dusp5 Hspb3 Hspb3 atf3 atf3 LOC105024911 LOC105024911 ENSELUP00000025951 ENSELUP00000025951 LOC114840870 LOC114840870 hspb2 hspb2 Jun Jun LOC105022309 LOC105022309 cfl2 cfl2 mapk7 mapk7 ENSELUP00000028193 ENSELUP00000028193 batf batf LOC105005940 LOC105005940 jkamp jkamp LOC105015210 LOC105015210 LOC105006595 LOC105006595 jdp2 jdp2 ENSELUP00000030208 ENSELUP00000030208 limk1 limk1 LOC105007365 LOC105007365 LOC105020581 LOC105020581 clic4-2 clic4-2 LOC105027233 LOC105027233 mapk8ip1 mapk8ip1 ENSELUP00000032950 ENSELUP00000032950 map2k7 map2k7 LOC105023895 LOC105023895 Mapk1 Mapk1 ssh1 ssh1 LOC105023083 LOC105023083 fosb fosb LOC105016004 LOC105016004 fosl2 fosl2 LOC105013553 LOC105013553 zfp36l2 zfp36l2 hspb7 hspb7 hsf4 hsf4 LOC105028011 LOC105028011 LOC105029132 LOC105029132 map3k1 map3k1 Ssh2 Ssh2 ptpn5 ptpn5 dusp8 dusp8 LOC105011557 LOC105011557 MAP2K4 MAP2K4 ENSELUP00000038810 ENSELUP00000038810 LOC105014902 LOC105014902 LOC105014911 LOC105014911 LOC105023011 LOC105023011 LOC105028432 LOC105028432 atf2 atf2 LOC105012809 LOC105012809 LOC105012171 LOC105012171
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dusp4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (374 aa)
LOC105029346Cofilin 1; Belongs to the actin-binding proteins ADF family. (217 aa)
LOC105029391FOS-like antigen 1a. (355 aa)
LOC105020225Mitogen-activated protein kinase. (364 aa)
LOC105020226Mitogen-activated protein kinase. (361 aa)
LOC105005941V-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (375 aa)
LOC105014063Si:dkey-1k23.3; Belongs to the small heat shock protein (HSP20) family. (439 aa)
LOC105013860Mitogen-activated protein kinase. (364 aa)
LOC105029097Si:ch211-195b15.8. (541 aa)
LOC105023646Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (489 aa)
ENSELUP00000004609Slingshot protein phosphatase 2b. (804 aa)
LOC105017320MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (409 aa)
ENSELUP00000005325TYR_PHOSPHATASE_2 domain-containing protein. (148 aa)
LOC105006773Uncharacterized protein. (790 aa)
mapk15Mitogen-activated protein kinase. (666 aa)
LOC105011734Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (290 aa)
creb5cAMP responsive element binding protein 5b. (519 aa)
dusp3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (215 aa)
zfp36l1Zinc finger protein 36, C3H type-like 1b. (369 aa)
mapk8ip3Mitogen-activated protein kinase 8 interacting protein 3. (1320 aa)
dusp16Dual specificity phosphatase 16. (764 aa)
LOC105014839Zgc:113162. (332 aa)
ptpn7Uncharacterized protein. (461 aa)
LOC105027407Mitogen-activated protein kinase kinase 6. (290 aa)
ENSELUP00000010466JunB proto-oncogene, AP-1 transcription factor subunit b. (303 aa)
LOC105018531SNF related kinase b. (754 aa)
dusp6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
metrnlMeteorin like, glial cell differentiation regulator a. (292 aa)
ptprrProtein tyrosine phosphatase receptor type R. (773 aa)
LOC105023872Mitogen-activated protein kinase. (359 aa)
JUNDBZIP domain-containing protein. (312 aa)
LOC105023081Zgc:114130. (386 aa)
limk2LIM domain kinase 2. (672 aa)
dusp10Dual specificity phosphatase 10. (493 aa)
ENSELUP00000013778SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (165 aa)
LOC105013205MAPK activated protein kinase 2b. (605 aa)
LOC105020506JunE proto-oncogene, AP-1 transcription factor subunit. (356 aa)
hsbp1Uncharacterized protein. (133 aa)
LOC105028071ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (167 aa)
MEF2DMyocyte enhancer factor 2D. (592 aa)
MAPK9Mitogen-activated protein kinase. (418 aa)
HSBP1Heat shock factor-binding protein 1. (78 aa)
mef2cMyocyte enhancer factor 2cb. (478 aa)
ENSELUP00000017121Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
mob2MOB kinase activator 2a. (263 aa)
mapk4Mitogen-activated protein kinase 4. (720 aa)
LOC105017017Activating transcription factor 7b. (524 aa)
LOC105007426Mitogen-activated protein kinase. (364 aa)
mapkapk5MAPK activated protein kinase 5. (471 aa)
ENSELUP00000020561DDE_3 domain-containing protein. (66 aa)
hsf5Heat shock transcription factor 5. (531 aa)
mapk6Mitogen-activated protein kinase 6. (803 aa)
ENSELUP00000020820Mitogen-activated protein kinase. (345 aa)
hspb1Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (220 aa)
clic2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (245 aa)
Mapk10Mitogen-activated protein kinase. (259 aa)
ENSELUP00000021764JunD proto-oncogene, AP-1 transcription factor subunit. (303 aa)
LOC105026854Zinc finger protein 36, C3H type-like 1a. (395 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (588 aa)
mapk8ip2Mitogen-activated protein kinase 8 interacting protein 2. (1297 aa)
dusp5Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (401 aa)
Hspb3Heat shock protein, alpha-crystallin-related, b3; Belongs to the small heat shock protein (HSP20) family. (144 aa)
atf3Activating transcription factor 3. (200 aa)
LOC105024911Mitogen-activated protein kinase. (421 aa)
ENSELUP00000025951Uncharacterized protein. (238 aa)
LOC114840870SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (211 aa)
hspb2Heat shock protein, alpha-crystallin-related, b2; Belongs to the small heat shock protein (HSP20) family. (165 aa)
JunBZIP domain-containing protein. (314 aa)
LOC105022309Nuclear receptor subfamily 4, group A, member 1. (571 aa)
cfl2Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1123 aa)
ENSELUP00000028193Si:ch211-203d1.3. (523 aa)
batfBasic leucine zipper transcription factor, ATF-like. (136 aa)
LOC105005940Si:ch211-153j24.3. (439 aa)
jkampJnk1/mapk8 associated membrane protein. (307 aa)
LOC105015210Myocyte enhancer factor 2ca. (482 aa)
LOC105006595Mitogen-activated protein kinase. (384 aa)
jdp2Jun dimerization protein 2a. (198 aa)
ENSELUP00000030208V-fos FBJ murine osteosarcoma viral oncogene homolog Aa. (206 aa)
limk1LIM domain kinase 1a. (664 aa)
LOC105007365Protein-serine/threonine kinase. (409 aa)
LOC105020581Mitogen-activated protein kinase kinase 2b; Belongs to the protein kinase superfamily. (399 aa)
clic4-2Chloride intracellular channel protein 4. (239 aa)
LOC105027233Mitogen-activated protein kinase. (469 aa)
mapk8ip1Mitogen-activated protein kinase 8 interacting protein 1a. (801 aa)
ENSELUP00000032950Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (456 aa)
map2k7Mitogen-activated protein kinase kinase 7. (439 aa)
LOC105023895Mitogen-activated protein kinase. (361 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (371 aa)
ssh1Slingshot protein phosphatase 1a. (1028 aa)
LOC105023083Zgc:162730. (358 aa)
fosbFBJ murine osteosarcoma viral oncogene homolog B. (454 aa)
LOC105016004SHSP domain-containing protein. (171 aa)
fosl2Fos-like antigen 2. (343 aa)
LOC105013553Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
zfp36l2Zinc finger protein 36, C3H type-like 2. (425 aa)
hspb7Heat shock protein family, member 7 (cardiovascular); Belongs to the small heat shock protein (HSP20) family. (159 aa)
hsf4Heat shock transcription factor 4. (432 aa)
LOC105028011Cofilin 1 (non-muscle), like; Belongs to the actin-binding proteins ADF family. (164 aa)
LOC105029132Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (376 aa)
map3k1Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase. (1416 aa)
Ssh2Uncharacterized protein. (113 aa)
ptpn5Protein tyrosine phosphatase non-receptor type 5. (576 aa)
dusp8Dual specificity phosphatase 8a. (757 aa)
LOC105011557Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (401 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (434 aa)
ENSELUP00000038810Uncharacterized protein. (50 aa)
LOC105014902Slingshot protein phosphatase 1b. (1044 aa)
LOC105014911Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (206 aa)
LOC105023011Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (426 aa)
LOC105028432Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (186 aa)
atf2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa)
LOC105012809Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
LOC105012171JunB proto-oncogene, AP-1 transcription factor subunit a. (333 aa)
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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