(95 nodes) Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) network (Esox lucius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rpl28	Ribosomal protein L28. (137 aa)
	LOC105013976	60S ribosomal protein L32. (135 aa)
	RPL35	Ribosomal protein L35. (138 aa)
	RPL37	Ribosomal protein L37; Binds to the 23S rRNA. (97 aa)
	rps16	40S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (146 aa)
	rpl4	Ribosomal protein L4. (382 aa)
	RPL5	Ribosomal protein L5. (301 aa)
	rps13	Ribosomal_S13_N domain-containing protein; Belongs to the universal ribosomal protein uS15 family. (151 aa)
	RPS17	Ribosomal protein S17. (134 aa)
	rpl27a	Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family. (148 aa)
	LOC105024418	60S ribosomal protein L26. (145 aa)
	rps12	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
	med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1293 aa)
	rpl35a	Ribosomal protein L35a. (131 aa)
	rpl7	60S ribosomal protein L7. (245 aa)
	rps2	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (263 aa)
	LOC105028025	40S ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (205 aa)
	RPL3L	Ribosomal protein L3 like; Belongs to the universal ribosomal protein uL3 family. (412 aa)
	Rps26	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (123 aa)
	rpl31	Ribosomal protein L31. (125 aa)
	rpl15	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa)
	RPSA	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family. (322 aa)
	rpl34	Ribosomal protein L34. (117 aa)
	rps8	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
	LOC105025040	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL42 family. (143 aa)
	LOC105017549	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. (133 aa)
	arl6ip1	ADP-ribosylation factor-like 6 interacting protein 1. (203 aa)
	rps4x	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (264 aa)
	rpl13	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (211 aa)
	rps9	40S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
	rpl29	60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family. (93 aa)
	Rsrc1	Arginine/serine-rich coiled-coil 1. (202 aa)
	LOC105025806	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL42 family. (128 aa)
	cd74	H-2 class II histocompatibility antigen gamma chain. (281 aa)
	ENSELUP00000016782	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa)
	LOC105011047	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (245 aa)
	rps25	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (143 aa)
	rpl23a	Ribosomal protein L23a. (196 aa)
	rps6	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (252 aa)
	LOC105005646	Ribosomal protein L32. (135 aa)
	LOC105008943	Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family. (479 aa)
	rps18	Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family. (153 aa)
	LOC105024009	Ribosomal protein L5. (298 aa)
	rpl27	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family. (136 aa)
	rpl12	Ribosomal protein L12; Belongs to the universal ribosomal protein uL11 family. (165 aa)
	rps11	Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. (158 aa)
	rps28	Ribosomal protein S28. (75 aa)
	rpl39	Ribosomal protein L39. (102 aa)
	rpl35	Uncharacterized protein. (153 aa)
	rpl10	Ribosomal_L16 domain-containing protein. (215 aa)
	rps19	Ribosomal protein S19. (152 aa)
	rps20	Ribosomal_S10 domain-containing protein. (119 aa)
	LOC105013751	Uncharacterized protein. (134 aa)
	rpl7a	Ribosomal protein L7a. (266 aa)
	rpl11	Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (177 aa)
	rps24	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (132 aa)
	LOC105010844	Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (246 aa)
	rpl17	Uncharacterized protein; Belongs to the universal ribosomal protein uL22 family. (186 aa)
	rpl14	Ribosomal protein L14. (154 aa)
	LOC105013954	40S ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
	rpl7l1	Ribosomal protein L7-like 1. (249 aa)
	rps14	Uncharacterized protein. (161 aa)
	LOC105008443	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (209 aa)
	rpl9	60S ribosomal protein L9. (192 aa)
	rs5	Ribosomal_S7 domain-containing protein; Belongs to the universal ribosomal protein uS7 family. (205 aa)
	rps13-2	40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (151 aa)
	rpl6	Ribosomal protein L6. (259 aa)
	rpl18a	60S ribosomal protein L18a; Belongs to the eukaryotic ribosomal protein eL20 family. (176 aa)
	ENSELUP00000032295	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (225 aa)
	rpl36	60S ribosomal protein L36; Belongs to the eukaryotic ribosomal protein eL36 family. (156 aa)
	RPS29	Ribosomal protein S29. (82 aa)
	rsad1	Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (476 aa)
	rpl37a	Ribosomal protein L37a. (68 aa)
	LOC105022559	Uncharacterized protein. (206 aa)
	rps3a	40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. (344 aa)
	rpl21	Ribosomal protein L21. (160 aa)
	rpl18	Ribosomal protein L18. (188 aa)
	LOC105014690	NAD(P)-bd_dom domain-containing protein. (221 aa)
	rpl13a	Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family. (205 aa)
	rpl30	Ribosomal protein L30. (132 aa)
	rack1	WD_REPEATS_REGION domain-containing protein. (317 aa)
	fau	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. (132 aa)
	RPL19	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (197 aa)
	rps21	Ribosomal protein S21. (183 aa)
	LOC105012928	Interferon-induced protein 35. (403 aa)
	LOC105017455	Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (152 aa)
	rps15	Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (145 aa)
	rps10	S10_plectin domain-containing protein. (172 aa)
	rpl24	Ribosomal protein L24. (151 aa)
	RPLP2	60S acidic ribosomal protein P2; Belongs to the eukaryotic ribosomal protein P1/P2 family. (113 aa)
	rplp1	Ribosomal protein, large, P1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (112 aa)
	LOC105008159	Ribosomal protein, large P2; Belongs to the eukaryotic ribosomal protein P1/P2 family. (146 aa)
	rpl8	Ribosomal protein L8. (286 aa)
	rplp0	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (315 aa)
	LOC105006097	Ribosomal protein L37; Binds to the 23S rRNA. (97 aa)

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSELUP00000016782	ENSELUP00000032295	ENSELUP00000016782	ENSELUP00000032295	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	0.999
ENSELUP00000016782	LOC105005646	ENSELUP00000016782	ENSELUP00000019156	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Ribosomal protein L32.	0.996
ENSELUP00000016782	LOC105006097	ENSELUP00000016782	ENSELUP00000043020	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Ribosomal protein L37; Binds to the 23S rRNA.	0.993
ENSELUP00000016782	LOC105008159	ENSELUP00000016782	ENSELUP00000042318	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Ribosomal protein, large P2; Belongs to the eukaryotic ribosomal protein P1/P2 family.	0.995
ENSELUP00000016782	LOC105008443	ENSELUP00000016782	ENSELUP00000029380	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.994
ENSELUP00000016782	LOC105008943	ENSELUP00000016782	ENSELUP00000019494	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.	0.995
ENSELUP00000016782	LOC105010844	ENSELUP00000016782	ENSELUP00000025691	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.	0.989
ENSELUP00000016782	LOC105011047	ENSELUP00000016782	ENSELUP00000017951	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	0.989
ENSELUP00000016782	LOC105012928	ENSELUP00000016782	ENSELUP00000039076	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Interferon-induced protein 35.	0.996
ENSELUP00000016782	LOC105013751	ENSELUP00000016782	ENSELUP00000022962	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Uncharacterized protein.	0.985
ENSELUP00000016782	LOC105013954	ENSELUP00000016782	ENSELUP00000026123	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	40S ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family.	0.985
ENSELUP00000016782	LOC105013976	ENSELUP00000016782	ENSELUP00000000247	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	60S ribosomal protein L32.	0.996
ENSELUP00000016782	LOC105014690	ENSELUP00000016782	ENSELUP00000035545	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	NAD(P)-bd_dom domain-containing protein.	0.953
ENSELUP00000016782	LOC105017455	ENSELUP00000016782	ENSELUP00000039894	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family.	0.985
ENSELUP00000016782	LOC105017549	ENSELUP00000016782	ENSELUP00000011507	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.999
ENSELUP00000016782	LOC105022559	ENSELUP00000016782	ENSELUP00000035038	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Uncharacterized protein.	0.996
ENSELUP00000016782	LOC105024009	ENSELUP00000016782	ENSELUP00000019776	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Ribosomal protein L5.	0.996
ENSELUP00000016782	LOC105024418	ENSELUP00000016782	ENSELUP00000004191	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	60S ribosomal protein L26.	0.999
ENSELUP00000016782	LOC105025040	ENSELUP00000016782	ENSELUP00000011197	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL42 family.	0.995
ENSELUP00000016782	LOC105025806	ENSELUP00000016782	ENSELUP00000016297	Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL42 family.	0.995