STRINGSTRING
cdca7 cdca7 Ticrr Ticrr rad17 rad17 topbp1 topbp1 cdc6 cdc6 hus1 hus1 DNA2 DNA2 cdt1 cdt1 Tipin Tipin orc1 orc1 CLSPN CLSPN rad9a rad9a ENSELUP00000037811 ENSELUP00000037811 timeless timeless rad9b rad9b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdca7Cell division cycle associated 7a. (419 aa)
TicrrTreslin_N domain-containing protein. (1814 aa)
rad17RAD17 checkpoint clamp loader component. (699 aa)
topbp1DNA topoisomerase II binding protein 1. (1493 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (568 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (283 aa)
DNA2DNA replication helicase/nuclease 2. (1421 aa)
cdt1Chromatin licensing and DNA replication factor 1. (691 aa)
TipinTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (327 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (940 aa)
CLSPNClaspin. (1126 aa)
rad9aRAD9 checkpoint clamp component A. (352 aa)
ENSELUP00000037811BRCT domain-containing protein. (139 aa)
timelessTimeless circadian clock. (1235 aa)
rad9bRAD9 checkpoint clamp component B. (383 aa)
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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