(35 nodes) Transcription corepressor binding network (Esox lucius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lef1	Lymphoid enhancer-binding factor 1. (374 aa)
	LOC105014136	Euchromatic histone-lysine N-methyltransferase 1a. (858 aa)
	ENSELUP00000001779	Zinc finger protein 644b. (1218 aa)
	ENSELUP00000001793	Uncharacterized protein. (232 aa)
	LOC105026762	SIX homeobox 7. (266 aa)
	LOC105018606	CCR4-NOT transcription complex, subunit 2. (560 aa)
	stk36	Serine/threonine kinase 36 (fused homolog, Drosophila). (1143 aa)
	WIZ	WIZ zinc finger. (817 aa)
	six6	SIX homeobox 6a. (245 aa)
	CNOT2	CCR4-NOT transcription complex subunit 2. (533 aa)
	LOC105010770	PHD finger protein 12a. (974 aa)
	six3	SIX homeobox 3a. (342 aa)
	ctbp1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (435 aa)
	PER2	Period circadian regulator 2. (1109 aa)
	HDGF	Heparin binding growth factor. (225 aa)
	LOC105024595	Period circadian clock 1a. (1406 aa)
	nr1d1	Nuclear receptor subfamily 1, group d, member 1. (610 aa)
	CTBP2	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (432 aa)
	ENSELUP00000015405	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (398 aa)
	LOC105012670	THAP domain containing 7. (645 aa)
	LOC105010817	PHD finger protein 12b. (1043 aa)
	fam89a	Family with sequence similarity 89 member A. (170 aa)
	LOC105012169	Si:dkey-217d24.6. (806 aa)
	eed	Embryonic ectoderm development. (442 aa)
	ehmt2	Euchromatic histone-lysine N-methyltransferase 2. (1201 aa)
	LOC105010572	C-terminal binding protein 2a; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (457 aa)
	LOC105018507	Period circadian clock 2. (1580 aa)
	LOC105013636	Nuclear receptor subfamily 1, group D, member 4a. (581 aa)
	ehmt1	Euchromatic histone-lysine N-methyltransferase 1b. (1320 aa)
	LOC105020739	Period circadian clock 1b. (1396 aa)
	LOC105023942	Zinc finger protein 644a. (1182 aa)
	LOC105012960	Elongin B. (119 aa)
	LOC105011287	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (421 aa)
	LOC105030139	Ubiquitin-like domain-containing protein. (122 aa)
	LOC106024346	Family with sequence similarity 89 member B. (176 aa)

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNOT2	LOC105018606	ENSELUP00000011694	ENSELUP00000006390	CCR4-NOT transcription complex subunit 2.	CCR4-NOT transcription complex, subunit 2.	0.900
CTBP2	lef1	ENSELUP00000015130	ENSELUP00000016952	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Lymphoid enhancer-binding factor 1.	0.494
ENSELUP00000001779	ENSELUP00000001793	ENSELUP00000001779	ENSELUP00000001793	Zinc finger protein 644b.	Uncharacterized protein.	0.819
ENSELUP00000001793	ENSELUP00000001779	ENSELUP00000001793	ENSELUP00000001779	Uncharacterized protein.	Zinc finger protein 644b.	0.819
ENSELUP00000015405	lef1	ENSELUP00000015405	ENSELUP00000016952	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Lymphoid enhancer-binding factor 1.	0.494
LOC105010572	ctbp1	ENSELUP00000029522	ENSELUP00000012808	C-terminal binding protein 2a; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.901
LOC105010572	lef1	ENSELUP00000029522	ENSELUP00000016952	C-terminal binding protein 2a; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Lymphoid enhancer-binding factor 1.	0.494
LOC105011287	lef1	ENSELUP00000041029	ENSELUP00000016952	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Lymphoid enhancer-binding factor 1.	0.494
LOC105012169	LOC105014136	ENSELUP00000025690	ENSELUP00000000522	Si:dkey-217d24.6.	Euchromatic histone-lysine N-methyltransferase 1a.	0.521
LOC105012169	ehmt1	ENSELUP00000025690	ENSELUP00000031281	Si:dkey-217d24.6.	Euchromatic histone-lysine N-methyltransferase 1b.	0.521
LOC105012169	ehmt2	ENSELUP00000025690	ENSELUP00000028994	Si:dkey-217d24.6.	Euchromatic histone-lysine N-methyltransferase 2.	0.521
LOC105012960	LOC105030139	ENSELUP00000039736	ENSELUP00000042214	Elongin B.	Ubiquitin-like domain-containing protein.	0.901
LOC105014136	LOC105012169	ENSELUP00000000522	ENSELUP00000025690	Euchromatic histone-lysine N-methyltransferase 1a.	Si:dkey-217d24.6.	0.521
LOC105014136	WIZ	ENSELUP00000000522	ENSELUP00000009797	Euchromatic histone-lysine N-methyltransferase 1a.	WIZ zinc finger.	0.521
LOC105014136	eed	ENSELUP00000000522	ENSELUP00000026134	Euchromatic histone-lysine N-methyltransferase 1a.	Embryonic ectoderm development.	0.560
LOC105018507	nr1d1	ENSELUP00000029545	ENSELUP00000015018	Period circadian clock 2.	Nuclear receptor subfamily 1, group d, member 1.	0.483
LOC105018606	CNOT2	ENSELUP00000006390	ENSELUP00000011694	CCR4-NOT transcription complex, subunit 2.	CCR4-NOT transcription complex subunit 2.	0.900
LOC105020739	nr1d1	ENSELUP00000032560	ENSELUP00000015018	Period circadian clock 1b.	Nuclear receptor subfamily 1, group d, member 1.	0.544
LOC105024595	nr1d1	ENSELUP00000014381	ENSELUP00000015018	Period circadian clock 1a.	Nuclear receptor subfamily 1, group d, member 1.	0.598
LOC105030139	LOC105012960	ENSELUP00000042214	ENSELUP00000039736	Ubiquitin-like domain-containing protein.	Elongin B.	0.901