12 items (Esox lucius) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	pan2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1208 aa)
	ENSELUP00000033211	Nocturnin. (430 aa)
	toe1	Target of EGR1, exonuclease. (527 aa)
	parn	Poly(A)-specific ribonuclease (deadenylation nuclease). (754 aa)
	LRRC27	Leucine rich repeat containing 27. (474 aa)
	LOC105025822	Endo/exonuclease/phosphatase domain-containing protein. (568 aa)
	cnot6l	CCR4-NOT transcription complex, subunit 6-like. (629 aa)
	LOC105024905	CCR4-NOT transcription complex, subunit 6a. (557 aa)
	cnot8	CCR4-NOT transcription complex, subunit 8. (285 aa)
	LOC105026542	CCR4-NOT transcription complex, subunit 7. (286 aa)
	LOC105029048	Nocturnin. (461 aa)
	pde12	Phosphodiesterase 12. (597 aa)

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSELUP00000033211	LOC105026542	ENSELUP00000033211	ENSELUP00000009302	Nocturnin.	CCR4-NOT transcription complex, subunit 7.	0.780
ENSELUP00000033211	cnot8	ENSELUP00000033211	ENSELUP00000010397	Nocturnin.	CCR4-NOT transcription complex, subunit 8.	0.780
ENSELUP00000033211	pan2	ENSELUP00000033211	ENSELUP00000025731	Nocturnin.	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...]	0.515
ENSELUP00000033211	parn	ENSELUP00000033211	ENSELUP00000034535	Nocturnin.	Poly(A)-specific ribonuclease (deadenylation nuclease).	0.481
LOC105024905	LOC105025822	ENSELUP00000043086	ENSELUP00000016123	CCR4-NOT transcription complex, subunit 6a.	Endo/exonuclease/phosphatase domain-containing protein.	0.900
LOC105024905	LOC105026542	ENSELUP00000043086	ENSELUP00000009302	CCR4-NOT transcription complex, subunit 6a.	CCR4-NOT transcription complex, subunit 7.	0.861
LOC105024905	cnot6l	ENSELUP00000043086	ENSELUP00000013199	CCR4-NOT transcription complex, subunit 6a.	CCR4-NOT transcription complex, subunit 6-like.	0.906
LOC105024905	cnot8	ENSELUP00000043086	ENSELUP00000010397	CCR4-NOT transcription complex, subunit 6a.	CCR4-NOT transcription complex, subunit 8.	0.847
LOC105024905	pan2	ENSELUP00000043086	ENSELUP00000025731	CCR4-NOT transcription complex, subunit 6a.	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...]	0.556
LOC105025822	LOC105024905	ENSELUP00000016123	ENSELUP00000043086	Endo/exonuclease/phosphatase domain-containing protein.	CCR4-NOT transcription complex, subunit 6a.	0.900
LOC105025822	LOC105026542	ENSELUP00000016123	ENSELUP00000009302	Endo/exonuclease/phosphatase domain-containing protein.	CCR4-NOT transcription complex, subunit 7.	0.861
LOC105025822	cnot6l	ENSELUP00000016123	ENSELUP00000013199	Endo/exonuclease/phosphatase domain-containing protein.	CCR4-NOT transcription complex, subunit 6-like.	0.906
LOC105025822	cnot8	ENSELUP00000016123	ENSELUP00000010397	Endo/exonuclease/phosphatase domain-containing protein.	CCR4-NOT transcription complex, subunit 8.	0.847
LOC105025822	pan2	ENSELUP00000016123	ENSELUP00000025731	Endo/exonuclease/phosphatase domain-containing protein.	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...]	0.556
LOC105026542	ENSELUP00000033211	ENSELUP00000009302	ENSELUP00000033211	CCR4-NOT transcription complex, subunit 7.	Nocturnin.	0.780
LOC105026542	LOC105024905	ENSELUP00000009302	ENSELUP00000043086	CCR4-NOT transcription complex, subunit 7.	CCR4-NOT transcription complex, subunit 6a.	0.861
LOC105026542	LOC105025822	ENSELUP00000009302	ENSELUP00000016123	CCR4-NOT transcription complex, subunit 7.	Endo/exonuclease/phosphatase domain-containing protein.	0.861
LOC105026542	LOC105029048	ENSELUP00000009302	ENSELUP00000000996	CCR4-NOT transcription complex, subunit 7.	Nocturnin.	0.780
LOC105026542	LRRC27	ENSELUP00000009302	ENSELUP00000038671	CCR4-NOT transcription complex, subunit 7.	Leucine rich repeat containing 27.	0.833
LOC105026542	cnot6l	ENSELUP00000009302	ENSELUP00000013199	CCR4-NOT transcription complex, subunit 7.	CCR4-NOT transcription complex, subunit 6-like.	0.902