(38 nodes) Maturation of SSU-rRNA network (Esox lucius)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	ENSELUP00000005104	Ddb1 and cul4 associated factor 13. (414 aa)
	nat10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1033 aa)
	utp23	UTP23 small subunit processome component. (249 aa)
	nop9	Uncharacterized protein. (688 aa)
	LOC105019722	PWP2 small subunit processome component. (919 aa)
	bms1	BMS1 ribosome biogenesis factor. (1226 aa)
	utp4	UTP4 small subunit processome component. (684 aa)
	tsr3	Probable ribosome biogenesis protein; Probable pre-rRNA processing protein involved in ribosome biogenesis. (302 aa)
	dhx37	DEAH (Asp-Glu-Ala-His) box polypeptide 37. (1149 aa)
	nop14	NOP14 nucleolar protein homolog (yeast). (873 aa)
	wdr46	WD repeat domain 46. (592 aa)
	tsr1	TSR1 ribosome maturation factor. (867 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	fam207a	Family with sequence similarity 207 member A. (254 aa)
	Rrs1	Ribosome biogenesis regulator 1 homolog. (150 aa)
	tsr2	Uncharacterized protein. (186 aa)
	wdr3	WD repeat domain 3. (941 aa)
	heatr1	HEAT repeat containing 1. (2147 aa)
	utp3	UTP3 small subunit processome component. (521 aa)
	ngdn	Neuroguidin, EIF4E binding protein. (345 aa)
	wdr43	WD repeat domain 43. (675 aa)
	ENSELUP00000018978	BUD22 domain-containing protein. (438 aa)
	Ddx52	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52. (565 aa)
	riok3	Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (507 aa)
	riok1	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (547 aa)
	rpp40	Ribonuclease P/MRP 40 subunit. (361 aa)
	mrps11	28S ribosomal protein S11, mitochondrial; Belongs to the universal ribosomal protein uS11 family. (198 aa)
	nol10	Nucleolar protein 10. (721 aa)
	utp25	UTP25 small subunit processor component. (757 aa)
	nol11	Nucleolar protein 11. (723 aa)
	lsm6	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (88 aa)
	bysl	Bystin-like. (450 aa)
	helb	Helicase (DNA) B. (1242 aa)
	ENSELUP00000010740	RIO kinase 2 (yeast). (418 aa)
	kri1	KRI1 homolog. (755 aa)
	abt1	Uncharacterized protein. (280 aa)
	ENSELUP00000006512	Transducin (beta)-like 3. (630 aa)
	utp6	UTP6 small subunit processome component. (594 aa)

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ddx52	ENSELUP00000005104	ENSELUP00000018526	ENSELUP00000005104	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	Ddb1 and cul4 associated factor 13.	0.986
Ddx52	ENSELUP00000006512	ENSELUP00000018526	ENSELUP00000006512	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	Transducin (beta)-like 3.	0.746
Ddx52	ENSELUP00000010740	ENSELUP00000018526	ENSELUP00000010740	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	RIO kinase 2 (yeast).	0.649
Ddx52	LOC105019722	ENSELUP00000018526	ENSELUP00000000272	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	PWP2 small subunit processome component.	0.885
Ddx52	Rrs1	ENSELUP00000018526	ENSELUP00000035906	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	Ribosome biogenesis regulator 1 homolog.	0.706
Ddx52	abt1	ENSELUP00000018526	ENSELUP00000007155	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	Uncharacterized protein.	0.832
Ddx52	bms1	ENSELUP00000018526	ENSELUP00000000146	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	BMS1 ribosome biogenesis factor.	0.894
Ddx52	bysl	ENSELUP00000018526	ENSELUP00000014162	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	Bystin-like.	0.949
Ddx52	dhx37	ENSELUP00000018526	ENSELUP00000031436	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	DEAH (Asp-Glu-Ala-His) box polypeptide 37.	0.790
Ddx52	heatr1	ENSELUP00000018526	ENSELUP00000028646	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	HEAT repeat containing 1.	0.905
Ddx52	kri1	ENSELUP00000018526	ENSELUP00000009576	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	KRI1 homolog.	0.761
Ddx52	mrps11	ENSELUP00000018526	ENSELUP00000016648	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	28S ribosomal protein S11, mitochondrial; Belongs to the universal ribosomal protein uS11 family.	0.630
Ddx52	nat10	ENSELUP00000018526	ENSELUP00000004833	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.889
Ddx52	ngdn	ENSELUP00000018526	ENSELUP00000023840	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	Neuroguidin, EIF4E binding protein.	0.947
Ddx52	nol10	ENSELUP00000018526	ENSELUP00000014658	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	Nucleolar protein 10.	0.894
Ddx52	nol11	ENSELUP00000018526	ENSELUP00000014508	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	Nucleolar protein 11.	0.704
Ddx52	nop14	ENSELUP00000018526	ENSELUP00000030760	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	NOP14 nucleolar protein homolog (yeast).	0.991
Ddx52	nop9	ENSELUP00000018526	ENSELUP00000003829	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	Uncharacterized protein.	0.843
Ddx52	riok1	ENSELUP00000018526	ENSELUP00000017314	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.	0.615
Ddx52	riok3	ENSELUP00000018526	ENSELUP00000018097	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52.	Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.	0.449