13 items (Esox lucius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rad9b	RAD9 checkpoint clamp component B. (383 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (962 aa)
	chek2	Checkpoint kinase 2. (513 aa)
	mre11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (702 aa)
	xpc	Xeroderma pigmentosum, complementation group C. (931 aa)
	hus1	Checkpoint protein; Belongs to the HUS1 family. (283 aa)
	fancd2	FA complementation group D2. (1408 aa)
	Tipin	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (327 aa)
	cdca7	Cell division cycle associated 7a. (419 aa)
	rad9a	RAD9 checkpoint clamp component A. (352 aa)
	Eme2	ERCC4 domain-containing protein. (331 aa)
	mus81	MUS81 structure-specific endonuclease subunit. (617 aa)
	eme1	Essential meiotic structure-specific endonuclease 1. (590 aa)

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Eme2	eme1	ENSELUP00000031129	ENSELUP00000042082	ERCC4 domain-containing protein.	Essential meiotic structure-specific endonuclease 1.	0.688
Eme2	fancd2	ENSELUP00000031129	ENSELUP00000018341	ERCC4 domain-containing protein.	FA complementation group D2.	0.425
Eme2	mre11	ENSELUP00000031129	ENSELUP00000010046	ERCC4 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.489
Eme2	mus81	ENSELUP00000031129	ENSELUP00000031652	ERCC4 domain-containing protein.	MUS81 structure-specific endonuclease subunit.	0.985
Tipin	cdca7	ENSELUP00000020179	ENSELUP00000023624	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	Cell division cycle associated 7a.	0.612
Tipin	chek2	ENSELUP00000020179	ENSELUP00000002038	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	Checkpoint kinase 2.	0.747
Tipin	hus1	ENSELUP00000020179	ENSELUP00000016476	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	Checkpoint protein; Belongs to the HUS1 family.	0.835
Tipin	mus81	ENSELUP00000020179	ENSELUP00000031652	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	MUS81 structure-specific endonuclease subunit.	0.515
Tipin	rad9a	ENSELUP00000020179	ENSELUP00000025909	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	RAD9 checkpoint clamp component A.	0.704
Tipin	rad9b	ENSELUP00000020179	ENSELUP00000043031	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	RAD9 checkpoint clamp component B.	0.704
cdca7	Tipin	ENSELUP00000023624	ENSELUP00000020179	Cell division cycle associated 7a.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.612
cdca7	chek2	ENSELUP00000023624	ENSELUP00000002038	Cell division cycle associated 7a.	Checkpoint kinase 2.	0.634
cdca7	hus1	ENSELUP00000023624	ENSELUP00000016476	Cell division cycle associated 7a.	Checkpoint protein; Belongs to the HUS1 family.	0.955
cdca7	mre11	ENSELUP00000023624	ENSELUP00000010046	Cell division cycle associated 7a.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.667
cdca7	mus81	ENSELUP00000023624	ENSELUP00000031652	Cell division cycle associated 7a.	MUS81 structure-specific endonuclease subunit.	0.437
chek2	Tipin	ENSELUP00000002038	ENSELUP00000020179	Checkpoint kinase 2.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.747
chek2	cdca7	ENSELUP00000002038	ENSELUP00000023624	Checkpoint kinase 2.	Cell division cycle associated 7a.	0.634
chek2	fancd2	ENSELUP00000002038	ENSELUP00000018341	Checkpoint kinase 2.	FA complementation group D2.	0.587
chek2	hus1	ENSELUP00000002038	ENSELUP00000016476	Checkpoint kinase 2.	Checkpoint protein; Belongs to the HUS1 family.	0.682
chek2	mre11	ENSELUP00000002038	ENSELUP00000010046	Checkpoint kinase 2.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.842