STRINGSTRING
LOC105030252 LOC105030252 usp7 usp7 hspbp1 hspbp1 LOC105015312 LOC105015312 ENSELUP00000012562 ENSELUP00000012562 anapc2 anapc2 bag5 bag5 smg5 smg5 prkar2a prkar2a cct2 cct2 vcl vcl hm13 hm13 rtn1 rtn1 ywhae ywhae Mc1r Mc1r LOC105014826 LOC105014826 det1 det1 ENSELUP00000009360 ENSELUP00000009360 LOC105025443 LOC105025443 LOC105010680 LOC105010680 LOC105008548 LOC105008548 LOC105020812 LOC105020812 fhit fhit spart spart LOC105031055 LOC105031055 faf1 faf1 ENSELUP00000007200 ENSELUP00000007200 ralb ralb LOC105015142 LOC105015142 LOC105011734 LOC105011734 UBE2K UBE2K brca1 brca1 LOC105013606 LOC105013606 stx8 stx8 ubxn7 ubxn7 nfkbia nfkbia LOC105025097 LOC105025097 LOC105013652 LOC105013652 Fzd5 Fzd5 LOC105019203 LOC105019203 ENSELUP00000004023 ENSELUP00000004023 ENSELUP00000003883 ENSELUP00000003883 ENSELUP00000003468 ENSELUP00000003468 LOC105021468 LOC105021468 traf3 traf3 wbp1l wbp1l LOC105014393 LOC105014393 LOC105024639 LOC105024639 LOC105016494 LOC105016494 dbt dbt Fzd8 Fzd8 chek2 chek2 psma3 psma3 ankra2 ankra2 bag4 bag4 ARRDC1 ARRDC1 ENSELUP00000000084 ENSELUP00000000084 LOC105030139 LOC105030139 LOC105017393 LOC105017393 LOC105008258 LOC105008258 mfhas1 mfhas1 smad6 smad6 prkaca prkaca hltf hltf LOC105014657 LOC105014657 arrdc1 arrdc1 wfs1 wfs1 CUL7 CUL7 LOC105027305 LOC105027305 ube2j1 ube2j1 Slf1 Slf1 LOC105018104 LOC105018104 LOC105009772 LOC105009772 LOC105005922 LOC105005922 ccdc51 ccdc51 LOC105024444 LOC105024444 LOC105014886 LOC105014886 ube2a ube2a axin1 axin1 shprh shprh ripk1 ripk1 tank tank LOC105025082 LOC105025082 LOC105012960 LOC105012960 ube2g1 ube2g1 bag2 bag2 ENSELUP00000040486 ENSELUP00000040486 traf4 traf4 LOC105013090 LOC105013090 LOC105017071 LOC105017071 LOC105024762 LOC105024762 ENSELUP00000021127 ENSELUP00000021127 cul4b cul4b ndufs2 ndufs2 LOC105009392 LOC105009392 asb4 asb4 faf2 faf2 camlg camlg LOC105023960 LOC105023960 LOC105026169 LOC105026169 LOC105031565 LOC105031565 rad18 rad18 CUL5 CUL5 LOC105018981 LOC105018981 RALB RALB pdlim2 pdlim2 TRAF5 TRAF5 LOC105027577 LOC105027577 prkar1a prkar1a PRKAR2B PRKAR2B rffl rffl SPOP SPOP smad7 smad7 fbxo7 fbxo7 LOC105010695 LOC105010695 ENSELUP00000032389 ENSELUP00000032389 rnf40 rnf40 LOC105012797 LOC105012797 CUL1 CUL1 map1lc3b map1lc3b LOC105006190 LOC105006190 fzd4 fzd4 CUL3 CUL3 cacybp cacybp ENSELUP00000033483 ENSELUP00000033483 fancl fancl trim37 trim37 LOC105022719 LOC105022719 LOC105015035 LOC105015035 ENSELUP00000034457 ENSELUP00000034457 ENSELUP00000034469 ENSELUP00000034469 LOC105026211 LOC105026211 ENSELUP00000035073 ENSELUP00000035073 LOC105012721 LOC105012721 hspa9 hspa9 wrap53 wrap53 LOC105006338 LOC105006338 bcl10 bcl10 cul4a cul4a LOC105010781 LOC105010781 LOC105014186 LOC105014186 LOC105008592 LOC105008592 LOC105014760 LOC105014760 FZD5 FZD5 blzf1 blzf1 LOC105018664 LOC105018664 cul2 cul2 LOC105020554 LOC105020554 rtn4 rtn4 pink1 pink1 mul1 mul1 psmd1 psmd1 jkamp jkamp LOC105021259 LOC105021259 LOC105021271 LOC105021271 LOC105025131 LOC105025131 LOC105014365 LOC105014365 LOC105026129 LOC105026129 LOC105010654 LOC105010654 LOC105025708 LOC105025708 ube2a-2 ube2a-2 LOC105029719 LOC105029719 rb1 rb1 ppargc1a ppargc1a LOC105025207 LOC105025207 LOC105006321 LOC105006321 prkn prkn LOC105017205 LOC105017205 LOC105019036 LOC105019036 gabarapl2 gabarapl2 sncaip sncaip LOC105025787 LOC105025787 slc25a20 slc25a20 scamp3 scamp3 LOC105008045 LOC105008045 map1lc3a map1lc3a ube2b ube2b LOC105019307 LOC105019307 LOC105013587 LOC105013587 LOC105016950 LOC105016950 cacul1 cacul1 sqstm1 sqstm1 ENSELUP00000022726 ENSELUP00000022726 ENSELUP00000023002 ENSELUP00000023002 tsg101 tsg101 LOC105027321 LOC105027321 prr5l prr5l rnf34 rnf34 LOC105024034 LOC105024034 derl1 derl1 ube2j2 ube2j2 nlk nlk prkar1b prkar1b LOC105011392 LOC105011392 map1lc3c map1lc3c LOC105019579 LOC105019579 laptm4b laptm4b ENSELUP00000014882 ENSELUP00000014882 pacrg pacrg gabarap gabarap hspa5 hspa5 LOC105020506 LOC105020506 ccdc50 ccdc50 LOC105024245 LOC105024245 LOC105030307 LOC105030307 LOC105023970 LOC105023970 Polr2a Polr2a ENSELUP00000013789 ENSELUP00000013789 AXIN2 AXIN2 trib2 trib2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105030252Uncharacterized protein. (881 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1108 aa)
hspbp1HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1. (335 aa)
LOC105015312Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (314 aa)
ENSELUP00000012562Leucine-rich pentatricopeptide repeat containing. (1270 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (808 aa)
bag5BCL2 associated athanogene 5. (479 aa)
smg5SMG5 nonsense mediated mRNA decay factor. (1114 aa)
prkar2aProtein kinase, cAMP-dependent, regulatory, type II, alpha A. (395 aa)
cct2Chaperonin containing TCP1, subunit 2 (beta). (424 aa)
vclVinculin b. (1067 aa)
hm13Histocompatibility (minor) 13. (426 aa)
rtn1Reticulon. (740 aa)
ywhaeTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1; Belongs to the 14-3-3 family. (255 aa)
Mc1rMelanocyte-stimulating hormone receptor. (328 aa)
LOC105014826Ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (171 aa)
det1DET1 partner of COP1 E3 ubiquitin ligase. (551 aa)
ENSELUP00000009360Speckle type BTB/POZ protein like b. (324 aa)
LOC105025443TNFR-Cys domain-containing protein. (278 aa)
LOC105010680Vinculin a. (1134 aa)
LOC105008548V-ral simian leukemia viral oncogene homolog Aa (ras related). (206 aa)
LOC105020812Wolfram syndrome 1a (wolframin). (865 aa)
fhitBis(5'-adenosyl)-triphosphatase. (154 aa)
spartSpartin a. (571 aa)
LOC105031055Arrestin_C domain-containing protein. (396 aa)
faf1Fas (TNFRSF6) associated factor 1. (664 aa)
ENSELUP00000007200Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (589 aa)
ralbUncharacterized protein. (208 aa)
LOC105015142TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (596 aa)
LOC105011734Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (290 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
brca1Uncharacterized protein. (1565 aa)
LOC105013606Uncharacterized protein; Belongs to the BI1 family. (301 aa)
stx8Syntaxin 8. (235 aa)
ubxn7UBX domain protein 7. (541 aa)
nfkbiaANK_REP_REGION domain-containing protein. (322 aa)
LOC105025097Si:dkey-181m9.8. (868 aa)
LOC105013652Tumor necrosis factor receptor superfamily member 5. (322 aa)
Fzd5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (573 aa)
LOC105019203Uncharacterized protein. (226 aa)
ENSELUP00000004023Uncharacterized protein. (826 aa)
ENSELUP00000003883CARD domain-containing protein. (235 aa)
ENSELUP00000003468Ubiquitin-like domain-containing protein. (86 aa)
LOC105021468NEDD8 ubiquitin like modifier, like. (88 aa)
traf3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (576 aa)
wbp1lWW domain binding protein 1-like b. (379 aa)
LOC105014393TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (576 aa)
LOC105024639Reticulon. (215 aa)
LOC105016494Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (499 aa)
Fzd8Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (594 aa)
chek2Checkpoint kinase 2. (513 aa)
psma3Proteasome subunit alpha type. (261 aa)
ankra2Ankyrin repeat, family A (RFXANK-like), 2. (337 aa)
bag4BCL2 associated athanogene 4. (419 aa)
ARRDC1Arrestin domain containing 1. (477 aa)
ENSELUP00000000084TNFR-Cys domain-containing protein. (194 aa)
LOC105030139Ubiquitin-like domain-containing protein. (122 aa)
LOC105017393Uncharacterized protein. (547 aa)
LOC105008258Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (477 aa)
mfhas1Malignant fibrous histiocytoma amplified sequence 1. (1022 aa)
smad6Mothers against decapentaplegic homolog. (490 aa)
prkacaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (351 aa)
hltfHelicase-like transcription factor. (952 aa)
LOC105014657TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa)
arrdc1Arrestin domain containing 1b. (436 aa)
wfs1Wolfram syndrome 1b (wolframin). (964 aa)
CUL7Cullin 7; Belongs to the cullin family. (2582 aa)
LOC105027305BCL2 apoptosis regulator a. (229 aa)
ube2j1Ubiquitin-conjugating enzyme E2, J1. (323 aa)
Slf1ANK_REP_REGION domain-containing protein. (352 aa)
LOC105018104Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
LOC105009772TNFR-Cys domain-containing protein. (316 aa)
LOC10500592214_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
ccdc51Deoxyribonuclease; Belongs to the DNase I family. (266 aa)
LOC105024444Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC105014886Ring finger protein 34b. (409 aa)
ube2aUbiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
axin1Axin 1. (873 aa)
shprhSNF2 histone linker PHD RING helicase. (1626 aa)
ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (723 aa)
tankTRAF family member-associated NFKB activator. (367 aa)
LOC105025082Ran GTPase activating protein 1b. (563 aa)
LOC105012960Elongin B. (119 aa)
ube2g1Ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
bag2BCL2 associated athanogene 2. (209 aa)
ENSELUP00000040486Speckle type BTB/POZ protein. (344 aa)
traf4TNF receptor-associated factor. (477 aa)
LOC105013090Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (379 aa)
LOC105017071Tribbles pseudokinase 3. (356 aa)
LOC105024762Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (564 aa)
ENSELUP00000021127Uncharacterized protein. (294 aa)
cul4bCullin 4B; Belongs to the cullin family. (858 aa)
ndufs2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (506 aa)
LOC105009392Ubiquitin associated and SH3 domain containing Ba. (747 aa)
asb4Ankyrin repeat and SOCS box containing 4. (448 aa)
faf2Fas associated factor family member 2. (445 aa)
camlgCalcium modulating ligand. (299 aa)
LOC105023960Glomulin, FKBP associated protein a. (631 aa)
LOC105026169Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
LOC105031565Sorting nexin. (548 aa)
rad18RAD18 E3 ubiquitin protein ligase. (514 aa)
CUL5Cullin 5; Belongs to the cullin family. (789 aa)
LOC105018981BCL2 apoptosis regulator b. (225 aa)
RALBRAS like proto-oncogene B. (203 aa)
pdlim2PDZ and LIM domain 2 (mystique). (373 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
LOC105027577Zgc:110626. (580 aa)
prkar1aProtein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b. (379 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (406 aa)
rfflRing finger and FYVE-like domain containing E3 ubiquitin protein ligase. (358 aa)
SPOPSpeckle type BTB/POZ protein. (374 aa)
smad7Mothers against decapentaplegic homolog. (377 aa)
fbxo7F-box protein 7. (478 aa)
LOC105010695ER lipid raft associated 1. (330 aa)
ENSELUP00000032389Uncharacterized protein. (476 aa)
rnf40E3 ubiquitin protein ligase. (982 aa)
LOC105012797Uncharacterized protein. (517 aa)
CUL1Cullin 1; Belongs to the cullin family. (783 aa)
map1lc3bMicrotubule-associated protein 1 light chain 3 beta. (125 aa)
LOC105006190Uncharacterized protein; Belongs to the peptidase C14A family. (450 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (534 aa)
CUL3Cullin 3; Belongs to the cullin family. (766 aa)
cacybpCalcyclin-binding protein. (230 aa)
ENSELUP00000033483Uncharacterized protein. (158 aa)
fanclFA complementation group L. (373 aa)
trim37RAB guanine nucleotide exchange factor (GEF) 1. (1466 aa)
LOC105022719Uncharacterized protein. (1081 aa)
LOC105015035TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (533 aa)
ENSELUP00000034457Reticulon. (1109 aa)
ENSELUP00000034469V-ski avian sarcoma viral oncogene homolog a. (713 aa)
LOC105026211Ubiquitin-like domain-containing protein. (128 aa)
ENSELUP00000035073Uncharacterized protein. (246 aa)
LOC105012721Thioredoxin interacting protein a. (395 aa)
hspa9Heat shock protein 9; Belongs to the heat shock protein 70 family. (682 aa)
wrap53WD repeat containing, antisense to TP53. (554 aa)
LOC105006338Nerve growth factor receptor b. (433 aa)
bcl10BCL10 immune signaling adaptor. (267 aa)
cul4aCullin 4A; Belongs to the cullin family. (760 aa)
LOC105010781Spartin b. (628 aa)
LOC105014186UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (169 aa)
LOC105008592Gamma-aminobutyric acid receptor-associated protein. (123 aa)
LOC105014760Ubiquitin-conjugating enzyme E2L 3a; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (567 aa)
blzf1Basic leucine zipper nuclear factor 1. (441 aa)
LOC105018664Autophagy/beclin-1 regulator 1b. (1454 aa)
cul2Cullin 2; Belongs to the cullin family. (776 aa)
LOC105020554Ubiquitin-like domain-containing protein. (88 aa)
rtn4Reticulon. (988 aa)
pink1PTEN induced kinase 1. (580 aa)
mul1Mitochondrial E3 ubiquitin protein ligase 1b. (357 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (938 aa)
jkampJnk1/mapk8 associated membrane protein. (307 aa)
LOC105021259Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (485 aa)
LOC105021271Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (417 aa)
LOC105025131Uncharacterized protein. (206 aa)
LOC105014365Cholesterol 25-hydroxylase like 3. (330 aa)
LOC105026129Axin 2 (conductin, axil). (848 aa)
LOC105010654CULLIN_2 domain-containing protein; Belongs to the cullin family. (780 aa)
LOC105025708Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
ube2a-2Ubiquitin-conjugating enzyme E2A. (143 aa)
LOC105029719Protein kinase cAMP-dependent type II regulatory subunit beta. (405 aa)
rb1Retinoblastoma 1. (909 aa)
ppargc1aPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1259 aa)
LOC105025207E3 ubiquitin protein ligase. (1080 aa)
LOC105006321Tribbles pseudokinase 1. (355 aa)
prknRBR-type E3 ubiquitin transferase. (333 aa)
LOC105017205Proliferation-associated 2G4, a. (393 aa)
LOC105019036Activation-induced cytidine deaminase. (213 aa)
gabarapl2GABA type A receptor associated protein like 2. (117 aa)
sncaipSynuclein, alpha interacting protein. (874 aa)
LOC105025787RAN GTPase activating protein 1a. (581 aa)
slc25a20Protein kinase, cAMP-dependent, regulatory, type II, alpha, B. (414 aa)
scamp3Secretory carrier-associated membrane protein. (348 aa)
LOC105008045Proliferation-associated 2G4, b. (396 aa)
map1lc3aMicrotubule-associated protein 1 light chain 3 alpha. (121 aa)
ube2bUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC105019307Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
LOC105013587Mothers against decapentaplegic homolog. (508 aa)
LOC105016950Testis enhanced gene transcript (BAX inhibitor 1); Belongs to the BI1 family. (239 aa)
cacul1CDK2 associated cullin domain 1; Belongs to the cullin family. (217 aa)
sqstm1Sequestosome 1. (472 aa)
ENSELUP00000022726Uncharacterized protein. (1639 aa)
ENSELUP00000023002Nerve growth factor receptor a (TNFR superfamily, member 16). (405 aa)
tsg101Tumor susceptibility 101a. (390 aa)
LOC105027321Autophagy/beclin-1 regulator 1a. (1413 aa)
prr5lSi:ch211-147k10.5. (341 aa)
rnf34Ring finger protein 34a. (389 aa)
LOC105024034Ubiquitin associated and SH3 domain containing Bb. (645 aa)
derl1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (252 aa)
ube2j2Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast). (261 aa)
nlkMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (530 aa)
prkar1bProtein kinase, cAMP-dependent, regulatory, type I, beta. (380 aa)
LOC105011392Cullin 3; Belongs to the cullin family. (767 aa)
map1lc3cMicrotubule-associated protein 1 light chain 3 gamma. (136 aa)
LOC105019579Uncharacterized protein. (1113 aa)
laptm4bLysosomal protein transmembrane 4 beta. (225 aa)
ENSELUP00000014882CARD domain-containing protein. (196 aa)
pacrgPARK2 co-regulated. (237 aa)
gabarapGamma-aminobutyric acid receptor-associated protein. (122 aa)
hspa5Heat shock protein 5; Belongs to the heat shock protein 70 family. (653 aa)
LOC105020506JunE proto-oncogene, AP-1 transcription factor subunit. (356 aa)
ccdc50Coiled-coil domain containing 50. (620 aa)
LOC105024245Cullin 1a; Belongs to the cullin family. (777 aa)
LOC105030307Sorting nexin. (628 aa)
LOC105023970Zgc:171740. (349 aa)
Polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1892 aa)
ENSELUP00000013789Reticulon. (192 aa)
AXIN2Axin 2. (811 aa)
trib2Tribbles pseudokinase 2. (344 aa)
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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