(3 nodes) Macropinocytosis network (Esox lucius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSELUP00000017121	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	LOC105017320	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (409 aa)
	LOC105013205	MAPK activated protein kinase 2b. (605 aa)

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSELUP00000017121	LOC105013205	ENSELUP00000017121	ENSELUP00000014316	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	MAPK activated protein kinase 2b.	0.978
ENSELUP00000017121	LOC105017320	ENSELUP00000017121	ENSELUP00000005312	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	0.901
LOC105013205	ENSELUP00000017121	ENSELUP00000014316	ENSELUP00000017121	MAPK activated protein kinase 2b.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.978
LOC105013205	LOC105017320	ENSELUP00000014316	ENSELUP00000005312	MAPK activated protein kinase 2b.	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	0.978
LOC105017320	ENSELUP00000017121	ENSELUP00000005312	ENSELUP00000017121	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.901
LOC105017320	LOC105013205	ENSELUP00000005312	ENSELUP00000014316	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	MAPK activated protein kinase 2b.	0.978