(36 nodes) Photoreceptor cell maintenance network (Esox lucius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSELUP00000034331	Uncharacterized protein. (2458 aa)
	ENSELUP00000029844	Uncharacterized protein. (799 aa)
	dctn2	Dynactin 2 (p50). (369 aa)
	cln8	CLN8 transmembrane ER and ERGIC protein. (283 aa)
	iqcb1	IQ motif containing B1. (606 aa)
	LOC105018671	Bardet-Biedl syndrome 4. (530 aa)
	bbs1	Bardet-Biedl syndrome 1. (587 aa)
	nrf1	Nuclear respiratory factor 1. (555 aa)
	BBS4	Bardet-Biedl syndrome 4. (546 aa)
	bsg	Basigin. (390 aa)
	emc3	ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
	mkks	McKusick-Kaufman syndrome. (654 aa)
	bbs10	Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (613 aa)
	rp2	Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. (373 aa)
	LOC105024267	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (415 aa)
	cep290	Centrosomal protein 290. (2285 aa)
	ercc6	Excision repair cross-complementation group 6. (1494 aa)
	cluap1	Clusterin associated protein 1. (440 aa)
	ENSELUP00000007652	Uncharacterized protein. (2385 aa)
	ENSELUP00000007088	Uncharacterized protein. (2070 aa)
	spata7	Spermatogenesis associated 7. (582 aa)
	LOC105019360	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (421 aa)
	lca5	Lebercilin LCA5. (767 aa)
	nxnl2	Thioredoxin domain-containing protein. (157 aa)
	ift172	Intraflagellar transport 172. (1749 aa)
	ENSELUP00000000536	Usher syndrome 2A (autosomal recessive, mild). (5044 aa)
	LOC105014149	Crumbs cell polarity complex component 2b. (1431 aa)
	bbs12	Bardet-Biedl syndrome 12. (645 aa)
	ENSELUP00000043094	Uncharacterized protein. (694 aa)
	usp45	Ubiquitin carboxyl-terminal hydrolase. (786 aa)
	crb1	Crumbs cell polarity complex component 1. (1327 aa)
	CRB2	Uncharacterized protein. (1477 aa)
	ush1c	Usher syndrome 1C. (603 aa)
	ift57	Intraflagellar transport 57 homolog (Chlamydomonas). (416 aa)
	NPHP4	Nephrocystin 4. (1491 aa)
	nxnl1	Nucleoredoxin like 1. (228 aa)

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS4	ENSELUP00000029844	ENSELUP00000023164	ENSELUP00000029844	Bardet-Biedl syndrome 4.	Uncharacterized protein.	0.440
BBS4	bbs1	ENSELUP00000023164	ENSELUP00000024667	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 1.	0.979
BBS4	bbs10	ENSELUP00000023164	ENSELUP00000017387	Bardet-Biedl syndrome 4.	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	0.546
BBS4	bbs12	ENSELUP00000023164	ENSELUP00000041408	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 12.	0.521
BBS4	cep290	ENSELUP00000023164	ENSELUP00000011253	Bardet-Biedl syndrome 4.	Centrosomal protein 290.	0.538
BBS4	cluap1	ENSELUP00000023164	ENSELUP00000008952	Bardet-Biedl syndrome 4.	Clusterin associated protein 1.	0.572
BBS4	ift172	ENSELUP00000023164	ENSELUP00000002207	Bardet-Biedl syndrome 4.	Intraflagellar transport 172.	0.584
BBS4	ift57	ENSELUP00000023164	ENSELUP00000037630	Bardet-Biedl syndrome 4.	Intraflagellar transport 57 homolog (Chlamydomonas).	0.676
ENSELUP00000000536	ENSELUP00000034331	ENSELUP00000000536	ENSELUP00000034331	Usher syndrome 2A (autosomal recessive, mild).	Uncharacterized protein.	0.571
ENSELUP00000000536	cep290	ENSELUP00000000536	ENSELUP00000011253	Usher syndrome 2A (autosomal recessive, mild).	Centrosomal protein 290.	0.544
ENSELUP00000000536	lca5	ENSELUP00000000536	ENSELUP00000004735	Usher syndrome 2A (autosomal recessive, mild).	Lebercilin LCA5.	0.589
ENSELUP00000000536	ush1c	ENSELUP00000000536	ENSELUP00000037993	Usher syndrome 2A (autosomal recessive, mild).	Usher syndrome 1C.	0.679
ENSELUP00000029844	BBS4	ENSELUP00000029844	ENSELUP00000023164	Uncharacterized protein.	Bardet-Biedl syndrome 4.	0.440
ENSELUP00000029844	LOC105018671	ENSELUP00000029844	ENSELUP00000025650	Uncharacterized protein.	Bardet-Biedl syndrome 4.	0.440
ENSELUP00000029844	ercc6	ENSELUP00000029844	ENSELUP00000009392	Uncharacterized protein.	Excision repair cross-complementation group 6.	0.728
ENSELUP00000034331	ENSELUP00000000536	ENSELUP00000034331	ENSELUP00000000536	Uncharacterized protein.	Usher syndrome 2A (autosomal recessive, mild).	0.571
LOC105018671	ENSELUP00000029844	ENSELUP00000025650	ENSELUP00000029844	Bardet-Biedl syndrome 4.	Uncharacterized protein.	0.440
LOC105018671	bbs1	ENSELUP00000025650	ENSELUP00000024667	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 1.	0.979
LOC105018671	bbs10	ENSELUP00000025650	ENSELUP00000017387	Bardet-Biedl syndrome 4.	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	0.546
LOC105018671	bbs12	ENSELUP00000025650	ENSELUP00000041408	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 12.	0.521