STRINGSTRING
tmem109 tmem109 chek2 chek2 atr atr zmpste24 zmpste24 kdm1a kdm1a atm atm elk1 elk1 LOC105007215 LOC105007215 ENSELUP00000032389 ENSELUP00000032389 wrn wrn xrcc6 xrcc6 map3k20 map3k20
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tmem109Uncharacterized protein. (229 aa)
chek2Checkpoint kinase 2. (513 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2563 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (466 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (825 aa)
atmNon-specific serine/threonine protein kinase. (3011 aa)
elk1ETS transcription factor ELK1. (481 aa)
LOC105007215Protein kinase domain-containing protein. (597 aa)
ENSELUP00000032389Uncharacterized protein. (476 aa)
wrnWRN RecQ like helicase. (1484 aa)
xrcc6X-ray repair complementing defective repair in Chinese hamster cells 6. (610 aa)
map3k20Uncharacterized protein. (860 aa)
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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