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| | aire | Autoimmune regulator. (445 aa) |
| | LOC105011230 | RAD50 homolog, double strand break repair protein. (1314 aa) |
| | LOC105022397 | DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1568 aa) |
| | smarcal1 | Uncharacterized protein; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (1041 aa) |
| | msh6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1387 aa) |
| | LOC105027427 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1577 aa) |
| | smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a. (1636 aa) |
| | polk | Polymerase (DNA directed) kappa. (913 aa) |
| | LOC105020774 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (266 aa) |
| | ercc6 | Excision repair cross-complementation group 6. (1494 aa) |
| | ENSELUP00000008653 | Uncharacterized protein. (305 aa) |
| | dhx36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1050 aa) |
| | LOC105007933 | Snf2-related CREBBP activator protein. (2881 aa) |
| | rad1 | Cell cycle checkpoint protein RAD1. (280 aa) |
| | LOC105025422 | Uncharacterized protein. (118 aa) |
| | ENSELUP00000008155 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (873 aa) |
| | rad51b | RAD51 paralog B. (378 aa) |
| | mettl4 | Methyltransferase like 4; Belongs to the MT-A70-like family. (463 aa) |
| | ENDOV | Endonuclease V. (296 aa) |
| | LOC105013139 | ATPase family AAA domain containing 5a. (1854 aa) |
| | ENSELUP00000007556 | Uncharacterized protein. (235 aa) |
| | ENSELUP00000007524 | Uncharacterized protein. (298 aa) |
| | ENSELUP00000007493 | Uncharacterized protein. (285 aa) |
| | ruvbl2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | LOC105018056 | DNA (cytosine-5-)-methyltransferase 3 alpha a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (686 aa) |
| | ercc6l | Excision repair cross-complementation group 6-like. (1302 aa) |
| | LOC105016382 | General transcription factor IIF, polypeptide 2b. (248 aa) |
| | polg2 | Polymerase (DNA directed), gamma 2, accessory subunit. (463 aa) |
| | mlh3 | MutL homolog 3 (E. coli). (1272 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (699 aa) |
| | ENSELUP00000005976 | BRCA1 interacting protein C-terminal helicase 1. (941 aa) |
| | xrcc3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (361 aa) |
| | LOC105010544 | PHD-type domain-containing protein. (1344 aa) |
| | lg04h11orf80 | Uncharacterized protein. (459 aa) |
| | ttf2 | Uncharacterized protein. (1098 aa) |
| | mcm6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | fan1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1105 aa) |
| | LOC105017359 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (754 aa) |
| | Atrx | ATRX chromatin remodeler. (2039 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa) |
| | knl1 | Knl1_RWD_C domain-containing protein. (1650 aa) |
| | helb | Helicase (DNA) B. (1242 aa) |
| | pld4 | Phospholipase D family member 4. (515 aa) |
| | rtel1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1198 aa) |
| | ENSELUP00000002257 | Uncharacterized protein. (1610 aa) |
| | neil1 | Nei-like DNA glycosylase 1. (399 aa) |
| | tdg | Thymine DNA glycosylase, tandem duplicate 1. (479 aa) |
| | polg | Polymerase (DNA directed), gamma. (1211 aa) |
| | pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1982 aa) |
| | gtf2f2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (275 aa) |
| | MPHOSPH9 | Uncharacterized protein. (1375 aa) |
| | LOC105013881 | DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1492 aa) |
| | msh2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (962 aa) |
| | n6amt1 | N-6 adenine-specific DNA methyltransferase 1. (213 aa) |
| | ENSELUP00000000495 | Helicase, POLQ like. (980 aa) |
| | ercc6l2 | Excision repair cross-complementation group 6-like 2. (1496 aa) |
| | RAD54L2 | RAD54 like 2. (1421 aa) |
| | dhx9 | DEAH (Asp-Glu-Ala-His) box helicase 9. (1270 aa) |
| | chd5 | Chromodomain helicase DNA binding protein 5. (1804 aa) |
| | ENSELUP00000032389 | Uncharacterized protein. (476 aa) |
| | twnk | Twinkle mtDNA helicase. (750 aa) |
| | mcm5 | DNA helicase; Belongs to the MCM family. (739 aa) |
| | msh5 | MutS homolog 5. (750 aa) |
| | LOC105026975 | Uncharacterized protein. (1586 aa) |
| | ENSELUP00000031830 | RAD54 like 2. (857 aa) |
| | polb | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (336 aa) |
| | LOC105019233 | Tyrosyl-DNA phosphodiesterase 2a. (432 aa) |
| | rad54b | RAD54 homolog B. (930 aa) |
| | mus81 | MUS81 structure-specific endonuclease subunit. (617 aa) |
| | top2b | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1612 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (812 aa) |
| | ENSELUP00000031341 | DNA polymerase. (1412 aa) |
| | bivm | Basic, immunoglobulin-like variable motif containing. (600 aa) |
| | polh | Polymerase (DNA directed), eta. (779 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | Exo5 | Exonuclease 5. (421 aa) |
| | ENSELUP00000030130 | Replication factor C subunit 1. (1033 aa) |
| | Lig4 | DNA ligase. (912 aa) |
| | ddx1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1. (741 aa) |
| | fbh1 | F-box DNA helicase 1. (1030 aa) |
| | chd9 | Chromodomain helicase DNA binding protein 9. (2517 aa) |
| | fto | FTO alpha-ketoglutarate dependent dioxygenase. (559 aa) |
| | ankle1 | Zgc:85936. (1233 aa) |
| | primpol | Primase and polymerase (DNA-directed). (592 aa) |
| | ENSELUP00000028183 | C2H2-type domain-containing protein. (1011 aa) |
| | ENSELUP00000028142 | Reverse transcriptase domain-containing protein. (934 aa) |
| | poll | Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (597 aa) |
| | LOC105021611 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2588 aa) |
| | ENSELUP00000027643 | Polymerase (DNA directed) nu. (719 aa) |
| | haus3 | HAUS augmin-like complex, subunit 3. (666 aa) |
| | ENSELUP00000027570 | Cryptochrome DASH. (440 aa) |
| | LOC105017441 | SET domain and mariner transposase fusion gene. (299 aa) |
| | LOC105009541 | Thymine DNA glycosylase, tandem duplicate 2. (440 aa) |
| | LOC105029149 | Phospholipase D family, member 7. (847 aa) |
| | ercc3 | Excision repair cross-complementation group 3. (785 aa) |
| | LOC105013882 | DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (830 aa) |
| | ENSELUP00000026612 | Excision repair cross-complementation group 5. (1138 aa) |
| | LOC105026399 | DNA helicase; Belongs to the MCM family. (813 aa) |
| | LOC105013965 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (766 aa) |
| | rad9a | RAD9 checkpoint clamp component A. (352 aa) |
| | LOC105010844 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (246 aa) |
| | LOC105028924 | Zgc:66475. (550 aa) |
| | chd7 | Chromodomain helicase DNA binding protein 7. (2804 aa) |
| | Msh3 | MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR). (931 aa) |
| | ENSELUP00000025085 | Uncharacterized protein. (160 aa) |
| | dnmt1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1530 aa) |
| | ascc3 | Activating signal cointegrator 1 complex subunit 3. (2212 aa) |
| | ENSELUP00000024408 | Uncharacterized protein. (1479 aa) |
| | smc3 | Structural maintenance of chromosomes protein. (1216 aa) |
| | top3b | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (845 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (660 aa) |
| | recql4 | RecQ helicase-like 4. (1558 aa) |
| | mpg | N-methylpurine DNA glycosylase. (276 aa) |
| | apex1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (312 aa) |
| | ddx11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (900 aa) |
| | apex2 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (582 aa) |
| | LOC105025851 | Chromodomain helicase DNA binding protein 4a. (1825 aa) |
| | mcm9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1418 aa) |
| | alkbh2 | AlkB homolog 2, alpha-ketoglutarate-dependent dioxygenase. (263 aa) |
| | ung | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (303 aa) |
| | rad51c | RAD51 paralog C. (359 aa) |
| | hmga2 | High mobility group AT-hook 2. (112 aa) |
| | mlh1 | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (715 aa) |
| | APLF | Aprataxin and PNKP like factor. (513 aa) |
| | recql | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (834 aa) |
| | top2a | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1504 aa) |
| | LOC105027758 | Deoxyribonuclease; Belongs to the DNase I family. (309 aa) |
| | dclre1c | DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (696 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (702 aa) |
| | LOC105028962 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1021 aa) |
| | rad54l | RAD54 like. (745 aa) |
| | ENSELUP00000042106 | Immunoglobulin mu DNA binding protein 2. (965 aa) |
| | ogg1 | 8-oxoguanine DNA glycosylase. (407 aa) |
| | polm | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (531 aa) |
| | dicer1 | Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1865 aa) |
| | LOC105015448 | DNA (cytosine-5-)-methyltransferase 3 alpha b; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1029 aa) |
| | rad9b | RAD9 checkpoint clamp component B. (383 aa) |
| | mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (730 aa) |
| | dclre1a | DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (950 aa) |
| | dnase2 | Deoxyribonuclease II, lysosomal. (405 aa) |
| | alkbh4 | AlkB homolog 4, lysine demthylase. (270 aa) |
| | mgme1 | Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family. (343 aa) |
| | pld3 | Phospholipase D family, member 3. (485 aa) |
| | ENSELUP00000033878 | Chromodomain helicase DNA binding protein 6. (2063 aa) |
| | lig1 | DNA ligase. (1069 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1033 aa) |
| | ENSELUP00000035354 | DNA cross-link repair 1B. (598 aa) |
| | dkc1 | Dyskeratosis congenita 1, dyskerin. (507 aa) |
| | pgbd5 | PiggyBac transposable element derived 5. (519 aa) |
| | DNASE1L3 | Deoxyribonuclease 1 like 3. (331 aa) |
| | ENSELUP00000021469 | INO80 complex ATPase subunit. (1485 aa) |
| | ENSELUP00000021334 | E1A binding protein p400. (2826 aa) |
| | cry1 | Cryptochrome circadian regulator 1b. (565 aa) |
| | Aptx | FHA_2 domain-containing protein. (82 aa) |
| | rexo2 | Small fragment nuclease. (289 aa) |
| | wrnip1 | WRN helicase interacting protein 1. (615 aa) |
| | ENSELUP00000020281 | Uncharacterized protein. (117 aa) |
| | pif1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (682 aa) |
| | LOC105025728 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (834 aa) |
| | lig3 | DNA ligase. (1020 aa) |
| | rad51d | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (335 aa) |
| | LOC105014983 | Uncharacterized protein. (981 aa) |
| | ercc4 | Excision repair cross-complementation group 4. (892 aa) |
| | blm | BLM RecQ like helicase. (1473 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (887 aa) |
| | dntt | DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (499 aa) |
| | LOC105015403 | Structural maintenance of chromosomes 6. (1082 aa) |
| | Hfm1 | Helicase for meiosis 1. (933 aa) |
| | meiob | Methionine sulfoxide reductase B1b. (471 aa) |
| | supv3l1 | SUV3-like helicase. (779 aa) |
| | smarcad1 | Uncharacterized protein. (1017 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1421 aa) |
| | ENSELUP00000018876 | REV3 like, DNA directed polymerase zeta catalytic subunit. (2835 aa) |
| | EXOG | Exo/endonuclease G. (362 aa) |
| | ENSELUP00000018284 | Endo/exonuclease/phosphatase domain-containing protein. (185 aa) |
| | chd1 | Chromodomain helicase DNA binding protein 1. (1821 aa) |
| | tatdn1 | TatD DNase domain containing 1. (323 aa) |
| | LOC105011061 | Remodeling and spacing factor 1b, tandem duplicate 1. (1807 aa) |
| | LOC105011047 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (245 aa) |
| | dffb | CIDE-N domain-containing protein. (335 aa) |
| | XRCC2 | X-ray repair cross complementing 2. (316 aa) |
| | nthl1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (439 aa) |
| | spo11 | SPO11 initiator of meiotic double stranded breaks. (428 aa) |
| | ENSELUP00000016759 | Uncharacterized protein. (101 aa) |
| | tdp2 | Tyrosyl-DNA phosphodiesterase 2b. (380 aa) |
| | LOC105024976 | Zgc:110269. (350 aa) |
| | ENSELUP00000015834 | Uncharacterized protein. (1794 aa) |
| | tert | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1129 aa) |
| | LOC105018596 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (562 aa) |
| | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (982 aa) |
| | LOC105024246 | DNA helicase; Belongs to the MCM family. (823 aa) |
| | zranb3 | Zinc finger, RAN-binding domain containing 3. (1168 aa) |
| | exo1 | Exonuclease 1. (801 aa) |
| | pms1 | PMS1 homolog 1, mismatch repair system component. (911 aa) |
| | kiaa1257 | Si:dkey-57n24.6. (1212 aa) |
| | dnase1 | Deoxyribonuclease; Belongs to the DNase I family. (286 aa) |
| | mcm8 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (820 aa) |
| | pold1 | DNA polymerase. (1105 aa) |
| | hells | Helicase, lymphoid specific. (856 aa) |
| | hltf | Helicase-like transcription factor. (952 aa) |
| | MUTYH | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (522 aa) |
| | endog | Endonuclease. (310 aa) |
| | ruvbl1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | ENSELUP00000037121 | Chromodomain helicase DNA binding protein 1-like. (980 aa) |
| | LOC105013490 | Deoxyribonuclease; Belongs to the DNase I family. (296 aa) |
| | alkbh1 | AlkB homolog 1, histone H2A dioxygenase. (405 aa) |
| | recql5 | RecQ helicase-like 5. (1029 aa) |
| | wrn | WRN RecQ like helicase. (1484 aa) |
| | chd2 | Chromodomain helicase DNA binding protein 2. (1824 aa) |
| | pms2 | PMS1 homolog 2, mismatch repair system component. (918 aa) |
| | tdp1 | Tyrosyl-DNA phosphodiesterase 1. (629 aa) |
| | ercc2 | Excision repair cross-complementation group 2. (760 aa) |
| | ENSELUP00000038206 | Uncharacterized protein. (1826 aa) |
| | gen1 | Uncharacterized protein. (1014 aa) |
| | smc6 | Si:dkey-119f1.1. (1078 aa) |
| | LOC105018167 | CECR2 histone acetyl-lysine reader. (1194 aa) |
| | ENSELUP00000038519 | Polymerase (DNA directed), theta. (1575 aa) |
| | mbd4 | MBD domain-containing protein. (589 aa) |
| | btaf1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated. (1834 aa) |
| | shprh | SNF2 histone linker PHD RING helicase. (1626 aa) |
| | dmc1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (342 aa) |
| | ENSELUP00000039300 | Uncharacterized protein. (94 aa) |
| | ENSELUP00000039322 | Chromodomain helicase DNA binding protein 3. (1567 aa) |
| | smug1 | Single-strand-selective monofunctional uracil-DNA glycosylase 1. (337 aa) |
| | Rev1 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (917 aa) |
| | xrcc6 | X-ray repair complementing defective repair in Chinese hamster cells 6. (610 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | DNASE1L1 | Deoxyribonuclease; Belongs to the DNase I family. (270 aa) |
| | neil3 | Nei-like DNA glycosylase 3. (610 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (858 aa) |
