38 items (Esox lucius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	chtf8	CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (125 aa)
	dkc1	Dyskeratosis congenita 1, dyskerin. (507 aa)
	nox4	FAD-binding FR-type domain-containing protein. (559 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (439 aa)
	gins3	GINS complex subunit 3. (200 aa)
	rfc4	Replication factor C (activator 1) 4. (376 aa)
	CCT3	T-complex protein 1 subunit gamma. (540 aa)
	pnkp	Polynucleotide kinase 3'-phosphatase. (612 aa)
	polg2	Polymerase (DNA directed), gamma 2, accessory subunit. (463 aa)
	atr	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2563 aa)
	GREM1	Gremlin. (183 aa)
	pot1	Protection of telomeres 1 homolog. (802 aa)
	gins2	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
	ENSELUP00000032389	Uncharacterized protein. (476 aa)
	ENSELUP00000004013	Uncharacterized protein. (335 aa)
	HMBOX1	Homeobox containing 1. (279 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	fbxo4	F-box protein 4. (382 aa)
	wrap53	WD repeat containing, antisense to TP53. (554 aa)
	LOC105012081	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (585 aa)
	cct2	Chaperonin containing TCP1, subunit 2 (beta). (424 aa)
	atm	Non-specific serine/threonine protein kinase. (3011 aa)
	rgcc	Uncharacterized protein. (130 aa)
	gins4	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (225 aa)
	ENSELUP00000017019	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (806 aa)
	LOC105012686	T-complex protein 1 subunit gamma. (540 aa)
	mapkapk5	MAPK activated protein kinase 5. (471 aa)
	rfc2	Replication factor C (activator 1) 2. (368 aa)
	nek2	NIMA-related kinase 2. (449 aa)
	LOC105031171	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (521 aa)
	rfc5	AAA domain-containing protein. (335 aa)
	ENSELUP00000003976	Cytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family. (526 aa)
	cct5	Chaperonin containing TCP1, subunit 5 (epsilon). (541 aa)
	nvl	Nuclear VCP like. (888 aa)
	gfer	Sulfhydryl oxidase. (213 aa)
	LOC105016238	Uncharacterized protein. (610 aa)
	map3k4	Mitogen-activated protein kinase kinase kinase 4. (1683 aa)
	LOC105029712	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (531 aa)

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCT3	cct2	ENSELUP00000008206	ENSELUP00000011299	T-complex protein 1 subunit gamma.	Chaperonin containing TCP1, subunit 2 (beta).	0.996
CCT3	cct5	ENSELUP00000008206	ENSELUP00000000470	T-complex protein 1 subunit gamma.	Chaperonin containing TCP1, subunit 5 (epsilon).	0.996
ENSELUP00000017019	atr	ENSELUP00000017019	ENSELUP00000006242	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae).	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.670
ENSELUP00000017019	chtf8	ENSELUP00000017019	ENSELUP00000035560	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae).	CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae).	0.997
ENSELUP00000017019	gins4	ENSELUP00000017019	ENSELUP00000017159	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae).	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.	0.457
ENSELUP00000017019	rfc2	ENSELUP00000017019	ENSELUP00000014257	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae).	Replication factor C (activator 1) 2.	0.987
ENSELUP00000017019	rfc3	ENSELUP00000017019	ENSELUP00000030603	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae).	Replication factor C (activator 1) 3.	0.989
ENSELUP00000017019	rfc4	ENSELUP00000017019	ENSELUP00000008564	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae).	Replication factor C (activator 1) 4.	0.988
ENSELUP00000017019	rfc5	ENSELUP00000017019	ENSELUP00000003484	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae).	AAA domain-containing protein.	0.989
ENSELUP00000032389	atm	ENSELUP00000032389	ENSELUP00000019434	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.944
ENSELUP00000032389	atr	ENSELUP00000032389	ENSELUP00000006242	Uncharacterized protein.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.687
ENSELUP00000032389	gins3	ENSELUP00000032389	ENSELUP00000033152	Uncharacterized protein.	GINS complex subunit 3.	0.549
ENSELUP00000032389	pnkp	ENSELUP00000032389	ENSELUP00000007979	Uncharacterized protein.	Polynucleotide kinase 3'-phosphatase.	0.582
ENSELUP00000032389	rfc2	ENSELUP00000032389	ENSELUP00000014257	Uncharacterized protein.	Replication factor C (activator 1) 2.	0.423
ENSELUP00000032389	rfc4	ENSELUP00000032389	ENSELUP00000008564	Uncharacterized protein.	Replication factor C (activator 1) 4.	0.511
ENSELUP00000032389	rfc5	ENSELUP00000032389	ENSELUP00000003484	Uncharacterized protein.	AAA domain-containing protein.	0.452
LOC105012686	cct2	ENSELUP00000016725	ENSELUP00000011299	T-complex protein 1 subunit gamma.	Chaperonin containing TCP1, subunit 2 (beta).	0.996
LOC105012686	cct5	ENSELUP00000016725	ENSELUP00000000470	T-complex protein 1 subunit gamma.	Chaperonin containing TCP1, subunit 5 (epsilon).	0.996
LOC105016238	dkc1	ENSELUP00000011514	ENSELUP00000035518	Uncharacterized protein.	Dyskeratosis congenita 1, dyskerin.	0.659
LOC105016238	pot1	ENSELUP00000011514	ENSELUP00000004177	Uncharacterized protein.	Protection of telomeres 1 homolog.	0.990