5 items (Esox lucius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rad9a	RAD9 checkpoint clamp component A. (352 aa)
	cdca7	Cell division cycle associated 7a. (419 aa)
	hus1	Checkpoint protein; Belongs to the HUS1 family. (283 aa)
	rad1	Cell cycle checkpoint protein RAD1. (280 aa)
	rad9b	RAD9 checkpoint clamp component B. (383 aa)

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cdca7	hus1	ENSELUP00000023624	ENSELUP00000016476	Cell division cycle associated 7a.	Checkpoint protein; Belongs to the HUS1 family.	0.955
cdca7	rad1	ENSELUP00000023624	ENSELUP00000008354	Cell division cycle associated 7a.	Cell cycle checkpoint protein RAD1.	0.955
hus1	cdca7	ENSELUP00000016476	ENSELUP00000023624	Checkpoint protein; Belongs to the HUS1 family.	Cell division cycle associated 7a.	0.955
hus1	rad1	ENSELUP00000016476	ENSELUP00000008354	Checkpoint protein; Belongs to the HUS1 family.	Cell cycle checkpoint protein RAD1.	0.999
hus1	rad9a	ENSELUP00000016476	ENSELUP00000025909	Checkpoint protein; Belongs to the HUS1 family.	RAD9 checkpoint clamp component A.	0.978
hus1	rad9b	ENSELUP00000016476	ENSELUP00000043031	Checkpoint protein; Belongs to the HUS1 family.	RAD9 checkpoint clamp component B.	0.993
rad1	cdca7	ENSELUP00000008354	ENSELUP00000023624	Cell cycle checkpoint protein RAD1.	Cell division cycle associated 7a.	0.955
rad1	hus1	ENSELUP00000008354	ENSELUP00000016476	Cell cycle checkpoint protein RAD1.	Checkpoint protein; Belongs to the HUS1 family.	0.999
rad1	rad9a	ENSELUP00000008354	ENSELUP00000025909	Cell cycle checkpoint protein RAD1.	RAD9 checkpoint clamp component A.	0.979
rad1	rad9b	ENSELUP00000008354	ENSELUP00000043031	Cell cycle checkpoint protein RAD1.	RAD9 checkpoint clamp component B.	0.997
rad9a	hus1	ENSELUP00000025909	ENSELUP00000016476	RAD9 checkpoint clamp component A.	Checkpoint protein; Belongs to the HUS1 family.	0.978
rad9a	rad1	ENSELUP00000025909	ENSELUP00000008354	RAD9 checkpoint clamp component A.	Cell cycle checkpoint protein RAD1.	0.979
rad9a	rad9b	ENSELUP00000025909	ENSELUP00000043031	RAD9 checkpoint clamp component A.	RAD9 checkpoint clamp component B.	0.407
rad9b	hus1	ENSELUP00000043031	ENSELUP00000016476	RAD9 checkpoint clamp component B.	Checkpoint protein; Belongs to the HUS1 family.	0.993
rad9b	rad1	ENSELUP00000043031	ENSELUP00000008354	RAD9 checkpoint clamp component B.	Cell cycle checkpoint protein RAD1.	0.997
rad9b	rad9a	ENSELUP00000043031	ENSELUP00000025909	RAD9 checkpoint clamp component B.	RAD9 checkpoint clamp component A.	0.407