31 items (Esox lucius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	wfikkn2	Info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a. (579 aa)
	pcolce2	Procollagen C-endopeptidase enhancer 2b. (433 aa)
	ENSELUP00000001668	Netrin 4. (558 aa)
	sfrp2	Secreted frizzled-related protein 2. (292 aa)
	ntn1	Netrin 1a. (603 aa)
	LOC105018835	Complement 4B (Chido blood group). (1725 aa)
	LOC105010521	Complement component 4. (1645 aa)
	NTN4	Netrin 4. (733 aa)
	LOC105030962	Netrin 2. (638 aa)
	LOC105013164	Netrin 1b. (600 aa)
	c5	Complement component 5. (1694 aa)
	frzb	Frizzled related protein. (317 aa)
	LOC105024057	Uncharacterized protein. (324 aa)
	LOC105013051	TIMP metallopeptidase inhibitor 2b. (219 aa)
	LOC105024596	Procollagen C-endopeptidase enhancer a. (490 aa)
	lg09h17orf58	NTR domain-containing protein. (384 aa)
	ENSELUP00000018133	Anaphylatoxin-like domain-containing protein. (1585 aa)
	timp2	TIMP metallopeptidase inhibitor 2a. (219 aa)
	LOC105031491	Netrin 5. (858 aa)
	sfrp5	Secreted frizzled-related protein 5. (327 aa)
	adamtsl5	ADAMTS like 5. (556 aa)
	LOC105013878	Uncharacterized protein. (370 aa)
	wfikkn1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (616 aa)
	LOC105017322	Si:dkey-202e22.2. (608 aa)
	LOC105026632	Sizzled. (266 aa)
	LOC105020777	Procollagen C-endopeptidase enhancer b. (640 aa)
	TIMP3	TIMP metallopeptidase inhibitor 3. (214 aa)
	ENSELUP00000036044	Complement component c3a, duplicate 2. (1566 aa)
	ENSELUP00000037927	Anaphylatoxin-like domain-containing protein. (1670 aa)
	LOC105025054	Uncharacterized protein. (578 aa)
	ENSELUP00000041238	Complement component c3b, tandem duplicate 2. (1719 aa)

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSELUP00000018133	c5	ENSELUP00000018133	ENSELUP00000009299	Anaphylatoxin-like domain-containing protein.	Complement component 5.	0.548
ENSELUP00000036044	c5	ENSELUP00000036044	ENSELUP00000009299	Complement component c3a, duplicate 2.	Complement component 5.	0.548
ENSELUP00000037927	c5	ENSELUP00000037927	ENSELUP00000009299	Anaphylatoxin-like domain-containing protein.	Complement component 5.	0.952
ENSELUP00000041238	c5	ENSELUP00000041238	ENSELUP00000009299	Complement component c3b, tandem duplicate 2.	Complement component 5.	0.548
LOC105010521	c5	ENSELUP00000005682	ENSELUP00000009299	Complement component 4.	Complement component 5.	0.548
LOC105013051	TIMP3	ENSELUP00000013965	ENSELUP00000034857	TIMP metallopeptidase inhibitor 2b.	TIMP metallopeptidase inhibitor 3.	0.511
LOC105018835	c5	ENSELUP00000005423	ENSELUP00000009299	Complement 4B (Chido blood group).	Complement component 5.	0.548
TIMP3	LOC105013051	ENSELUP00000034857	ENSELUP00000013965	TIMP metallopeptidase inhibitor 3.	TIMP metallopeptidase inhibitor 2b.	0.511
TIMP3	timp2	ENSELUP00000034857	ENSELUP00000018652	TIMP metallopeptidase inhibitor 3.	TIMP metallopeptidase inhibitor 2a.	0.503
c5	ENSELUP00000018133	ENSELUP00000009299	ENSELUP00000018133	Complement component 5.	Anaphylatoxin-like domain-containing protein.	0.548
c5	ENSELUP00000036044	ENSELUP00000009299	ENSELUP00000036044	Complement component 5.	Complement component c3a, duplicate 2.	0.548
c5	ENSELUP00000037927	ENSELUP00000009299	ENSELUP00000037927	Complement component 5.	Anaphylatoxin-like domain-containing protein.	0.952
c5	ENSELUP00000041238	ENSELUP00000009299	ENSELUP00000041238	Complement component 5.	Complement component c3b, tandem duplicate 2.	0.548
c5	LOC105010521	ENSELUP00000009299	ENSELUP00000005682	Complement component 5.	Complement component 4.	0.548
c5	LOC105018835	ENSELUP00000009299	ENSELUP00000005423	Complement component 5.	Complement 4B (Chido blood group).	0.548
sfrp2	sfrp5	ENSELUP00000002664	ENSELUP00000022933	Secreted frizzled-related protein 2.	Secreted frizzled-related protein 5.	0.908
sfrp5	sfrp2	ENSELUP00000022933	ENSELUP00000002664	Secreted frizzled-related protein 5.	Secreted frizzled-related protein 2.	0.908
timp2	TIMP3	ENSELUP00000018652	ENSELUP00000034857	TIMP metallopeptidase inhibitor 2a.	TIMP metallopeptidase inhibitor 3.	0.503