STRINGSTRING
pold2 pold2 rfc5 rfc5 stn1 stn1 pot1 pot1 ten1 ten1 pcna pcna rfc4 rfc4 LOC105016238 LOC105016238 pold1 pold1 rfc2 rfc2 ENSELUP00000016298 ENSELUP00000016298 ENSELUP00000017019 ENSELUP00000017019 pold3 pold3 pold4 pold4 prim2 prim2 LOC105006037 LOC105006037 dscc1 dscc1 tinf2 tinf2 LOC105019838 LOC105019838 pola2 pola2 ENSELUP00000030130 ENSELUP00000030130 terf1 terf1 rfc3 rfc3 ENSELUP00000031341 ENSELUP00000031341 chtf8 chtf8 prim1 prim1 RCBTB1 RCBTB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (473 aa)
rfc5AAA domain-containing protein. (335 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (381 aa)
pot1Protection of telomeres 1 homolog. (802 aa)
ten1TEN1 subunit of CST complex. (145 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
rfc4Replication factor C (activator 1) 4. (376 aa)
LOC105016238Uncharacterized protein. (610 aa)
pold1DNA polymerase. (1105 aa)
rfc2Replication factor C (activator 1) 2. (368 aa)
ENSELUP00000016298Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (438 aa)
ENSELUP00000017019CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (806 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (450 aa)
pold4Si:dkey-28b4.7. (109 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (520 aa)
LOC105006037Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (520 aa)
dscc1DNA replication and sister chromatid cohesion 1. (394 aa)
tinf2TERF1 (TRF1)-interacting nuclear factor 2. (590 aa)
LOC105019838Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (583 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (608 aa)
ENSELUP00000030130Replication factor C subunit 1. (1033 aa)
terf1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (382 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
ENSELUP00000031341DNA polymerase. (1412 aa)
chtf8CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (125 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (418 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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