STRINGSTRING
txndc11 txndc11 LOC105013196 LOC105013196 ENSELUP00000035618 ENSELUP00000035618 LOC105011486 LOC105011486 ENSELUP00000000127 ENSELUP00000000127 LOC105019735 LOC105019735 tp53inp2 tp53inp2 LOC105014136 LOC105014136 LOC105013872 LOC105013872 rmi1 rmi1 banp banp ENSELUP00000001840 ENSELUP00000001840 chek2 chek2 prkaa1 prkaa1 taf7l taf7l LOC105020246 LOC105020246 LOC105020226 LOC105020226 rps27a rps27a akt1 akt1 LOC105023581 LOC105023581 ENSELUP00000003468 ENSELUP00000003468 rfc5 rfc5 prmt5 prmt5 AKT1 AKT1 mtor mtor rad9b rad9b ssrp1 ssrp1 brd9 brd9 LOC105025176 LOC105025176 ENSELUP00000042554 ENSELUP00000042554 taf2 taf2 ENSELUP00000042351 ENSELUP00000042351 hipk3 hipk3 ccng1 ccng1 LOC105014211 LOC105014211 rpa3 rpa3 LOC105011230 LOC105011230 aire aire cdk5 cdk5 Ppp1r13l Ppp1r13l pwwp2a pwwp2a LOC105031589 LOC105031589 cdk2 cdk2 snn-2 snn-2 LOC105022876 LOC105022876 LOC105016973 LOC105016973 ENSELUP00000039672 ENSELUP00000039672 STK11 STK11 ENSELUP00000039322 ENSELUP00000039322 hipk2 hipk2 L3MBTL4 L3MBTL4 LOC105028325 LOC105028325 Znf385c Znf385c brpf1 brpf1 LOC105018106 LOC105018106 ENSELUP00000038206 ENSELUP00000038206 wrn wrn ENSELUP00000037811 ENSELUP00000037811 Slf1 Slf1 RBBP4 RBBP4 kat5 kat5 LOC105009343 LOC105009343 LOC105030312 LOC105030312 LOC105008394 LOC105008394 Mapkap1 Mapkap1 LOC105008396 LOC105008396 LOC105013663 LOC105013663 kxd1 kxd1 cdk1 cdk1 tp73 tp73 LOC105017338 LOC105017338 csnk2b csnk2b ppp1r13b ppp1r13b taf10 taf10 prkaa2 prkaa2 JMY JMY brd7 brd7 ankrd12 ankrd12 prkag1 prkag1 LOC105007766 LOC105007766 brca1 brca1 rad17 rad17 ENSELUP00000006184 ENSELUP00000006184 atr atr LOC105028035 LOC105028035 taf3 taf3 topbp1 topbp1 tp63 tp63 ccna1 ccna1 noc2l noc2l tp53bp2 tp53bp2 brd1 brd1 rad1 rad1 rfc4 rfc4 PIP4K2B PIP4K2B nuak1 nuak1 LOC105018928 LOC105018928 pdpk1 pdpk1 taf13 taf13 PRKAB2 PRKAB2 LOC105027634 LOC105027634 mre11 mre11 znf385b znf385b nbn nbn LOC105024892 LOC105024892 taf5l taf5l csnk2a2 csnk2a2 pip4k2a pip4k2a Pin1 Pin1 mdm4 mdm4 pip4p1 pip4p1 LOC105023872 LOC105023872 HIPK4 HIPK4 LOC105021541 LOC105021541 LOC105016722 LOC105016722 dyrk2 dyrk2 LOC105026340 LOC105026340 akt3 akt3 usp7 usp7 mdm2 mdm2 dyrk4 dyrk4 exo1 exo1 nuak2 nuak2 gatad2b gatad2b ing5 ing5 tp53rk tp53rk LOC105026211 LOC105026211 akt2 akt2 top3a top3a LOC105023895 LOC105023895 LOC105027970 LOC105027970 LOC105023001 LOC105023001 LOC105024120 LOC105024120 LOC105007115 LOC105007115 rbbp7 rbbp7 chd5 chd5 prdm1 prdm1 LOC105020732 LOC105020732 LOC105020742 LOC105020742 tp53inp1 tp53inp1 LOC105013538 LOC105013538 ehmt1 ehmt1 LOC105020679 LOC105020679 ENSELUP00000031146 ENSELUP00000031146 LOC105031058 LOC105031058 LOC105030639 LOC105030639 LOC105007380 LOC105007380 PPP2CB PPP2CB rfc3 rfc3 taf6 taf6 meaf6 meaf6 taf1 taf1 tpx2 tpx2 pip4k2c pip4k2c ENSELUP00000029992 ENSELUP00000029992 LOC105007983 LOC105007983 SGK1 SGK1 tbpl1 tbpl1 kat6a kat6a LOC105023927 LOC105023927 LOC105028498 LOC105028498 taf9 taf9 ehmt2 ehmt2 LOC105018845 LOC105018845 brpf3 brpf3 LOC105017349 LOC105017349 taf5 taf5 ing1 ing1 LOC105015627 LOC105015627 LOC105014416 LOC105014416 pou4f1 pou4f1 LOC105024716 LOC105024716 LOC105026040 LOC105026040 kmt5a kmt5a TAF4B TAF4B rhno1 rhno1 LOC105008589 LOC105008589 setd9 setd9 rad9a rad9a ttc5 ttc5 LOC105008788 LOC105008788 LOC105024916 LOC105024916 tdrd3 tdrd3 pou4f3 pou4f3 LOC105028830 LOC105028830 LOC105026079 LOC105026079 rnf34 rnf34 LOC105028429 LOC105028429 cdca7 cdca7 exd2 exd2 recql4 recql4 LOC105022821 LOC105022821 LOC105023716 LOC105023716 ENSELUP00000022356 ENSELUP00000022356 LOC105031018 LOC105031018 LOC105025851 LOC105025851 rpa1 rpa1 LOC105026695 LOC105026695 LOC105024444 LOC105024444 LOC105014886 LOC105014886 LOC105025106 LOC105025106 l3mbtl3 l3mbtl3 mapkapk5 mapkapk5 LOC105007426 LOC105007426 ENSELUP00000020288 ENSELUP00000020288 ENSELUP00000020281 ENSELUP00000020281 aurka aurka blm blm taf11 taf11 atm atm mlst8 mlst8 meiob meiob rpa2 rpa2 DNA2 DNA2 LOC105010739 LOC105010739 ankrd11 ankrd11 LOC105014960 LOC105014960 LOC105021738 LOC105021738 LOC105018996 LOC105018996 LOC105012352 LOC105012352 LOC105027313 LOC105027313 rffl rffl pip4p2 pip4p2 TAF4 TAF4 hus1 hus1 LOC105021685 LOC105021685 taf12 taf12 ZNF385A ZNF385A atrip atrip pou4f2 pou4f2 LOC105023970 LOC105023970 rfc2 rfc2 ENSELUP00000014319 ENSELUP00000014319 tbp tbp LOC105026110 LOC105026110
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
txndc11Thioredoxin domain containing 11. (898 aa)
LOC105013196Protein kinase domain-containing protein. (618 aa)
ENSELUP00000035618Cyclin-dependent kinase 5, regulatory subunit 2b (p39). (333 aa)
LOC105011486Protein phosphatase 2, regulatory subunit A, beta b. (595 aa)
ENSELUP00000000127Uncharacterized protein. (78 aa)
LOC105019735Cyclin-dependent kinase 5 activator. (320 aa)
tp53inp2Uncharacterized protein. (311 aa)
LOC105014136Euchromatic histone-lysine N-methyltransferase 1a. (858 aa)
LOC105013872Si:ch211-117c9.1. (702 aa)
rmi1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (573 aa)
banpBTG3 associated nuclear protein. (509 aa)
ENSELUP00000001840Checkpoint kinase 1. (382 aa)
chek2Checkpoint kinase 2. (513 aa)
prkaa1Non-specific serine/threonine protein kinase. (579 aa)
taf7lTAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (371 aa)
LOC105020246Protein kinase domain-containing protein. (607 aa)
LOC105020226Mitogen-activated protein kinase. (361 aa)
rps27aRibosomal protein S27a. (177 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)
LOC105023581Protein phosphatase 1, regulatory subunit 13Ba. (1119 aa)
ENSELUP00000003468Ubiquitin-like domain-containing protein. (86 aa)
rfc5AAA domain-containing protein. (335 aa)
prmt5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (645 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (474 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2514 aa)
rad9bRAD9 checkpoint clamp component B. (383 aa)
ssrp1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (707 aa)
brd9Bromodomain containing 9. (690 aa)
LOC105025176RPTOR independent companion of MTOR, complex 2b. (1530 aa)
ENSELUP00000042554RICTOR_N domain-containing protein. (160 aa)
taf2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1219 aa)
ENSELUP00000042351Uncharacterized protein. (69 aa)
hipk3Homeodomain interacting protein kinase 3b. (1362 aa)
ccng1Cyclin G1; Belongs to the cyclin family. (299 aa)
LOC105014211Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (270 aa)
rpa3Uncharacterized protein. (121 aa)
LOC105011230RAD50 homolog, double strand break repair protein. (1314 aa)
aireAutoimmune regulator. (445 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
Ppp1r13lProtein phosphatase 1, regulatory subunit 13 like. (965 aa)
pwwp2aPWWP domain containing 2A. (1026 aa)
LOC105031589Retinoblastoma binding protein 8. (690 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (301 aa)
snn-2RecQ mediated genome instability 2. (159 aa)
LOC105022876FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (654 aa)
LOC105016973Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b. (461 aa)
ENSELUP00000039672GATA zinc finger domain containing 2Ab. (534 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (428 aa)
ENSELUP00000039322Chromodomain helicase DNA binding protein 3. (1567 aa)
hipk2Homeodomain interacting protein kinase 2. (1253 aa)
L3MBTL4L3MBTL histone methyl-lysine binding protein 4. (526 aa)
LOC105028325Uncharacterized protein. (472 aa)
Znf385cZinc finger protein 385C. (533 aa)
brpf1Uncharacterized protein. (1351 aa)
LOC105018106Si:dkey-219c3.2. (1006 aa)
ENSELUP00000038206Uncharacterized protein. (1826 aa)
wrnWRN RecQ like helicase. (1484 aa)
ENSELUP00000037811BRCT domain-containing protein. (139 aa)
Slf1ANK_REP_REGION domain-containing protein. (352 aa)
RBBP4RB binding protein 4, chromatin remodeling factor. (448 aa)
kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (655 aa)
LOC105009343Bromodomain containing 1b. (1187 aa)
LOC105030312Homeodomain interacting protein kinase 3a. (1211 aa)
LOC105008394Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (348 aa)
Mapkap1MAPK associated protein 1. (541 aa)
LOC105008396Si:ch211-160o17.4. (1164 aa)
LOC105013663Homeodomain interacting protein kinase 1a. (1167 aa)
kxd1KxDL motif containing 1. (187 aa)
cdk1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
tp73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (677 aa)
LOC105017338TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor. (825 aa)
csnk2bCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
ppp1r13bProtein phosphatase 1, regulatory subunit 13Bb. (1094 aa)
taf10Uncharacterized protein. (196 aa)
prkaa2Non-specific serine/threonine protein kinase. (596 aa)
JMYJunction mediating and regulatory protein, p53 cofactor. (919 aa)
brd7Bromodomain containing 7. (636 aa)
ankrd12Ankyrin repeat domain 12. (2110 aa)
prkag1Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (332 aa)
LOC105007766Uncharacterized protein. (536 aa)
brca1Uncharacterized protein. (1565 aa)
rad17RAD17 checkpoint clamp loader component. (699 aa)
ENSELUP00000006184TAF4 domain-containing protein. (212 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2563 aa)
LOC105028035Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (955 aa)
topbp1DNA topoisomerase II binding protein 1. (1493 aa)
tp63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (598 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (405 aa)
noc2lNOC2-like nucleolar associated transcriptional repressor. (757 aa)
tp53bp2Tumor protein p53 binding protein, 2a. (1201 aa)
brd1Bromodomain containing 1a. (1232 aa)
rad1Cell cycle checkpoint protein RAD1. (280 aa)
rfc4Replication factor C (activator 1) 4. (376 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (429 aa)
nuak1NUAK family, SNF1-like kinase, 1b. (614 aa)
LOC105018928L3MBTL histone methyl-lysine binding protein 1b. (847 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (563 aa)
taf13Uncharacterized protein. (124 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (266 aa)
LOC105027634Uncharacterized protein. (611 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (702 aa)
znf385bZinc finger protein 385B. (573 aa)
nbnNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (814 aa)
LOC105024892Uncharacterized protein. (408 aa)
taf5lTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (600 aa)
csnk2a2Casein kinase 2, alpha prime polypeptide b; Belongs to the protein kinase superfamily. (350 aa)
pip4k2aPhosphatidylinositol-5-phosphate 4-kinase, type II, alpha a. (441 aa)
Pin1WW domain-containing protein. (161 aa)
mdm4MDM4 regulator of p53. (512 aa)
pip4p1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (270 aa)
LOC105023872Mitogen-activated protein kinase. (359 aa)
HIPK4Homeodomain interacting protein kinase 4. (596 aa)
LOC105021541Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (435 aa)
LOC105016722Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (394 aa)
dyrk2Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. (592 aa)
LOC105026340L3MBTL histone methyl-lysine binding protein 1a. (856 aa)
akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1108 aa)
mdm2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (484 aa)
dyrk4Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4. (627 aa)
exo1Exonuclease 1. (801 aa)
nuak2NUAK family, SNF1-like kinase, 2. (621 aa)
gatad2bGATA zinc finger domain containing 2B. (670 aa)
ing5Inhibitor of growth protein. (254 aa)
tp53rkTP53 regulating kinase. (238 aa)
LOC105026211Ubiquitin-like domain-containing protein. (128 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (468 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1033 aa)
LOC105023895Mitogen-activated protein kinase. (361 aa)
LOC105027970Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (339 aa)
LOC105023001PHD finger protein 20, b. (858 aa)
LOC105024120Ubiquitin carboxyl-terminal hydrolase. (649 aa)
LOC105007115Aurora kinase B; Belongs to the protein kinase superfamily. (334 aa)
rbbp7Retinoblastoma binding protein 4, like. (427 aa)
chd5Chromodomain helicase DNA binding protein 5. (1804 aa)
prdm1PR domain containing 1a, with ZNF domain. (826 aa)
LOC105020732Inhibitor of growth protein. (286 aa)
LOC105020742GATA zinc finger domain containing 2A. (747 aa)
tp53inp1Tumor protein p53 inducible nuclear protein 1. (272 aa)
LOC105013538Zinc finger protein 385A. (440 aa)
ehmt1Euchromatic histone-lysine N-methyltransferase 1b. (1320 aa)
LOC105020679Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (439 aa)
ENSELUP00000031146SPT16 homolog, facilitates chromatin remodeling subunit. (982 aa)
LOC105031058GATA-type domain-containing protein. (676 aa)
LOC105030639Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (265 aa)
LOC105007380Cyclin-dependent kinase 5 activator. (302 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
taf6TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (634 aa)
meaf6MYST/Esa1-associated factor 6. (220 aa)
taf1Transcription initiation factor TFIID subunit. (1979 aa)
tpx2TPX2 microtubule nucleation factor. (743 aa)
pip4k2cPhosphatidylinositol-5-phosphate 4-kinase, type II, gamma a. (415 aa)
ENSELUP00000029992TAFH domain-containing protein. (806 aa)
LOC105007983ANK_REP_REGION domain-containing protein. (1554 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa)
tbpl1TBP-like 1. (187 aa)
kat6aHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2300 aa)
LOC105023927POU domain protein. (345 aa)
LOC105028498Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (505 aa)
taf9Uncharacterized protein. (286 aa)
ehmt2Euchromatic histone-lysine N-methyltransferase 2. (1201 aa)
LOC105018845Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (392 aa)
brpf3Bromodomain and PHD finger containing, 3b. (1240 aa)
LOC105017349PHD finger protein 20, a. (1036 aa)
taf5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (752 aa)
ing1Inhibitor of growth protein. (277 aa)
LOC105015627Retinoblastoma binding protein 4. (473 aa)
LOC105014416RPTOR independent companion of MTOR, complex 2 a. (1723 aa)
pou4f1POU domain protein. (367 aa)
LOC105024716TATA box binding protein like 2. (311 aa)
LOC105026040Cyclin A2; Belongs to the cyclin family. (435 aa)
kmt5aLysine methyltransferase 5Aa. (331 aa)
TAF4BTATA-box binding protein associated factor 4b. (578 aa)
rhno1Si:ch73-352p4.5. (303 aa)
LOC105008589Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa)
setd9SET domain containing 9. (295 aa)
rad9aRAD9 checkpoint clamp component A. (352 aa)
ttc5Tetratricopeptide repeat domain 5. (444 aa)
LOC105008788PR domain containing 1b, with ZNF domain. (448 aa)
LOC105024916Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (478 aa)
tdrd3Tudor domain containing 3. (932 aa)
pou4f3POU domain protein. (338 aa)
LOC105028830Bromodomain and PHD finger containing, 3a. (1257 aa)
LOC105026079Serine/threonine-protein phosphatase. (309 aa)
rnf34Ring finger protein 34a. (389 aa)
LOC105028429Cyclin-dependent kinase 5 activator. (313 aa)
cdca7Cell division cycle associated 7a. (419 aa)
exd2Exonuclease 3'-5' domain containing 2. (660 aa)
recql4RecQ helicase-like 4. (1558 aa)
LOC105022821Zgc:86598; Belongs to the protein kinase superfamily. (392 aa)
LOC105023716Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (335 aa)
ENSELUP00000022356Uncharacterized protein. (70 aa)
LOC105031018NUAK family, SNF1-like kinase, 1a. (676 aa)
LOC105025851Chromodomain helicase DNA binding protein 4a. (1825 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
LOC105026695Serine/threonine-protein phosphatase. (309 aa)
LOC105024444Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC105014886Ring finger protein 34b. (409 aa)
LOC105025106E1A binding protein p300 a. (2761 aa)
l3mbtl3L3MBTL histone methyl-lysine binding protein 3. (806 aa)
mapkapk5MAPK activated protein kinase 5. (471 aa)
LOC105007426Mitogen-activated protein kinase. (364 aa)
ENSELUP00000020288SET and MYND domain containing 2a. (413 aa)
ENSELUP00000020281Uncharacterized protein. (117 aa)
aurkaProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (439 aa)
blmBLM RecQ like helicase. (1473 aa)
taf11TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (204 aa)
atmNon-specific serine/threonine protein kinase. (3011 aa)
mlst8WD_REPEATS_REGION domain-containing protein. (328 aa)
meiobMethionine sulfoxide reductase B1b. (471 aa)
rpa2Replication protein A2. (299 aa)
DNA2DNA replication helicase/nuclease 2. (1421 aa)
LOC105010739Ubiquitin carboxyl-terminal hydrolase. (402 aa)
ankrd11Ankyrin repeat domain 11. (2915 aa)
LOC105014960Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a. (260 aa)
LOC105021738Serine/threonine-protein phosphatase. (369 aa)
LOC105018996Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (563 aa)
LOC105012352Cyclin-dependent kinase 5 activator. (327 aa)
LOC105027313Protein kinase AMP-activated non-catalytic subunit gamma 2. (770 aa)
rfflRing finger and FYVE-like domain containing E3 ubiquitin protein ligase. (358 aa)
pip4p2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (351 aa)
TAF4TATA-box binding protein associated factor 4. (934 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (283 aa)
LOC105021685Uncharacterized protein. (765 aa)
taf12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (163 aa)
ZNF385AZinc finger protein 385A. (403 aa)
atripATR interacting protein. (863 aa)
pou4f2POU domain protein. (381 aa)
LOC105023970Zgc:171740. (349 aa)
rfc2Replication factor C (activator 1) 2. (368 aa)
ENSELUP00000014319Uncharacterized protein. (346 aa)
tbpTATA box binding protein. (302 aa)
LOC105026110SET domain-containing protein. (262 aa)
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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