STRINGSTRING
XPA XPA ppie ppie pole pole polr2g polr2g pold2 pold2 rps27a rps27a ENSELUP00000003468 ENSELUP00000003468 rfc5 rfc5 kxd1 kxd1 LOC105008829 LOC105008829 polr2d polr2d nrde2 nrde2 polr2h polr2h gtf2h2c gtf2h2c LOC105013139 LOC105013139 polr2f polr2f pcna pcna rfc4 rfc4 polr2l polr2l ercc6 ercc6 polk polk xab2 xab2 ENSELUP00000012634 ENSELUP00000012634 uvssa uvssa pold1 pold1 usp7 usp7 Polr2a Polr2a rfc2 rfc2 tceanc2 tceanc2 ENSELUP00000014716 ENSELUP00000014716 gtf2h3 gtf2h3 pole2 pole2 ENSELUP00000016997 ENSELUP00000016997 polr2i polr2i rpa2 rpa2 meiob meiob pold3 pold3 ercc4 ercc4 LOC105021082 LOC105021082 polr2e polr2e pole3 pole3 LOC105025106 LOC105025106 cul4b cul4b prpf19 prpf19 pold4 pold4 LOC105024444 LOC105024444 rpa1 rpa1 TCEANC TCEANC pole4 pole4 ENSELUP00000022977 ENSELUP00000022977 gtf2h1 gtf2h1 LOC105006037 LOC105006037 polr2b polr2b ddb1 ddb1 cul4a cul4a ercc8 ercc8 ENSELUP00000026612 ENSELUP00000026612 ercc3 ercc3 LOC105008219 LOC105008219 LOC105029954 LOC105029954 LOC105019838 LOC105019838 hmgn5 hmgn5 POLR2E POLR2E LOC105028498 LOC105028498 aqr aqr ENSELUP00000030130 ENSELUP00000030130 rbx1 rbx1 rfc3 rfc3 tcea1 tcea1 bivm bivm usp40 usp40 cdk7 cdk7 mnat1 mnat1 polr2c polr2c polr2j polr2j phf3 phf3 rpa3 rpa3 LOC105026211 LOC105026211 isy1 isy1 ercc1 ercc1 ccnh ccnh gtf2h5 gtf2h5 gtf2h4 gtf2h4 ercc2 ercc2 tcea2 tcea2 RCBTB1 RCBTB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XPAXPA, DNA damage recognition and repair factor. (272 aa)
ppiePeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (302 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1982 aa)
polr2gDNA-directed RNA polymerase II subunit RPB7. (172 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (473 aa)
rps27aRibosomal protein S27a. (177 aa)
ENSELUP00000003468Ubiquitin-like domain-containing protein. (86 aa)
rfc5AAA domain-containing protein. (335 aa)
kxd1KxDL motif containing 1. (187 aa)
LOC105008829Si:ch73-1a9.3. (83 aa)
polr2dDNA-directed RNA polymerase II subunit RPB4. (143 aa)
nrde2NRDE-2, necessary for RNA interference, domain containing. (1174 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
gtf2h2cGeneral transcription factor IIH subunit. (391 aa)
LOC105013139ATPase family AAA domain containing 5a. (1854 aa)
polr2fDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
rfc4Replication factor C (activator 1) 4. (376 aa)
polr2lDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
ercc6Excision repair cross-complementation group 6. (1494 aa)
polkPolymerase (DNA directed) kappa. (913 aa)
xab2XPA binding protein 2. (980 aa)
ENSELUP00000012634RNA_pol_L_2 domain-containing protein. (75 aa)
uvssaUV-stimulated scaffold protein A. (738 aa)
pold1DNA polymerase. (1105 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1108 aa)
Polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1892 aa)
rfc2Replication factor C (activator 1) 2. (368 aa)
tceanc2Transcription elongation factor A (SII) N-terminal and central domain containing 2. (235 aa)
ENSELUP00000014716Uncharacterized protein. (91 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (304 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
ENSELUP00000016997Uncharacterized protein. (124 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
rpa2Replication protein A2. (299 aa)
meiobMethionine sulfoxide reductase B1b. (471 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (450 aa)
ercc4Excision repair cross-complementation group 4. (892 aa)
LOC105021082Xeroderma pigmentosum, complementation group A. (272 aa)
polr2eDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (151 aa)
LOC105025106E1A binding protein p300 a. (2761 aa)
cul4bCullin 4B; Belongs to the cullin family. (858 aa)
prpf19Uncharacterized protein. (504 aa)
pold4Si:dkey-28b4.7. (109 aa)
LOC105024444Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (319 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (165 aa)
ENSELUP00000022977Chemokine (C-C motif) ligand 44. (126 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
LOC105006037Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (520 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1123 aa)
ddb1Damage-specific DNA binding protein 1. (1139 aa)
cul4aCullin 4A; Belongs to the cullin family. (760 aa)
ercc8Excision repair cross-complementation group 8. (400 aa)
ENSELUP00000026612Excision repair cross-complementation group 5. (1138 aa)
ercc3Excision repair cross-complementation group 3. (785 aa)
LOC105008219Transcription elongation factor A (SII), 3. (792 aa)
LOC105029954Pre-mRNA processing factor 19. (475 aa)
LOC105019838Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (583 aa)
hmgn5High mobility group nucleosome binding domain 6. (98 aa)
POLR2EUncharacterized protein. (210 aa)
LOC105028498Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (505 aa)
aqrAquarius intron-binding spliceosomal factor. (1498 aa)
ENSELUP00000030130Replication factor C subunit 1. (1033 aa)
rbx1Zf-rbx1 domain-containing protein. (135 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
tcea1Transcription elongation factor A (SII), 1. (292 aa)
bivmBasic, immunoglobulin-like variable motif containing. (600 aa)
usp40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1238 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (361 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (310 aa)
polr2cDNA-directed RNA polymerase II subunit RPB3. (275 aa)
polr2jDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
phf3PHD finger protein 3. (1703 aa)
rpa3Uncharacterized protein. (121 aa)
LOC105026211Ubiquitin-like domain-containing protein. (128 aa)
isy1ISY1 splicing factor homolog. (288 aa)
ercc1Excision repair cross-complementation group 1. (364 aa)
ccnhCyclin H; Belongs to the cyclin family. (323 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
tcea2Transcription elongation factor A (SII), 2. (306 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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