7 items (Esox lucius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sh2d5	SH2 domain containing 5. (406 aa)
	appl1	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (711 aa)
	ENSELUP00000030553	PID domain-containing protein. (300 aa)
	fam43a	Family with sequence similarity 43 member A. (346 aa)
	appl2	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (665 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (609 aa)
	pid1	Phosphotyrosine interaction domain containing 1. (224 aa)

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSELUP00000030553	appl1	ENSELUP00000030553	ENSELUP00000020945	PID domain-containing protein.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	0.639
ENSELUP00000030553	appl2	ENSELUP00000030553	ENSELUP00000031547	PID domain-containing protein.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	0.639
appl1	ENSELUP00000030553	ENSELUP00000020945	ENSELUP00000030553	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	PID domain-containing protein.	0.639
appl1	appl2	ENSELUP00000020945	ENSELUP00000031547	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	0.989
appl2	ENSELUP00000030553	ENSELUP00000031547	ENSELUP00000030553	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	PID domain-containing protein.	0.639
appl2	appl1	ENSELUP00000031547	ENSELUP00000020945	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	0.989