STRINGSTRING
LOC105013349 LOC105013349 ENSELUP00000036695 ENSELUP00000036695 calm2 calm2 LOC105017162 LOC105017162 STAT1 STAT1 LOC105028068 LOC105028068 LOC105022623 LOC105022623 plek plek SNCA SNCA LOC105015223 LOC105015223 LOC105018659 LOC105018659 plcg1 plcg1 LOC105013934 LOC105013934 LOC105028434 LOC105028434 ccnd1 ccnd1 LOC105031019 LOC105031019 egf egf cdk4 cdk4 LOC105031491 LOC105031491 stat3 stat3 LOC105005877 LOC105005877 LOC105007255 LOC105007255 LOC105022527 LOC105022527 stat4 stat4 mdm2 mdm2 cdk5 cdk5 ENSELUP00000041804 ENSELUP00000041804 ENSELUP00000012846 ENSELUP00000012846 LOC105028684 LOC105028684 LOC105023834 LOC105023834 LOC105027628 LOC105027628 casp3 casp3 LOC105018279 LOC105018279 bdnf bdnf LOC105013164 LOC105013164 LOC105030962 LOC105030962 LOC105017693 LOC105017693 LOC105015185 LOC105015185 ntn1 ntn1 calm1 calm1 casp3-2 casp3-2 plek2 plek2 pten pten ENSELUP00000040464 ENSELUP00000040464 cdk2 cdk2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105013349Signal transducer and activator of transcription. (799 aa)
ENSELUP00000036695Unc-5 netrin receptor B. (864 aa)
calm2Calmodulin 2. (149 aa)
LOC105017162Signal transducer and activator of transcription. (804 aa)
STAT1Signal transducer and activator of transcription. (988 aa)
LOC105028068Calmodulin. (149 aa)
LOC105022623Tyrosine-protein kinase receptor. (1378 aa)
plekPleckstrin. (352 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (159 aa)
LOC105015223Nucleophosmin/nucleoplasmin, 2b. (193 aa)
LOC105018659Calmodulin-like 4b. (153 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1315 aa)
LOC105013934Calmodulin-like 4a. (153 aa)
LOC105028434Prolactin. (210 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
LOC105031019Prolactin 2. (232 aa)
egfEpidermal growth factor. (1230 aa)
cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
LOC105031491Netrin 5. (858 aa)
stat3Signal transducer and activator of transcription. (859 aa)
LOC105005877Tyrosine-protein kinase receptor. (1373 aa)
LOC105007255Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily. (280 aa)
LOC105022527Signal transducer and activator of transcription. (774 aa)
stat4Signal transducer and activator of transcription. (741 aa)
mdm2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (484 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ENSELUP00000041804Uncharacterized protein; Belongs to the actin family. (415 aa)
ENSELUP00000012846Glutamate receptor interacting protein 1. (1044 aa)
LOC105028684IF rod domain-containing protein. (845 aa)
LOC105023834Signal transducer and activator of transcription. (758 aa)
LOC105027628Signal transducer and activator of transcription. (785 aa)
casp3Uncharacterized protein; Belongs to the peptidase C14A family. (278 aa)
LOC105018279Cyclin D1; Belongs to the cyclin family. (502 aa)
bdnfBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (271 aa)
LOC105013164Netrin 1b. (600 aa)
LOC105030962Netrin 2. (638 aa)
LOC105017693Calmodulin 3a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
LOC105015185Uncharacterized protein; Belongs to the peptidase C14A family. (289 aa)
ntn1Netrin 1a. (603 aa)
calm1Uncharacterized protein; Belongs to the calmodulin family. (216 aa)
casp3-2Uncharacterized protein; Belongs to the peptidase C14A family. (332 aa)
plek2Pleckstrin 2. (360 aa)
ptenPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (366 aa)
ENSELUP00000040464Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (62 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (301 aa)
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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