36 items (Esox lucius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105027310	Receptor protein-tyrosine kinase. (1184 aa)
	ENSELUP00000036695	Unc-5 netrin receptor B. (864 aa)
	calm2	Calmodulin 2. (149 aa)
	LOC105028068	Calmodulin. (149 aa)
	LOC105022623	Tyrosine-protein kinase receptor. (1378 aa)
	plek	Pleckstrin. (352 aa)
	nf2	Neurofibromin 2a (merlin). (591 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	LOC105018659	Calmodulin-like 4b. (153 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1315 aa)
	LOC105019998	Receptor protein-tyrosine kinase. (1229 aa)
	ENSELUP00000023922	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (851 aa)
	LOC105013934	Calmodulin-like 4a. (153 aa)
	LOC105028434	Prolactin. (210 aa)
	rabif	RAB interacting factor. (133 aa)
	LOC105031019	Prolactin 2. (232 aa)
	egf	Epidermal growth factor. (1230 aa)
	cdk4	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
	LOC105031491	Netrin 5. (858 aa)
	LOC105005877	Tyrosine-protein kinase receptor. (1373 aa)
	LOC105007255	Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily. (280 aa)
	ENSELUP00000013506	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (830 aa)
	mdm2	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (484 aa)
	Vav1	Calponin-homology (CH) domain-containing protein. (92 aa)
	LOC105013164	Netrin 1b. (600 aa)
	LOC105030962	Netrin 2. (638 aa)
	LOC105017693	Calmodulin 3a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
	jak2	Tyrosine-protein kinase. (1124 aa)
	ntn1	Netrin 1a. (603 aa)
	calm1	Uncharacterized protein; Belongs to the calmodulin family. (216 aa)
	LOC105030880	Neurofibromin 2b (merlin). (616 aa)
	iqgap1	IQ motif containing GTPase activating protein 1. (1656 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	plek2	Pleckstrin 2. (360 aa)
	ENSELUP00000040464	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (62 aa)
	cdk2	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (301 aa)

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSELUP00000013506	ENSELUP00000023922	ENSELUP00000013506	ENSELUP00000023922	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.900
ENSELUP00000013506	Vav1	ENSELUP00000013506	ENSELUP00000010912	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Calponin-homology (CH) domain-containing protein.	0.551
ENSELUP00000023922	ENSELUP00000013506	ENSELUP00000023922	ENSELUP00000013506	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.900
ENSELUP00000023922	Vav1	ENSELUP00000023922	ENSELUP00000010912	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Calponin-homology (CH) domain-containing protein.	0.551
ENSELUP00000036695	LOC105013164	ENSELUP00000036695	ENSELUP00000008989	Unc-5 netrin receptor B.	Netrin 1b.	0.774
ENSELUP00000036695	LOC105030962	ENSELUP00000036695	ENSELUP00000008096	Unc-5 netrin receptor B.	Netrin 2.	0.849
ENSELUP00000036695	LOC105031491	ENSELUP00000036695	ENSELUP00000019904	Unc-5 netrin receptor B.	Netrin 5.	0.767
ENSELUP00000036695	ntn1	ENSELUP00000036695	ENSELUP00000005000	Unc-5 netrin receptor B.	Netrin 1a.	0.774
ENSELUP00000040464	LOC105005877	ENSELUP00000040464	ENSELUP00000019214	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.800
ENSELUP00000040464	LOC105022623	ENSELUP00000040464	ENSELUP00000034920	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.800
ENSELUP00000040464	egf	ENSELUP00000040464	ENSELUP00000021996	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Epidermal growth factor.	0.739
LOC105005877	ENSELUP00000040464	ENSELUP00000019214	ENSELUP00000040464	Tyrosine-protein kinase receptor.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.800
LOC105005877	egf	ENSELUP00000019214	ENSELUP00000021996	Tyrosine-protein kinase receptor.	Epidermal growth factor.	0.461
LOC105005877	mdm2	ENSELUP00000019214	ENSELUP00000013477	Tyrosine-protein kinase receptor.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.488
LOC105007255	cdk4	ENSELUP00000016577	ENSELUP00000021506	Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily.	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	0.903
LOC105013164	ENSELUP00000036695	ENSELUP00000008989	ENSELUP00000036695	Netrin 1b.	Unc-5 netrin receptor B.	0.774
LOC105013164	mdm2	ENSELUP00000008989	ENSELUP00000013477	Netrin 1b.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.528
LOC105013934	LOC105017693	ENSELUP00000023723	ENSELUP00000006756	Calmodulin-like 4a.	Calmodulin 3a (phosphorylase kinase, delta); Belongs to the calmodulin family.	0.917
LOC105013934	LOC105018659	ENSELUP00000023723	ENSELUP00000026793	Calmodulin-like 4a.	Calmodulin-like 4b.	0.901
LOC105013934	cdk5	ENSELUP00000023723	ENSELUP00000041388	Calmodulin-like 4a.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.413