STRINGSTRING
LOC105015086 LOC105015086 TGFB3 TGFB3 LOC105026733 LOC105026733 LOC105028100 LOC105028100 AMHR2 AMHR2 bmp2 bmp2 nodal nodal LOC105027013 LOC105027013 LOC105010856 LOC105010856 bmp5 bmp5 LOC105027026 LOC105027026 gdf10 gdf10 tgfb3 tgfb3 bmp4 bmp4 tgfb2 tgfb2 LOC105016079 LOC105016079 bmp3 bmp3 amh amh ENSELUP00000040464 ENSELUP00000040464 inha inha ENSELUP00000041804 ENSELUP00000041804
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105015086Nodal-related 1. (411 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa)
LOC105026733Transforming growth factor beta; Belongs to the TGF-beta family. (434 aa)
LOC105028100Left-right determination factor. (363 aa)
AMHR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (494 aa)
bmp2Bone morphogenetic protein 2b. (419 aa)
nodalNodal-related 2. (401 aa)
LOC105027013Southpaw. (423 aa)
LOC105010856Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
bmp5Bone morphogenetic protein 5. (457 aa)
LOC105027026Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
gdf10Growth differentiation factor 10b. (445 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
bmp4Bone morphogenetic protein 4. (443 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
LOC105016079Left-right determination factor. (359 aa)
bmp3Bone morphogenetic protein 3. (490 aa)
amhAnti-Mullerian hormone. (574 aa)
ENSELUP00000040464Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (62 aa)
inhaInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (354 aa)
ENSELUP00000041804Uncharacterized protein; Belongs to the actin family. (415 aa)
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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