STRINGSTRING
LOC105013139 LOC105013139 ENSELUP00000007842 ENSELUP00000007842 rad51b rad51b rfc4 rfc4 DNAH8 DNAH8 LOC105006976 LOC105006976 ENSELUP00000009028 ENSELUP00000009028 LOC105028204 LOC105028204 LOC105030416 LOC105030416 cdc6 cdc6 ENSELUP00000000769 ENSELUP00000000769 abcd3 abcd3 LOC105006106 LOC105006106 clpx clpx abca2 abca2 atad1 atad1 ABCC4 ABCC4 LOC105012221 LOC105012221 rad51 rad51 rfc5 rfc5 abcb7 abcb7 ENSELUP00000004023 ENSELUP00000004023 abcb9 abcb9 ENSELUP00000004691 ENSELUP00000004691 abcc5 abcc5 LOC105018828 LOC105018828 LOC105019379 LOC105019379 LOC105008983 LOC105008983 ENSELUP00000006644 ENSELUP00000006644 LOC105014378 LOC105014378 ENSELUP00000007350 ENSELUP00000007350 yme1l1 yme1l1 ruvbl2 ruvbl2 ENSELUP00000007481 ENSELUP00000007481 mcm7 mcm7 Dnah2 Dnah2 ENSELUP00000042374 ENSELUP00000042374 ENSELUP00000042106 ENSELUP00000042106 psmc2 psmc2 atp5f1b atp5f1b SPATA5 SPATA5 nav3 nav3 mcm4 mcm4 abcc9 abcc9 LOC105027254 LOC105027254 ENSELUP00000039735 ENSELUP00000039735 ENSELUP00000039554 ENSELUP00000039554 dmc1 dmc1 cnp cnp abcc12 abcc12 VPS4B VPS4B abcc8 abcc8 LOC105024981 LOC105024981 ENSELUP00000037651 ENSELUP00000037651 LOC105018078 LOC105018078 ruvbl1 ruvbl1 psmc4 psmc4 tor2a tor2a lonp2 lonp2 LOC105030869 LOC105030869 ATAD3A ATAD3A dnah10 dnah10 LOC105016180 LOC105016180 katnal2 katnal2 abcg5 abcg5 abcg8 abcg8 abcc2 abcc2 LOC105025565 LOC105025565 lonp1 lonp1 LOC105015905 LOC105015905 abcc10 abcc10 mcm5 mcm5 dhx37 dhx37 mcm3 mcm3 LOC105017573 LOC105017573 abcg4 abcg4 rfc3 rfc3 LOC105017692 LOC105017692 psmc6 psmc6 ENSELUP00000030130 ENSELUP00000030130 KATNAL1 KATNAL1 abcf3 abcf3 LOC105031138 LOC105031138 dnah5 dnah5 gpn1 gpn1 PSMC1 PSMC1 spata5l1 spata5l1 LOC105026399 LOC105026399 dnah12 dnah12 psmc5 psmc5 trip13 trip13 nav2 nav2 abcf1 abcf1 ascc3 ascc3 LOC105007532 LOC105007532 LOC105019988 LOC105019988 zhx1 zhx1 ENSELUP00000023603 ENSELUP00000023603 LOC105028430 LOC105028430 LOC105019658 LOC105019658 LOC105020003 LOC105020003 ENSELUP00000023273 ENSELUP00000023273 dnah9 dnah9 psmc3 psmc3 tor4a tor4a pex1 pex1 orc1 orc1 mcm9 mcm9 abcc3 abcc3 ENSELUP00000021535 ENSELUP00000021535 ENSELUP00000021160 ENSELUP00000021160 LOC105009449 LOC105009449 LOC105019328 LOC105019328 wrnip1 wrnip1 ENSELUP00000020294 ENSELUP00000020294 pif1 pif1 LOC105021086 LOC105021086 abcd1 abcd1 ntpcr ntpcr DHX15 DHX15 snrnp200 snrnp200 katna1 katna1 LOC105028047 LOC105028047 spg7 spg7 LOC105020625 LOC105020625 SPAST SPAST LOC105025015 LOC105025015 pex6 pex6 afg3l2 afg3l2 LOC105022110 LOC105022110 LOC105026795 LOC105026795 ENSELUP00000017019 ENSELUP00000017019 LOC105025812 LOC105025812 LOC105024984 LOC105024984 LOC105031438 LOC105031438 dync1h1 dync1h1 LOC105005973 LOC105005973 abcg2 abcg2 LOC105011778 LOC105011778 orc4 orc4 abcb10 abcb10 ENSELUP00000014517 ENSELUP00000014517 RNF213 RNF213 abce1 abce1 rfc2 rfc2 NUBP1 NUBP1 atad2b atad2b ENSELUP00000013573 ENSELUP00000013573 ENSELUP00000013502 ENSELUP00000013502 mcm8 mcm8 Helz2 Helz2 nvl nvl LOC105021865 LOC105021865 vps4a vps4a ENSELUP00000012434 ENSELUP00000012434 ENSELUP00000010463 ENSELUP00000010463 ENSELUP00000010328 ENSELUP00000010328 LOC105023836 LOC105023836 ENSELUP00000010080 ENSELUP00000010080 ENSELUP00000009811 ENSELUP00000009811 ENSELUP00000009801 ENSELUP00000009801
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105013139ATPase family AAA domain containing 5a. (1854 aa)
ENSELUP00000007842ATP-binding cassette, sub-family D (ALD), member 4. (560 aa)
rad51bRAD51 paralog B. (378 aa)
rfc4Replication factor C (activator 1) 4. (376 aa)
DNAH8Dynein axonemal heavy chain 8. (4403 aa)
LOC105006976Transporter associated with antigen processing, subunit type t, teleost specific. (711 aa)
ENSELUP00000009028AAA domain-containing protein. (493 aa)
LOC105028204ATP-binding cassette, sub-family D (ALD), member 2. (746 aa)
LOC105030416Uncharacterized protein. (1708 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (568 aa)
ENSELUP00000000769ATP-binding cassette, sub-family A (ABC1), member 4a. (2213 aa)
abcd3ATP-binding cassette, sub-family D (ALD), member 3a. (660 aa)
LOC105006106Uncharacterized protein; Belongs to the AAA ATPase family. (806 aa)
clpxCaseinolytic mitochondrial matrix peptidase chaperone subunit a. (602 aa)
abca2ATP-binding cassette, sub-family A (ABC1), member 2. (2381 aa)
atad1ATPase family AAA domain containing 1b; Belongs to the AAA ATPase family. (441 aa)
ABCC4ATP binding cassette subfamily C member 4. (1326 aa)
LOC105012221ATP-binding cassette, sub-family C (CFTR/MRP), member 6a. (1513 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)
rfc5AAA domain-containing protein. (335 aa)
abcb7ATP-binding cassette, sub-family B (MDR/TAP), member 7. (743 aa)
ENSELUP00000004023Uncharacterized protein. (826 aa)
abcb9ATP-binding cassette, sub-family B (MDR/TAP), member 9. (815 aa)
ENSELUP00000004691ATP-binding cassette, sub-family A (ABC1), member 4b. (2254 aa)
abcc5ATP-binding cassette, sub-family C (CFTR/MRP), member 5. (1152 aa)
LOC105018828ATP-binding cassette, sub-family B (MDR/TAP), member 5. (1321 aa)
LOC105019379Uncharacterized protein. (666 aa)
LOC105008983ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1. (1507 aa)
ENSELUP00000006644ABC transporter domain-containing protein. (644 aa)
LOC105014378ATPase family AAA domain containing 1a; Belongs to the AAA ATPase family. (381 aa)
ENSELUP00000007350N-ethylmaleimide-sensitive factor b; Belongs to the AAA ATPase family. (674 aa)
yme1l1YME1-like 1a. (721 aa)
ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
ENSELUP00000007481ATP-binding cassette, sub-family A (ABC1), member 12. (1999 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (730 aa)
Dnah2Dynein, axonemal, heavy chain 2. (4376 aa)
ENSELUP00000042374Transporter associated with antigen processing, subunit type a. (724 aa)
ENSELUP00000042106Immunoglobulin mu DNA binding protein 2. (965 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (434 aa)
atp5f1bATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (517 aa)
SPATA5Spermatogenesis associated 5. (935 aa)
nav3Neuron navigator 3. (2389 aa)
mcm4DNA helicase; Belongs to the MCM family. (858 aa)
abcc9ATP-binding cassette, sub-family C (CFTR/MRP), member 9. (1535 aa)
LOC105027254Neuron navigator 1b. (1540 aa)
ENSELUP00000039735ATP-binding cassette, sub-family B (MDR/TAP), member 6a. (435 aa)
ENSELUP00000039554Fidgetin; Belongs to the AAA ATPase family. (715 aa)
dmc1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (342 aa)
cnp2',3'-cyclic nucleotide 3' phosphodiesterase. (723 aa)
abcc12ATP-binding cassette, sub-family C (CFTR/MRP), member 12. (1366 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (437 aa)
abcc8ATP-binding cassette, sub-family C (CFTR/MRP), member 8. (1596 aa)
LOC105024981ATP-binding cassette, sub-family F (GCN20), member 2a. (611 aa)
ENSELUP00000037651Uncharacterized protein. (2821 aa)
LOC105018078Neuron navigator 2b. (2176 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
tor2aTorsin. (318 aa)
lonp2Lon protease homolog; Belongs to the peptidase S16 family. (897 aa)
LOC105030869Guanylate kinase 1b. (437 aa)
ATAD3AATPase family AAA domain containing 3A. (702 aa)
dnah10Dynein axonemal heavy chain 10. (4445 aa)
LOC105016180BC1 (ubiquinol-cytochrome c reductase) synthesis-like; Belongs to the AAA ATPase family. (420 aa)
katnal2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (536 aa)
abcg5ATP-binding cassette, sub-family G (WHITE), member 5. (671 aa)
abcg8ATP-binding cassette, sub-family G (WHITE), member 8. (661 aa)
abcc2Uncharacterized protein. (1584 aa)
LOC105025565Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
lonp1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1013 aa)
LOC105015905AAA domain-containing protein. (785 aa)
abcc10ATP-binding cassette, sub-family C (CFTR/MRP), member 10. (1556 aa)
mcm5DNA helicase; Belongs to the MCM family. (739 aa)
dhx37DEAH (Asp-Glu-Ala-His) box polypeptide 37. (1149 aa)
mcm3DNA helicase; Belongs to the MCM family. (812 aa)
LOC105017573Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
abcg4ATP-binding cassette, sub-family G (WHITE), member 4a. (683 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
LOC105017692Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
psmc6AAA domain-containing protein; Belongs to the AAA ATPase family. (389 aa)
ENSELUP00000030130Replication factor C subunit 1. (1033 aa)
KATNAL1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (492 aa)
abcf3ATP-binding cassette, sub-family F (GCN20), member 3. (722 aa)
LOC105031138Si:ch1073-174d20.2. (768 aa)
dnah5Dynein, axonemal, heavy chain 5. (4599 aa)
gpn1GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (398 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
spata5l1Spermatogenesis associated 5-like 1. (777 aa)
LOC105026399DNA helicase; Belongs to the MCM family. (813 aa)
dnah12Dynein, axonemal, heavy chain 12. (2982 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (423 aa)
trip13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (426 aa)
nav2Neuron navigator 2a. (2481 aa)
abcf1ATP-binding cassette, sub-family F (GCN20), member 1. (863 aa)
ascc3Activating signal cointegrator 1 complex subunit 3. (2212 aa)
LOC105007532ATP binding cassette subfamily A member 1. (2371 aa)
LOC105019988ATP-binding cassette, sub-family C (CFTR/MRP), member 4. (1321 aa)
zhx1ATPase family AAA domain containing 2. (898 aa)
ENSELUP00000023603ATP-binding cassette, sub-family B (MDR/TAP), member 11b. (1239 aa)
LOC105028430N-ethylmaleimide-sensitive factor a. (760 aa)
LOC105019658ATP-binding cassette, sub-family B (MDR/TAP), member 8. (709 aa)
LOC105020003AAA domain-containing protein. (757 aa)
ENSELUP00000023273Uncharacterized protein. (867 aa)
dnah9Uncharacterized protein. (4464 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (437 aa)
tor4aTorsin family 4, member Ab. (400 aa)
pex1Peroxisomal biogenesis factor 1. (1291 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (940 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1418 aa)
abcc3ATP-binding cassette, sub-family C (CFTR/MRP), member 3. (1555 aa)
ENSELUP00000021535Caseinolytic mitochondrial matrix peptidase chaperone subunit b. (593 aa)
ENSELUP00000021160ATP-binding cassette, sub-family B (MDR/TAP), member 11a. (1215 aa)
LOC105009449ATP-binding cassette, sub-family B (MDR/TAP), member 6a. (397 aa)
LOC105019328Uncharacterized protein. (4206 aa)
wrnip1WRN helicase interacting protein 1. (615 aa)
ENSELUP00000020294Transporter associated with antigen processing, subunit type a. (715 aa)
pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (682 aa)
LOC105021086ATP-binding cassette, sub-family A (ABC1), member 1A. (2286 aa)
abcd1ATP-binding cassette, sub-family D (ALD), member 1. (783 aa)
ntpcrNucleoside-triphosphatase, cancer-related. (193 aa)
DHX15DEAH-box helicase 15. (747 aa)
snrnp200Small nuclear ribonucleoprotein 200 (U5). (2137 aa)
katna1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (488 aa)
LOC105028047Bromo domain-containing protein. (1135 aa)
spg7SPG7 matrix AAA peptidase subunit, paraplegin. (811 aa)
LOC105020625Uncharacterized protein. (2248 aa)
SPASTSpastin; Belongs to the AAA ATPase family. (521 aa)
LOC105025015RING-type domain-containing protein. (4422 aa)
pex6Peroxisomal biogenesis factor 6. (1086 aa)
afg3l2AFG3-like AAA ATPase 2. (806 aa)
LOC105022110DEAH (Asp-Glu-Ala-His) box helicase 15. (758 aa)
LOC105026795ATP-binding cassette, sub-family G (WHITE), member 1. (671 aa)
ENSELUP00000017019CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (806 aa)
LOC105025812Si:ch211-221f10.2. (1422 aa)
LOC105024984YME1-like 1b. (718 aa)
LOC105031438Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (590 aa)
dync1h1Dynein, cytoplasmic 1, heavy chain 1. (4627 aa)
LOC105005973AAA domain-containing protein. (1968 aa)
abcg2ATP-binding cassette, sub-family G (WHITE), member 2d. (661 aa)
LOC105011778ATP-binding cassette, sub-family G (WHITE), member 4b. (655 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (464 aa)
abcb10ATP-binding cassette, sub-family B (MDR/TAP), member 10. (718 aa)
ENSELUP00000014517Zgc:136908; Belongs to the AAA ATPase family. (766 aa)
RNF213Ring finger protein 213. (4234 aa)
abce1ATP-binding cassette, sub-family E (OABP), member 1. (599 aa)
rfc2Replication factor C (activator 1) 2. (368 aa)
NUBP1Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (303 aa)
atad2bATPase family AAA domain containing 2B. (1476 aa)
ENSELUP00000013573ATP-binding cassette, sub-family H, member 1. (705 aa)
ENSELUP00000013502ATP-binding cassette, sub-family H, member 1. (640 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (820 aa)
Helz2Helicase with zinc finger 2, transcriptional coactivator. (2805 aa)
nvlNuclear VCP like. (888 aa)
LOC105021865Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). (752 aa)
vps4aVacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (436 aa)
ENSELUP00000012434Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
ENSELUP00000010463Zgc:172302. (2333 aa)
ENSELUP00000010328ATP-binding cassette, sub-family G (WHITE), member 2c. (541 aa)
LOC105023836AAA domain-containing protein. (751 aa)
ENSELUP00000010080Ring finger protein 213b. (3253 aa)
ENSELUP00000009811ATP-binding cassette, sub-family C (CFTR/MRP), member 1. (1435 aa)
ENSELUP00000009801ATP-binding cassette, sub-family B (MDR/TAP), member 4. (976 aa)
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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