STRINGSTRING
myd88 myd88 map3k8 map3k8 LOC105026239 LOC105026239 LOC105020225 LOC105020225 LOC105020226 LOC105020226 traf3 traf3 akt1 akt1 AKT1 AKT1 LOC105005941 LOC105005941 LOC105013860 LOC105013860 LOC105013652 LOC105013652 RAC1 RAC1 LOC105012296 LOC105012296 nfkbia nfkbia LOC105009489 LOC105009489 LOC105018625 LOC105018625 LOC106024123 LOC106024123 LOC105012269 LOC105012269 LOC105025378 LOC105025378 tlr2 tlr2 LOC105010696 LOC105010696 irak4 irak4 ikbkb ikbkb CHUK CHUK LOC105010684 LOC105010684 LOC105013993 LOC105013993 LOC105027407 LOC105027407 ccl22 ccl22 irf5 irf5 LOC105023872 LOC105023872 LOC105015312 LOC105015312 LOC105023401 LOC105023401 akt3 akt3 LOC105031287 LOC105031287 LOC105026332 LOC105026332 LOC105020694 LOC105020694 LOC105020506 LOC105020506 LOC105031508 LOC105031508 LOC105031509 LOC105031509 LOC105031504 LOC105031504 MAPK9 MAPK9 LOC105022527 LOC105022527 LOC105018780 LOC105018780 LOC106024448 LOC106024448 tirap tirap RAC1-2 RAC1-2 irak1 irak1 ikbkg ikbkg LOC109614581 LOC109614581 tab1 tab1 Mapk10 Mapk10 LOC105014544 LOC105014544 LOC109616205 LOC109616205 LOC105007339 LOC105007339 LOC105024916 LOC105024916 LOC105024911 LOC105024911 Jun Jun LOC105012469 LOC105012469 LOC105021974 LOC105021974 LOC105009140 LOC105009140 irf7 irf7 LOC105005940 LOC105005940 ENSELUP00000028602 ENSELUP00000028602 LOC105021259 LOC105021259 LOC105021271 LOC105021271 LOC105006595 LOC105006595 LOC105006256 LOC105006256 pik3r1 pik3r1 LOC105020581 LOC105020581 tollip tollip LOC105027233 LOC105027233 ctsk ctsk map2k7 map2k7 ENSELUP00000033261 ENSELUP00000033261 LOC105006190 LOC105006190 LOC105005611 LOC105005611 LOC105023895 LOC105023895 Mapk1 Mapk1 LOC105009870 LOC105009870 TLR5 TLR5 akt2 akt2 ENSELUP00000034693 ENSELUP00000034693 ENSELUP00000034723 ENSELUP00000034723 LOC105031348 LOC105031348 TLR8 TLR8 LOC105026796 LOC105026796 LOC105011557 LOC105011557 MAP2K4 MAP2K4 tab2 tab2 LOC105026167 LOC105026167 ripk1 ripk1 traf6 traf6 tlr3 tlr3 LOC105023011 LOC105023011 il12b il12b LOC105014542 LOC105014542 LOC105024762 LOC105024762 LOC105012809 LOC105012809 LOC105017402 LOC105017402 PIK3CA PIK3CA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (287 aa)
map3k8Mitogen-activated protein kinase kinase kinase 8. (473 aa)
LOC105026239Interferon regulatory factor 3. (448 aa)
LOC105020225Mitogen-activated protein kinase. (364 aa)
LOC105020226Mitogen-activated protein kinase. (361 aa)
traf3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (576 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (474 aa)
LOC105005941V-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (375 aa)
LOC105013860Mitogen-activated protein kinase. (364 aa)
LOC105013652Tumor necrosis factor receptor superfamily member 5. (322 aa)
RAC1Rac family small GTPase 1. (192 aa)
LOC105012296Uncharacterized protein. (111 aa)
nfkbiaANK_REP_REGION domain-containing protein. (322 aa)
LOC105009489Interleukin-1. (252 aa)
LOC105018625Uncharacterized protein. (655 aa)
LOC106024123Interferon phi 4. (186 aa)
LOC105012269Uncharacterized protein. (293 aa)
LOC105025378Uncharacterized protein. (721 aa)
tlr2Toll-like receptor 2. (855 aa)
LOC105010696Component of inhibitor of nuclear factor kappa B kinase complex. (791 aa)
irak4Interleukin-1 receptor-associated kinase 4. (464 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (765 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (759 aa)
LOC105010684SCY domain-containing protein. (212 aa)
LOC105013993Toll-like receptor 9; Belongs to the Toll-like receptor family. (1082 aa)
LOC105027407Mitogen-activated protein kinase kinase 6. (290 aa)
ccl22C-C motif chemokine 4. (104 aa)
irf5Interferon regulatory factor 5. (492 aa)
LOC105023872Mitogen-activated protein kinase. (359 aa)
LOC105015312Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (314 aa)
LOC105023401Uncharacterized protein. (193 aa)
akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC105031287Protein kinase domain-containing protein. (336 aa)
LOC105026332BPI fold containing family C, like. (476 aa)
LOC105020694V-rel avian reticuloendotheliosis viral oncogene homolog A. (621 aa)
LOC105020506JunE proto-oncogene, AP-1 transcription factor subunit. (356 aa)
LOC105031508Ig-like domain-containing protein. (260 aa)
LOC105031509Ig-like domain-containing protein. (281 aa)
LOC105031504Uncharacterized protein. (488 aa)
MAPK9Mitogen-activated protein kinase. (418 aa)
LOC105022527Signal transducer and activator of transcription. (774 aa)
LOC105018780Toll-like receptor 7; Belongs to the Toll-like receptor family. (1059 aa)
LOC106024448Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (98 aa)
tirapToll-interleukin 1 receptor (TIR) domain containing adaptor protein. (198 aa)
RAC1-2Rac family small GTPase 1. (192 aa)
irak1Interleukin-1 receptor-associated kinase 1. (721 aa)
ikbkgInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (601 aa)
LOC109614581Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (729 aa)
tab1TGF-beta activated kinase 1/MAP3K7 binding protein 1. (523 aa)
Mapk10Mitogen-activated protein kinase. (259 aa)
LOC105014544SCY domain-containing protein. (93 aa)
LOC109616205Interleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (200 aa)
LOC105007339Interleukin-1. (282 aa)
LOC105024916Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (478 aa)
LOC105024911Mitogen-activated protein kinase. (421 aa)
JunBZIP domain-containing protein. (314 aa)
LOC105012469Uncharacterized protein. (222 aa)
LOC105021974Uncharacterized protein. (480 aa)
LOC105009140IL12p40_C domain-containing protein. (328 aa)
irf7Interferon regulatory factor 7. (448 aa)
LOC105005940Si:ch211-153j24.3. (439 aa)
ENSELUP00000028602TIR domain-containing protein; Belongs to the Toll-like receptor family. (1030 aa)
LOC105021259Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (485 aa)
LOC105021271Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (417 aa)
LOC105006595Mitogen-activated protein kinase. (384 aa)
LOC105006256Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (355 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
LOC105020581Mitogen-activated protein kinase kinase 2b; Belongs to the protein kinase superfamily. (399 aa)
tollipToll-interacting protein; Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity). (295 aa)
LOC105027233Mitogen-activated protein kinase. (469 aa)
ctskCathepsin K; Belongs to the peptidase C1 family. (331 aa)
map2k7Mitogen-activated protein kinase kinase 7. (439 aa)
ENSELUP00000033261Toll-like receptor 18. (890 aa)
LOC105006190Uncharacterized protein; Belongs to the peptidase C14A family. (450 aa)
LOC105005611TIR domain-containing protein; Belongs to the Toll-like receptor family. (777 aa)
LOC105023895Mitogen-activated protein kinase. (361 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (371 aa)
LOC105009870Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (396 aa)
TLR5Toll like receptor 5; Belongs to the Toll-like receptor family. (907 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (468 aa)
ENSELUP00000034693Uncharacterized protein. (176 aa)
ENSELUP00000034723Interferon phi 1. (177 aa)
LOC105031348Tumor necrosis factor b (TNF superfamily, member 2). (254 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1030 aa)
LOC105026796Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (96 aa)
LOC105011557Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (401 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (434 aa)
tab2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (733 aa)
LOC105026167Toll-like receptor 1. (862 aa)
ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (723 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
tlr3Toll-like receptor 3; Belongs to the Toll-like receptor family. (911 aa)
LOC105023011Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (426 aa)
il12bInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (317 aa)
LOC105014542Chemokine (C-X-C motif) ligand 11, duplicate 1. (99 aa)
LOC105024762Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (564 aa)
LOC105012809Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
LOC105017402Inhibitor of nuclear factor kappa B kinase subunit epsilon. (725 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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