(29 nodes) Mixed, incl. Activation of caspases through apoptosome-mediated cleavage, and Peptidase C14, p20 domain network (Salmo salar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106600607	Baculoviral IAP repeat-containing protein 7-like isoform X2. (454 aa)
	LOC106604062	Inhibitor of apoptosis protein-like isoform X1. (650 aa)
	CASP2	Caspase-2-like; Belongs to the peptidase C14A family. (343 aa)
	LOC106572692	Baculoviral IAP repeat-containing protein 5.1-A-like isoform X2. (146 aa)
	LOC106576445	Apoptotic protease-activating factor 1-like isoform X1. (1274 aa)
	LOC106590758	Caspase-14-like; Belongs to the peptidase C14A family. (187 aa)
	LOC106590759	Caspase-14-like; Belongs to the peptidase C14A family. (254 aa)
	LOC106602722	Caspase-3-like; Belongs to the peptidase C14A family. (284 aa)
	LOC106603345	Diablo homolog, mitochondrial-like. (233 aa)
	LOC106612162	Baculoviral IAP repeat-containing protein 4. (467 aa)
	LOC106566594	Baculoviral IAP repeat-containing protein 7-like isoform X2. (526 aa)
	LOC106609292	Death domain-containing protein CRADD-like. (200 aa)
	LOC106569483	Caspase-8-like; Belongs to the peptidase C14A family. (159 aa)
	LOC106609566	Apoptotic protease-activating factor 1-like isoform X1. (1358 aa)
	sptan1	Spectrin alpha chain, non-erythrocytic 1 isoform X1. (2487 aa)
	sptan1-2	Spectrin alpha chain, non-erythrocytic 1-like isoform X1. (2530 aa)
	LOC106584781	P53-induced death domain-containing protein 1-like. (493 aa)
	LOC106586251	Cytochrome C; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
	LOC106582467	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	LOC106612018	Caspase-3-like; Belongs to the peptidase C14A family. (283 aa)
	LOC106581203	Diablo homolog, mitochondrial-like. (265 aa)
	LOC106576178	Death domain-containing protein CRADD-like. (224 aa)
	casp9	Caspase-9 isoform X1; Belongs to the peptidase C14A family. (450 aa)
	LOC106567147	Caspase-9-like; Belongs to the peptidase C14A family. (456 aa)
	LOC106576719	Caspase-2-like isoform X1; Belongs to the peptidase C14A family. (485 aa)
	LOC106563110	Caspase-3-like isoform X1; Belongs to the peptidase C14A family. (289 aa)
	LOC106604301	E3 ubiquitin-protein ligase XIAP-like isoform X1. (498 aa)
	LOC106612804	Diablo homolog, mitochondrial-like. (253 aa)
	casp3	Caspase 3B; Belongs to the peptidase C14A family. (311 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP2	LOC106563110	ENSSSAP00000006638	ENSSSAP00000102848	Caspase-2-like; Belongs to the peptidase C14A family.	Caspase-3-like isoform X1; Belongs to the peptidase C14A family.	0.450
CASP2	LOC106566594	ENSSSAP00000006638	ENSSSAP00000047786	Caspase-2-like; Belongs to the peptidase C14A family.	Baculoviral IAP repeat-containing protein 7-like isoform X2.	0.714
CASP2	LOC106567147	ENSSSAP00000006638	ENSSSAP00000099548	Caspase-2-like; Belongs to the peptidase C14A family.	Caspase-9-like; Belongs to the peptidase C14A family.	0.653
CASP2	LOC106569483	ENSSSAP00000006638	ENSSSAP00000051125	Caspase-2-like; Belongs to the peptidase C14A family.	Caspase-8-like; Belongs to the peptidase C14A family.	0.493
CASP2	LOC106572692	ENSSSAP00000006638	ENSSSAP00000012115	Caspase-2-like; Belongs to the peptidase C14A family.	Baculoviral IAP repeat-containing protein 5.1-A-like isoform X2.	0.455
CASP2	LOC106576178	ENSSSAP00000006638	ENSSSAP00000096249	Caspase-2-like; Belongs to the peptidase C14A family.	Death domain-containing protein CRADD-like.	0.921
CASP2	LOC106576445	ENSSSAP00000006638	ENSSSAP00000023412	Caspase-2-like; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1-like isoform X1.	0.862
CASP2	LOC106581203	ENSSSAP00000006638	ENSSSAP00000094591	Caspase-2-like; Belongs to the peptidase C14A family.	Diablo homolog, mitochondrial-like.	0.537
CASP2	LOC106582467	ENSSSAP00000006638	ENSSSAP00000090105	Caspase-2-like; Belongs to the peptidase C14A family.	Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.695
CASP2	LOC106584781	ENSSSAP00000006638	ENSSSAP00000088045	Caspase-2-like; Belongs to the peptidase C14A family.	P53-induced death domain-containing protein 1-like.	0.905
CASP2	LOC106586251	ENSSSAP00000006638	ENSSSAP00000088723	Caspase-2-like; Belongs to the peptidase C14A family.	Cytochrome C; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.695
CASP2	LOC106590758	ENSSSAP00000006638	ENSSSAP00000027738	Caspase-2-like; Belongs to the peptidase C14A family.	Caspase-14-like; Belongs to the peptidase C14A family.	0.419
CASP2	LOC106590759	ENSSSAP00000006638	ENSSSAP00000027790	Caspase-2-like; Belongs to the peptidase C14A family.	Caspase-14-like; Belongs to the peptidase C14A family.	0.444
CASP2	LOC106600607	ENSSSAP00000006638	ENSSSAP00000001582	Caspase-2-like; Belongs to the peptidase C14A family.	Baculoviral IAP repeat-containing protein 7-like isoform X2.	0.714
CASP2	LOC106602722	ENSSSAP00000006638	ENSSSAP00000034454	Caspase-2-like; Belongs to the peptidase C14A family.	Caspase-3-like; Belongs to the peptidase C14A family.	0.493
CASP2	LOC106603345	ENSSSAP00000006638	ENSSSAP00000040200	Caspase-2-like; Belongs to the peptidase C14A family.	Diablo homolog, mitochondrial-like.	0.537
CASP2	LOC106604062	ENSSSAP00000006638	ENSSSAP00000002683	Caspase-2-like; Belongs to the peptidase C14A family.	Inhibitor of apoptosis protein-like isoform X1.	0.714
CASP2	LOC106604301	ENSSSAP00000006638	ENSSSAP00000105342	Caspase-2-like; Belongs to the peptidase C14A family.	E3 ubiquitin-protein ligase XIAP-like isoform X1.	0.768
CASP2	LOC106609292	ENSSSAP00000006638	ENSSSAP00000050549	Caspase-2-like; Belongs to the peptidase C14A family.	Death domain-containing protein CRADD-like.	0.921
CASP2	LOC106609566	ENSSSAP00000006638	ENSSSAP00000053888	Caspase-2-like; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1-like isoform X1.	0.862