(28 nodes) Heteromeric SMAD protein complex, and c-SKI SMAD4-binding domain network (Salmo salar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106563948	Mothers against decapentaplegic homolog. (554 aa)
	ENSSSAP00000011090	SMAD specific E3 ubiquitin protein ligase 2. (621 aa)
	ENSSSAP00000011697	annotation not available (133 aa)
	smad9	Mothers against decapentaplegic homolog. (467 aa)
	LOC106600502	Ski-like protein. (769 aa)
	LOC106569748	Zinc finger FYVE domain-containing protein 9-like. (1177 aa)
	LOC106565969	Ski oncogene-like. (690 aa)
	ENSSSAP00000035223	annotation not available (68 aa)
	LOC106569597	Ski-like protein isoform X1. (760 aa)
	LOC106585370	Mothers against decapentaplegic homolog. (464 aa)
	smad1	Mothers against decapentaplegic homolog. (474 aa)
	LOC106580167	Mothers against decapentaplegic homolog. (579 aa)
	LOC106593023	Mothers against decapentaplegic homolog 6-like. (289 aa)
	LOC106588319	Mothers against decapentaplegic homolog. (587 aa)
	ENSSSAP00000062487	SMAD family member 5. (239 aa)
	smad5	Mothers against decapentaplegic homolog. (468 aa)
	SKI	Ski oncogene-like. (733 aa)
	LOC106568180	Mothers against decapentaplegic homolog. (548 aa)
	ski	Ski oncogene. (729 aa)
	LOC106569881	Mothers against decapentaplegic homolog. (589 aa)
	LOC106582808	Ski oncogene-like. (699 aa)
	ENSSSAP00000097286	annotation not available (86 aa)
	SMAD1	Mothers against decapentaplegic homolog 1-like. (460 aa)
	smad4	Mothers against decapentaplegic homolog. (510 aa)
	LOC106605446	Mothers against decapentaplegic homolog. (565 aa)
	SMAD1-2	Mothers against decapentaplegic homolog. (481 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	LOC106580048	Mothers against decapentaplegic homolog. (467 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSSAP00000011090	ENSSSAP00000011697	ENSSSAP00000011090	ENSSSAP00000011697	SMAD specific E3 ubiquitin protein ligase 2.	annotation not available	0.791
ENSSSAP00000011090	ENSSSAP00000035223	ENSSSAP00000011090	ENSSSAP00000035223	SMAD specific E3 ubiquitin protein ligase 2.	annotation not available	0.791
ENSSSAP00000011090	ENSSSAP00000062487	ENSSSAP00000011090	ENSSSAP00000062487	SMAD specific E3 ubiquitin protein ligase 2.	SMAD family member 5.	0.785
ENSSSAP00000011090	ENSSSAP00000097286	ENSSSAP00000011090	ENSSSAP00000097286	SMAD specific E3 ubiquitin protein ligase 2.	annotation not available	0.791
ENSSSAP00000011090	LOC106563948	ENSSSAP00000011090	ENSSSAP00000001454	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.746
ENSSSAP00000011090	LOC106568180	ENSSSAP00000011090	ENSSSAP00000070778	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.746
ENSSSAP00000011090	LOC106569881	ENSSSAP00000011090	ENSSSAP00000092673	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.746
ENSSSAP00000011090	LOC106580048	ENSSSAP00000011090	ENSSSAP00000114783	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.791
ENSSSAP00000011090	LOC106580167	ENSSSAP00000011090	ENSSSAP00000042739	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.746
ENSSSAP00000011090	LOC106585370	ENSSSAP00000011090	ENSSSAP00000040565	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.791
ENSSSAP00000011090	LOC106588319	ENSSSAP00000011090	ENSSSAP00000061696	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.746
ENSSSAP00000011090	LOC106593023	ENSSSAP00000011090	ENSSSAP00000052701	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog 6-like.	0.877
ENSSSAP00000011090	LOC106605446	ENSSSAP00000011090	ENSSSAP00000102094	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.746
ENSSSAP00000011090	SMAD1	ENSSSAP00000011090	ENSSSAP00000100302	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog 1-like.	0.775
ENSSSAP00000011090	SMAD1-2	ENSSSAP00000011090	ENSSSAP00000103653	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.775
ENSSSAP00000011090	SMAD4	ENSSSAP00000011090	ENSSSAP00000104615	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.746
ENSSSAP00000011090	smad1	ENSSSAP00000011090	ENSSSAP00000040852	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.775
ENSSSAP00000011090	smad4	ENSSSAP00000011090	ENSSSAP00000101532	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.746
ENSSSAP00000011090	smad5	ENSSSAP00000011090	ENSSSAP00000068218	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.785
ENSSSAP00000011090	smad9	ENSSSAP00000011090	ENSSSAP00000016347	SMAD specific E3 ubiquitin protein ligase 2.	Mothers against decapentaplegic homolog.	0.775