(5 nodes) GET complex, and Get1 family network (Salmo salar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106589465	ATPase LOC106589465; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for inse [...] (341 aa)
	ENSSSAP00000028372	annotation not available (164 aa)
	LOC106560687	Calcium signal-modulating cyclophilin ligand-like. (300 aa)
	LOC106612989	Tail-anchored protein insertion receptor WRB-like. (170 aa)
	get1	Tail-anchored protein insertion receptor WRB isoform X1. (170 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSSAP00000028372	LOC106589465	ENSSSAP00000028372	ENSSSAP00000017460	annotation not available	ATPase LOC106589465; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for inse [...]	0.944
ENSSSAP00000028372	LOC106612989	ENSSSAP00000028372	ENSSSAP00000050987	annotation not available	Tail-anchored protein insertion receptor WRB-like.	0.908
ENSSSAP00000028372	get1	ENSSSAP00000028372	ENSSSAP00000108302	annotation not available	Tail-anchored protein insertion receptor WRB isoform X1.	0.908
LOC106560687	LOC106589465	ENSSSAP00000034967	ENSSSAP00000017460	Calcium signal-modulating cyclophilin ligand-like.	ATPase LOC106589465; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for inse [...]	0.944
LOC106560687	LOC106612989	ENSSSAP00000034967	ENSSSAP00000050987	Calcium signal-modulating cyclophilin ligand-like.	Tail-anchored protein insertion receptor WRB-like.	0.908
LOC106560687	get1	ENSSSAP00000034967	ENSSSAP00000108302	Calcium signal-modulating cyclophilin ligand-like.	Tail-anchored protein insertion receptor WRB isoform X1.	0.908
LOC106589465	ENSSSAP00000028372	ENSSSAP00000017460	ENSSSAP00000028372	ATPase LOC106589465; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for inse [...]	annotation not available	0.944
LOC106589465	LOC106560687	ENSSSAP00000017460	ENSSSAP00000034967	ATPase LOC106589465; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for inse [...]	Calcium signal-modulating cyclophilin ligand-like.	0.944
LOC106589465	LOC106612989	ENSSSAP00000017460	ENSSSAP00000050987	ATPase LOC106589465; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for inse [...]	Tail-anchored protein insertion receptor WRB-like.	0.965
LOC106589465	get1	ENSSSAP00000017460	ENSSSAP00000108302	ATPase LOC106589465; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for inse [...]	Tail-anchored protein insertion receptor WRB isoform X1.	0.965
LOC106612989	ENSSSAP00000028372	ENSSSAP00000050987	ENSSSAP00000028372	Tail-anchored protein insertion receptor WRB-like.	annotation not available	0.908
LOC106612989	LOC106560687	ENSSSAP00000050987	ENSSSAP00000034967	Tail-anchored protein insertion receptor WRB-like.	Calcium signal-modulating cyclophilin ligand-like.	0.908
LOC106612989	LOC106589465	ENSSSAP00000050987	ENSSSAP00000017460	Tail-anchored protein insertion receptor WRB-like.	ATPase LOC106589465; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for inse [...]	0.965
get1	ENSSSAP00000028372	ENSSSAP00000108302	ENSSSAP00000028372	Tail-anchored protein insertion receptor WRB isoform X1.	annotation not available	0.908
get1	LOC106560687	ENSSSAP00000108302	ENSSSAP00000034967	Tail-anchored protein insertion receptor WRB isoform X1.	Calcium signal-modulating cyclophilin ligand-like.	0.908
get1	LOC106589465	ENSSSAP00000108302	ENSSSAP00000017460	Tail-anchored protein insertion receptor WRB isoform X1.	ATPase LOC106589465; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for inse [...]	0.965