(33 nodes) Mixed, incl. NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis, and Domain of unknown function (DUF4927) network (Salmo salar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106606082	Retinoic acid receptor RXR-beta-A-like isoform X1. (424 aa)
	LOC100136378	Nuclear receptor subfamily 1 group D member 2. (596 aa)
	LOC106573302	Bile acid receptor-like isoform X1. (487 aa)
	LOC106565233	Vitamin D3 receptor B isoform X1. (449 aa)
	pparg	Peroxisome proliferator-activated receptor gamma isoform X1. (543 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha isoform X1. (477 aa)
	LOC106566754	Peroxisome proliferator-activated receptor gamma-like isoform X1. (662 aa)
	nr1h4	Bile acid receptor. (580 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma-like. (635 aa)
	LOC106582110	Nuclear receptor subfamily 1 group D member 2-like. (647 aa)
	LOC106571447	Nuclear receptor coactivator 1-like. (1444 aa)
	LOC106569952	Retinoic acid receptor RXR-beta-A-like. (469 aa)
	LOC106565394	Retinoic acid receptor RXR-alpha-A-like. (595 aa)
	LOC106588668	Nuclear receptor subfamily 1 group D member 2-like isoform X1. (649 aa)
	ENSSSAP00000058164	Retinoic acid receptor RXR-gamma-B-like. (307 aa)
	LOC106570286	Nuclear receptor subfamily 1 group D member 2-like isoform X1. (635 aa)
	ENSSSAP00000062034	annotation not available (76 aa)
	LOC106561422	Bile acid receptor-like isoform X1. (492 aa)
	PPARA-2	Peroxisome proliferator-activated receptor alpha-like. (479 aa)
	LOC106571934	Nuclear receptor coactivator 3-like isoform X1. (1613 aa)
	LOC106586651	Nuclear receptor subfamily 1 group I member 2-like isoform X3. (450 aa)
	NCOA3	Nuclear receptor coactivator 3-like. (1546 aa)
	LOC106561932	Oxysterols receptor LXR-alpha-like isoform X4. (464 aa)
	rxra	Retinoic acid receptor RXR-alpha isoform X1. (531 aa)
	NCOA2	Nuclear receptor coactivator 2-like. (1537 aa)
	LOC100136371	Vitamin D3 receptor B isoform X2. (453 aa)
	LOC106563228	Retinoic acid receptor RXR-alpha-A isoform X3. (523 aa)
	LOC106566896	Vitamin D3 receptor A-like. (431 aa)
	nr1h3	Salmo salar nuclear receptor subfamily 1 group H member 3 (nr1h3), mRNA. (470 aa)
	LOC106607631	Nuclear receptor coactivator 1-like. (1585 aa)
	NCOA2-2	Nuclear receptor coactivator 2-like isoform X1. (1550 aa)
	LOC106588394	Retinoic acid receptor RXR-beta-A isoform X2. (493 aa)
	LOC106582905	Nuclear receptor coactivator 3-like isoform X1. (1522 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSSAP00000058164	LOC100136371	ENSSSAP00000058164	ENSSSAP00000082108	Retinoic acid receptor RXR-gamma-B-like.	Vitamin D3 receptor B isoform X2.	0.729
ENSSSAP00000058164	LOC100136378	ENSSSAP00000058164	ENSSSAP00000010017	Retinoic acid receptor RXR-gamma-B-like.	Nuclear receptor subfamily 1 group D member 2.	0.443
ENSSSAP00000058164	LOC106561422	ENSSSAP00000058164	ENSSSAP00000062630	Retinoic acid receptor RXR-gamma-B-like.	Bile acid receptor-like isoform X1.	0.819
ENSSSAP00000058164	LOC106561932	ENSSSAP00000058164	ENSSSAP00000078652	Retinoic acid receptor RXR-gamma-B-like.	Oxysterols receptor LXR-alpha-like isoform X4.	0.876
ENSSSAP00000058164	LOC106565233	ENSSSAP00000058164	ENSSSAP00000016423	Retinoic acid receptor RXR-gamma-B-like.	Vitamin D3 receptor B isoform X1.	0.729
ENSSSAP00000058164	LOC106566754	ENSSSAP00000058164	ENSSSAP00000024290	Retinoic acid receptor RXR-gamma-B-like.	Peroxisome proliferator-activated receptor gamma-like isoform X1.	0.716
ENSSSAP00000058164	LOC106566896	ENSSSAP00000058164	ENSSSAP00000093175	Retinoic acid receptor RXR-gamma-B-like.	Vitamin D3 receptor A-like.	0.729
ENSSSAP00000058164	LOC106570286	ENSSSAP00000058164	ENSSSAP00000060872	Retinoic acid receptor RXR-gamma-B-like.	Nuclear receptor subfamily 1 group D member 2-like isoform X1.	0.443
ENSSSAP00000058164	LOC106571447	ENSSSAP00000058164	ENSSSAP00000030596	Retinoic acid receptor RXR-gamma-B-like.	Nuclear receptor coactivator 1-like.	0.739
ENSSSAP00000058164	LOC106571934	ENSSSAP00000058164	ENSSSAP00000074668	Retinoic acid receptor RXR-gamma-B-like.	Nuclear receptor coactivator 3-like isoform X1.	0.739
ENSSSAP00000058164	LOC106573302	ENSSSAP00000058164	ENSSSAP00000013765	Retinoic acid receptor RXR-gamma-B-like.	Bile acid receptor-like isoform X1.	0.819
ENSSSAP00000058164	LOC106582110	ENSSSAP00000058164	ENSSSAP00000028616	Retinoic acid receptor RXR-gamma-B-like.	Nuclear receptor subfamily 1 group D member 2-like.	0.443
ENSSSAP00000058164	LOC106582905	ENSSSAP00000058164	ENSSSAP00000120712	Retinoic acid receptor RXR-gamma-B-like.	Nuclear receptor coactivator 3-like isoform X1.	0.739
ENSSSAP00000058164	LOC106586651	ENSSSAP00000058164	ENSSSAP00000075889	Retinoic acid receptor RXR-gamma-B-like.	Nuclear receptor subfamily 1 group I member 2-like isoform X3.	0.759
ENSSSAP00000058164	LOC106588668	ENSSSAP00000058164	ENSSSAP00000057644	Retinoic acid receptor RXR-gamma-B-like.	Nuclear receptor subfamily 1 group D member 2-like isoform X1.	0.443
ENSSSAP00000058164	LOC106607631	ENSSSAP00000058164	ENSSSAP00000106481	Retinoic acid receptor RXR-gamma-B-like.	Nuclear receptor coactivator 1-like.	0.739
ENSSSAP00000058164	NCOA2	ENSSSAP00000058164	ENSSSAP00000079582	Retinoic acid receptor RXR-gamma-B-like.	Nuclear receptor coactivator 2-like.	0.739
ENSSSAP00000058164	NCOA2-2	ENSSSAP00000058164	ENSSSAP00000111498	Retinoic acid receptor RXR-gamma-B-like.	Nuclear receptor coactivator 2-like isoform X1.	0.739
ENSSSAP00000058164	NCOA3	ENSSSAP00000058164	ENSSSAP00000077256	Retinoic acid receptor RXR-gamma-B-like.	Nuclear receptor coactivator 3-like.	0.739
ENSSSAP00000058164	PPARA	ENSSSAP00000058164	ENSSSAP00000018830	Retinoic acid receptor RXR-gamma-B-like.	Peroxisome proliferator-activated receptor alpha isoform X1.	0.716