32 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106613226	Secreted frizzled-related protein 2-like. (317 aa)
	LOC106575767	Homeobox protein GBX-2-like. (359 aa)
	LOC106610025	Secreted frizzled-related protein 2-like. (293 aa)
	LOC106570392	Endothelin-1-like. (203 aa)
	LOC106561514	Notch-regulated ankyrin repeat-containing protein A. (112 aa)
	ENSSSAP00000026413	annotation not available (228 aa)
	LOC106575767-2	Homeobox protein GBX-2-like. (341 aa)
	ENSSSAP00000028991	annotation not available (186 aa)
	LOC106605015	Vascular endothelial growth factor A-A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (190 aa)
	LOC106586056	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (486 aa)
	LOC106568448	Notch-regulated ankyrin repeat-containing protein A-like. (112 aa)
	LOC106578207	Endothelin-1 receptor-like. (222 aa)
	lef1	Lymphoid enhancer-binding factor 1 isoform X5. (408 aa)
	LOC106567354	serine--tRNA ligase, cytoplasmic-like. (513 aa)
	LOC106589028	Uncharacterized protein LOC106589028. (275 aa)
	LOC106584182	Vascular endothelial growth factor A-A isoform X1; Belongs to the PDGF/VEGF growth factor family. (190 aa)
	nfatc4	Nuclear factor of activated T-cells, cytoplasmic 4. (891 aa)
	LOC100380679	Calcineurin subunit B type 1. (185 aa)
	LOC106612108	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (481 aa)
	tgfr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (549 aa)
	LOC106564784	Serum response factor-like isoform X1. (528 aa)
	LOC106572754	serine--tRNA ligase, cytoplasmic-like. (527 aa)
	LOC106610223	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family. (481 aa)
	SRF	Serum response factor-like isoform X1. (596 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (571 aa)
	LOC106576882	Serum response factor-like isoform X4. (566 aa)
	LOC106578839	Calcineurin subunit B type 1-like. (274 aa)
	LOC106606173	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (582 aa)
	LOC106602749	Secreted frizzled-related protein 2-like. (293 aa)
	LOC106584839	Serum response factor-like isoform X1. (529 aa)
	LOC106586010	Calcineurin subunit B type 1. (196 aa)
	NFATC4	Nuclear factor of activated T-cells, cytoplasmic 4-like isoform X2. (891 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100380679	NFATC4	ENSSSAP00000085262	ENSSSAP00000072279	Calcineurin subunit B type 1.	Nuclear factor of activated T-cells, cytoplasmic 4-like isoform X2.	0.791
LOC100380679	nfatc4	ENSSSAP00000085262	ENSSSAP00000011584	Calcineurin subunit B type 1.	Nuclear factor of activated T-cells, cytoplasmic 4.	0.791
LOC106567354	LOC106572754	ENSSSAP00000076617	ENSSSAP00000101747	serine--tRNA ligase, cytoplasmic-like.	serine--tRNA ligase, cytoplasmic-like.	0.900
LOC106570392	LOC106578207	ENSSSAP00000019078	ENSSSAP00000041268	Endothelin-1-like.	Endothelin-1 receptor-like.	0.985
LOC106570392	LOC106589028	ENSSSAP00000019078	ENSSSAP00000076828	Endothelin-1-like.	Uncharacterized protein LOC106589028.	0.900
LOC106570392	LOC106610223	ENSSSAP00000019078	ENSSSAP00000104145	Endothelin-1-like.	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.998
LOC106572754	LOC106567354	ENSSSAP00000101747	ENSSSAP00000076617	serine--tRNA ligase, cytoplasmic-like.	serine--tRNA ligase, cytoplasmic-like.	0.900
LOC106578207	LOC106570392	ENSSSAP00000041268	ENSSSAP00000019078	Endothelin-1 receptor-like.	Endothelin-1-like.	0.985
LOC106578207	LOC106589028	ENSSSAP00000041268	ENSSSAP00000076828	Endothelin-1 receptor-like.	Uncharacterized protein LOC106589028.	0.985
LOC106578839	NFATC4	ENSSSAP00000111959	ENSSSAP00000072279	Calcineurin subunit B type 1-like.	Nuclear factor of activated T-cells, cytoplasmic 4-like isoform X2.	0.791
LOC106578839	nfatc4	ENSSSAP00000111959	ENSSSAP00000011584	Calcineurin subunit B type 1-like.	Nuclear factor of activated T-cells, cytoplasmic 4.	0.791
LOC106584182	LOC106605015	ENSSSAP00000083654	ENSSSAP00000074586	Vascular endothelial growth factor A-A isoform X1; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor A-A-like isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.900
LOC106586010	NFATC4	ENSSSAP00000055181	ENSSSAP00000072279	Calcineurin subunit B type 1.	Nuclear factor of activated T-cells, cytoplasmic 4-like isoform X2.	0.430
LOC106586010	nfatc4	ENSSSAP00000055181	ENSSSAP00000011584	Calcineurin subunit B type 1.	Nuclear factor of activated T-cells, cytoplasmic 4.	0.430
LOC106586056	LOC106612108	ENSSSAP00000035298	ENSSSAP00000090137	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	0.900
LOC106589028	LOC106570392	ENSSSAP00000076828	ENSSSAP00000019078	Uncharacterized protein LOC106589028.	Endothelin-1-like.	0.900
LOC106589028	LOC106578207	ENSSSAP00000076828	ENSSSAP00000041268	Uncharacterized protein LOC106589028.	Endothelin-1 receptor-like.	0.985
LOC106589028	LOC106610223	ENSSSAP00000076828	ENSSSAP00000104145	Uncharacterized protein LOC106589028.	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.998
LOC106602749	lef1	ENSSSAP00000010091	ENSSSAP00000048989	Secreted frizzled-related protein 2-like.	Lymphoid enhancer-binding factor 1 isoform X5.	0.526
LOC106605015	LOC106584182	ENSSSAP00000074586	ENSSSAP00000083654	Vascular endothelial growth factor A-A-like isoform X1; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor A-A isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.900