STRINGSTRING
isg20l2 isg20l2 exd2 exd2 LOC106594599 LOC106594599 LOC106594655 LOC106594655 LOC106594665 LOC106594665 LOC106595461 LOC106595461 LOC106602922 LOC106602922 LOC106599786 LOC106599786 ENSSSAP00000004382 ENSSSAP00000004382 LOC106593600 LOC106593600 PLD4 PLD4 ENSSSAP00000008190 ENSSSAP00000008190 LOC106597766 LOC106597766 DXO DXO ENSSSAP00000009720 ENSSSAP00000009720 dis3l2 dis3l2 ENSSSAP00000010521 ENSSSAP00000010521 meiob meiob LOC106611868 LOC106611868 LOC106603492 LOC106603492 LOC106576591 LOC106576591 LOC106576591-2 LOC106576591-2 LOC106563692 LOC106563692 zc3h12a zc3h12a ISG20L2 ISG20L2 LOC106584653 LOC106584653 LOC106591874 LOC106591874 LOC106597766-2 LOC106597766-2 LOC106596388 LOC106596388 LOC106613849 LOC106613849 PNPT1 PNPT1 pde12 pde12 ENSSSAP00000027284 ENSSSAP00000027284 ENSSSAP00000028050 ENSSSAP00000028050 LOC106573026 LOC106573026 TRIR TRIR tatdn1 tatdn1 LOC106601920 LOC106601920 ENSSSAP00000035080 ENSSSAP00000035080 exd3 exd3 LOC106606733 LOC106606733 wrn wrn LOC106612700 LOC106612700 ENSSSAP00000038656 ENSSSAP00000038656 ENSSSAP00000039085 ENSSSAP00000039085 pan2 pan2 ENSSSAP00000039471 ENSSSAP00000039471 LOC106611069 LOC106611069 ENSSSAP00000042491 ENSSSAP00000042491 ENSSSAP00000044045 ENSSSAP00000044045 LOC106583205 LOC106583205 DPOD1 DPOD1 ENSSSAP00000047854 ENSSSAP00000047854 apex1 apex1 LOC106604834 LOC106604834 toe1 toe1 LOC106611057 LOC106611057 rad9a rad9a LOC106584366 LOC106584366 exo5 exo5 ENSSSAP00000062721 ENSSSAP00000062721 RAD1 RAD1 cnot8 cnot8 LOC106612271 LOC106612271 LOC106591161 LOC106591161 MRE11 MRE11 dclre1b dclre1b LOC100380685 LOC100380685 LOC106599575 LOC106599575 tdp1 tdp1 polg polg Mre11 Mre11 LOC106604687 LOC106604687 LOC100380852 LOC100380852 cnot6 cnot6 LOC106589020 LOC106589020 apex2 apex2 ENSSSAP00000080183 ENSSSAP00000080183 rexo2 rexo2 LOC106601332 LOC106601332 LOC106593293 LOC106593293 pole pole aplf aplf pld3 pld3 dcp2 dcp2 dclre1a dclre1a LOC106571262 LOC106571262 rexo4 rexo4 LOC106605117 LOC106605117 ENSSSAP00000089669 ENSSSAP00000089669 fan1 fan1 thex1 thex1 LOC106567314 LOC106567314 LOC106585873 LOC106585873 ENSSSAP00000093095 ENSSSAP00000093095 angel2 angel2 usb1 usb1 cpsf3 cpsf3 i20l1 i20l1 LOC106570868 LOC106570868 PNPT1-2 PNPT1-2 aptx aptx LOC100380636 LOC100380636 exo1 exo1 LOC106568870 LOC106568870 ENSSSAP00000105766 ENSSSAP00000105766 LOC106571209 LOC106571209 mgme1 mgme1 LOC106568724 LOC106568724 FEN1 FEN1 ENSSSAP00000112721 ENSSSAP00000112721 rad9b rad9b exosc10 exosc10 LOC106597535 LOC106597535 LOC106588363 LOC106588363 LOC106599369 LOC106599369 dis3 dis3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
isg20l2Interferon-stimulated 20 kDa exonuclease-like 2. (336 aa)
exd2Exonuclease 3'-5' domain-containing protein 2. (421 aa)
LOC106594599Putative RNA exonuclease NEF-sp. (421 aa)
LOC106594655ERI1 exoribonuclease 2-like. (883 aa)
LOC106594665Putative RNA exonuclease NEF-sp. (770 aa)
LOC106595461Zinc finger protein 197-like isoform X1. (605 aa)
LOC106602922CCR4-NOT transcription complex subunit 6-like. (560 aa)
LOC106599786Exonuclease 3'-5' domain-containing protein 1-like isoform X2. (275 aa)
ENSSSAP00000004382annotation not available (666 aa)
LOC106593600poly(A)-specific ribonuclease PARN-like. (753 aa)
PLD4Phospholipase D4-like. (519 aa)
ENSSSAP00000008190Nocturnin b. (388 aa)
LOC106597766Nocturnin-like. (405 aa)
DXODecapping and exoribonuclease protein-like. (439 aa)
ENSSSAP00000009720annotation not available (632 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1049 aa)
ENSSSAP00000010521annotation not available (551 aa)
meiobMeiosis-specific with OB domain-containing protein isoform X1. (464 aa)
LOC106611868CCR4-NOT transcription complex subunit 6-like isoform X1. (583 aa)
LOC106603492CCR4-NOT transcription complex subunit 7 isoform X2. (300 aa)
LOC106576591DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (342 aa)
LOC106576591-2DNA-(apurinic or apyrimidinic site) lyase-like. (342 aa)
LOC1065636923'-5' exoribonuclease 1-like isoform X1. (337 aa)
zc3h12aRibonuclease ZC3H12A. (615 aa)
ISG20L2Interferon-stimulated 20 kDa exonuclease-like 2. (333 aa)
LOC106584653Apoptosis-enhancing nuclease-like. (368 aa)
LOC106591874Exonuclease 3'-5' domain-containing protein 2-like. (550 aa)
LOC106597766-2Nocturnin-like. (405 aa)
LOC106596388Nocturnin-like. (405 aa)
LOC106613849RNA exonuclease 1 homolog. (1313 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1, mitochondrial-like. (779 aa)
pde122',5'-phosphodiesterase 12. (586 aa)
ENSSSAP00000027284annotation not available (97 aa)
ENSSSAP00000028050Telomerase RNA component interacting RNase. (101 aa)
LOC106573026Ectonucleotide pyrophosphatase/phosphodiesterase family member 2-like. (269 aa)
TRIRTelomerase RNA component interacting RNase. (99 aa)
tatdn1Putative deoxyribonuclease TATDN1 isoform X1. (324 aa)
LOC106601920DNA polymerase delta catalytic subunit-like. (681 aa)
ENSSSAP00000035080annotation not available (383 aa)
exd3Exonuclease mut-7 homolog isoform X1. (896 aa)
LOC106606733Decapping and exoribonuclease protein-like. (439 aa)
wrnWerner syndrome ATP-dependent helicase isoform X2. (1467 aa)
LOC106612700Phospholipase D3-like. (504 aa)
ENSSSAP00000038656annotation not available (72 aa)
ENSSSAP00000039085annotation not available (179 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1197 aa)
ENSSSAP00000039471annotation not available (491 aa)
LOC106611069Exonuclease 3'-5' domain-containing protein 1-like. (601 aa)
ENSSSAP00000042491annotation not available (750 aa)
ENSSSAP00000044045annotation not available (168 aa)
LOC106583205Ribonuclease ZC3H12A-like. (671 aa)
DPOD1DNA polymerase. (899 aa)
ENSSSAP00000047854annotation not available (265 aa)
apex1Salmo salar APEX nuclease (multifunctional DNA repair enzyme) 1 (apex1), mRNA. (344 aa)
LOC106604834CCR4-NOT transcription complex subunit 6-like. (568 aa)
toe1Target of EGR1 protein 1. (528 aa)
LOC106611057Protein angel homolog 1-like isoform X1. (803 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (393 aa)
LOC106584366RNA exonuclease 1 homolog. (1298 aa)
exo5Exonuclease V. (322 aa)
ENSSSAP00000062721annotation not available (344 aa)
RAD1Cell cycle checkpoint protein RAD1. (279 aa)
cnot8CCR4-NOT transcription complex subunit 8. (285 aa)
LOC106612271Uncharacterized protein LOC106612271 isoform X1. (868 aa)
LOC106591161LOW QUALITY PROTEIN: DIS3-like exonuclease 1. (626 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (474 aa)
dclre1b5' exonuclease Apollo isoform X1. (704 aa)
LOC100380685Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X2. (855 aa)
LOC1065995755'-3' exoribonuclease 1. (1698 aa)
tdp1tyrosyl-DNA phosphodiesterase 1 isoform X1. (644 aa)
polgDNA polymerase subunit gamma-1. (1202 aa)
Mre11MRE11 homolog, double strand break repair nuclease. (452 aa)
LOC106604687Nocturnin-like isoform X1. (474 aa)
LOC100380852Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (907 aa)
cnot6CCR4-NOT transcription complex, subunit 6 isoform X2. (557 aa)
LOC106589020Ribonuclease ZC3H12A-like. (700 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (601 aa)
ENSSSAP00000080183annotation not available (109 aa)
rexo2Oligoribonuclease, mitochondrial. (289 aa)
LOC106601332Uncharacterized protein C19orf43-like. (168 aa)
LOC106593293ATP-dependent RNA helicase DDX1-like. (403 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2292 aa)
aplfAprataxin and PNK-like factor isoform X1. (356 aa)
pld3Phospholipase D family member 3. (495 aa)
dcp2m7GpppN-mRNA hydrolase isoform X1. (402 aa)
dclre1aDNA cross-link repair 1A protein. (898 aa)
LOC1065712625'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (959 aa)
rexo4REX4, RNA exonuclease 4 homolog isoform X1. (444 aa)
LOC106605117Ribonuclease ZC3H12A-like. (662 aa)
ENSSSAP00000089669annotation not available (491 aa)
fan1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1075 aa)
thex1Histone mRNA 3-exonuclease 1. (346 aa)
LOC106567314DNA-(Apurinic or apyrimidinic site) lyase 2-like. (299 aa)
LOC106585873CCR4-NOT transcription complex subunit 6-like isoform X1. (600 aa)
ENSSSAP00000093095annotation not available (250 aa)
angel2Protein angel homolog 2 isoform X2. (583 aa)
usb1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (320 aa)
cpsf3Cleavage and polyadenylation specificity factor subunit 3. (692 aa)
i20l1Interferon-stimulated 20 kDa exonuclease-like 1 isoform X1. (378 aa)
LOC106570868CCR4-NOT transcription complex subunit 6-like isoform X1. (570 aa)
PNPT1-2Polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1. (777 aa)
aptxAprataxin. (348 aa)
LOC1003806365'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (953 aa)
exo1Exonuclease 1. (786 aa)
LOC1065688705'-3' exoribonuclease 1. (1695 aa)
ENSSSAP00000105766annotation not available (252 aa)
LOC106571209Ectonucleotide pyrophosphatase/phosphodiesterase family member 3-like. (802 aa)
mgme1Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family. (353 aa)
LOC106568724RNA exonuclease 4-like. (491 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (402 aa)
ENSSSAP00000112721annotation not available (332 aa)
rad9bCell cycle checkpoint control protein RAD9B. (301 aa)
exosc10Exosome component 10. (1008 aa)
LOC106597535Ectonucleotide pyrophosphatase/phosphodiesterase family member 2-like. (870 aa)
LOC106588363Venom phosphodiesterase 1-like. (867 aa)
LOC106599369Target of EGR1 protein 1-like. (510 aa)
dis3Exosome complex exonuclease RRP44 isoform X1; Belongs to the RNR ribonuclease family. (949 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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