STRINGSTRING
SMARCAL1 SMARCAL1 LOC106612933 LOC106612933 hmces hmces LOC106565575 LOC106565575 pold3 pold3 pold4 pold4 LOC106601920 LOC106601920 tonsl tonsl LOC106609896 LOC106609896 pola2 pola2 prim2 prim2 rfc3 rfc3 LOC106583181 LOC106583181 ENSSSAP00000019926 ENSSSAP00000019926 LOC106607210 LOC106607210 xrcc3 xrcc3 ENSSSAP00000017215 ENSSSAP00000017215 LOC106575916 LOC106575916 chek1 chek1 rfc2 rfc2 primpol primpol ENSSSAP00000115911 ENSSSAP00000115911 TEX264 TEX264 MRE11 MRE11 rad51c rad51c prp19 prp19 pola1 pola1 radx radx polh polh ENSSSAP00000109661 ENSSSAP00000109661 donson donson rad51d rad51d wrn wrn tipin tipin LOC100380772 LOC100380772 dmap1 dmap1 LOC106574092 LOC106574092 DPOD1 DPOD1 LOC106562517 LOC106562517 rfa1 rfa1 ENSSSAP00000052068 ENSSSAP00000052068 mcm10 mcm10 rad18 rad18 ENSSSAP00000059858 ENSSSAP00000059858 Mre11 Mre11 timeless timeless ENSSSAP00000075319 ENSSSAP00000075319 prim1 prim1 ENSSSAP00000079200 ENSSSAP00000079200 mms22l mms22l rfc5 rfc5 LOC106611702 LOC106611702 ENSSSAP00000088520 ENSSSAP00000088520 rpa3 rpa3 rfc4 rfc4 ENSSSAP00000090923 ENSSSAP00000090923 ENSSSAP00000093833 ENSSSAP00000093833 LOC106613510 LOC106613510 LOC106570310 LOC106570310 XRCC2 XRCC2 pold2 pold2 rad51b rad51b ENSSSAP00000101078 ENSSSAP00000101078 wdhd1 wdhd1 MCM10 MCM10 pif1 pif1 ENSSSAP00000102908 ENSSSAP00000102908 LOC106583187 LOC106583187
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMARCAL1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1. (560 aa)
LOC106612933Replication protein A 70 kDa DNA-binding subunit-like. (632 aa)
hmcesAbasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (363 aa)
LOC106565575Testis-expressed sequence 264 protein-like. (332 aa)
pold3DNA polymerase delta subunit 3 isoform X1. (449 aa)
pold4DNA polymerase subunit delta-4. (125 aa)
LOC106601920DNA polymerase delta catalytic subunit-like. (681 aa)
tonslTonsoku-like protein. (1433 aa)
LOC106609896pre-mRNA-processing factor 19. (505 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (617 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (515 aa)
rfc3Replication factor C subunit 3 isoform X1. (334 aa)
LOC106583181E3 ubiquitin-protein ligase RAD18-like isoform X1. (584 aa)
ENSSSAP00000019926annotation not available (202 aa)
LOC106607210DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1527 aa)
xrcc3DNA repair protein XRCC3. (371 aa)
ENSSSAP00000017215annotation not available (115 aa)
LOC106575916DNA annealing helicase and endonuclease ZRANB3-like isoform X1. (523 aa)
chek1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (480 aa)
rfc2Replication factor C subunit 2. (381 aa)
primpolDNA-directed primase/polymerase protein. (528 aa)
ENSSSAP00000115911annotation not available (260 aa)
TEX264Testis-expressed sequence 264 protein-like. (319 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (474 aa)
rad51cDNA repair protein RAD51 homolog 3. (400 aa)
prp19Pre-mRNA-processing factor 19. (505 aa)
pola1DNA polymerase. (1466 aa)
radxUncharacterized protein CXorf57 homolog isoform X1. (870 aa)
polhDNA polymerase eta. (782 aa)
ENSSSAP00000109661DNA primase subunit 2. (432 aa)
donsonProtein downstream neighbor of Son. (605 aa)
rad51dDNA repair protein RAD51 homolog 4. (336 aa)
wrnWerner syndrome ATP-dependent helicase isoform X2. (1467 aa)
tipinTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (301 aa)
LOC100380772DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1531 aa)
dmap1DNA methyltransferase 1-associated protein 1 isoform X2. (490 aa)
LOC106574092E3 ubiquitin-protein ligase UHRF1-like. (828 aa)
DPOD1DNA polymerase. (899 aa)
LOC106562517Tumor suppressor p53-binding protein 1-like isoform X3. (1923 aa)
rfa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
ENSSSAP00000052068annotation not available (370 aa)
mcm10Protein MCM10 homolog isoform X1. (934 aa)
rad18E3 ubiquitin-protein ligase RAD18 isoform X2. (501 aa)
ENSSSAP00000059858annotation not available (300 aa)
Mre11MRE11 homolog, double strand break repair nuclease. (452 aa)
timelessProtein timeless homolog. (1252 aa)
ENSSSAP00000075319annotation not available (299 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (476 aa)
ENSSSAP00000079200Replication factor C (activator 1) 2. (372 aa)
mms22lProtein MMS22-like isoform X1. (1314 aa)
rfc5Replication factor C subunit 5. (341 aa)
LOC106611702pre-mRNA-processing factor 19-like. (505 aa)
ENSSSAP00000088520Replication factor C (activator 1) 5. (305 aa)
rpa3Replication protein A3. (159 aa)
rfc4Replication factor C subunit 4 isoform X1. (361 aa)
ENSSSAP00000090923annotation not available (91 aa)
ENSSSAP00000093833annotation not available (134 aa)
LOC106613510E3 ubiquitin-protein ligase UHRF1. (788 aa)
LOC106570310Replication protein A 14 kDa subunit-like. (147 aa)
XRCC2DNA repair protein XRCC2-like. (307 aa)
pold2DNA polymerase subunit delta-2. (500 aa)
rad51bDNA repair protein RAD51 homolog 2 isoform X1. (418 aa)
ENSSSAP00000101078annotation not available (498 aa)
wdhd1WD repeat and HMG-box DNA-binding protein 1 isoform X1. (1169 aa)
MCM10Minichromosome maintenance 10 replication initiation factor. (706 aa)
pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (650 aa)
ENSSSAP00000102908annotation not available (83 aa)
LOC106583187Testis-expressed sequence 264 protein-like isoform X1. (347 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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