STRINGSTRING
ENSSSAP00000082560 ENSSSAP00000082560 lig1 lig1 smug1 smug1 sirt6 sirt6 ENSSSAP00000115415 ENSSSAP00000115415 ercc6 ercc6 ENSSSAP00000114968 ENSSSAP00000114968 ENSSSAP00000112721 ENSSSAP00000112721 FEN1 FEN1 ogg1 ogg1 ENSSSAP00000106605 ENSSSAP00000106605 ENSSSAP00000105766 ENSSSAP00000105766 LOC106587191 LOC106587191 mutyh mutyh xpa-2 xpa-2 neil3 neil3 LOC106570310 LOC106570310 LOC106567314 LOC106567314 LOC106562100 LOC106562100 rpa3 rpa3 ENSSSAP00000085653 ENSSSAP00000085653 pole pole LOC106582635 LOC106582635 DNA2 DNA2 apex2 apex2 ung ung polg polg LOC106567026 LOC106567026 LOC106601084 LOC106601084 xpa xpa lig3 lig3 LOC106605164 LOC106605164 apex1 apex1 DPOD1 DPOD1 polb polb LOC106580473 LOC106580473 LOC106607370 LOC106607370 ENSSSAP00000042491 ENSSSAP00000042491 ENSSSAP00000038656 ENSSSAP00000038656 wrn wrn LOC106565999 LOC106565999 ENSSSAP00000035080 ENSSSAP00000035080 LOC106601920 LOC106601920 ENSSSAP00000030974 ENSSSAP00000030974 LOC106561087 LOC106561087 ENSSSAP00000028256 ENSSSAP00000028256 LOC100380641 LOC100380641 LOC106584662 LOC106584662 LOC106584663 LOC106584663 neil1-2 neil1-2 neil1 neil1 LOC106564589 LOC106564589 LOC106576591-2 LOC106576591-2 LOC106576591 LOC106576591 LOC106564287 LOC106564287 parp2 parp2 ENSSSAP00000011115 ENSSSAP00000011115 ENSSSAP00000005631 ENSSSAP00000005631 LOC106591641 LOC106591641 LOC106588764 LOC106588764
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSSSAP00000082560annotation not available (696 aa)
lig1DNA ligase. (1088 aa)
smug1Single-strand selective monofunctional uracil DNA glycosylase. (297 aa)
sirt6NAD-dependent protein deacetylase sirtuin-6 isoform X1. (383 aa)
ENSSSAP00000115415annotation not available (257 aa)
ercc6DNA excision repair protein ERCC-6. (1488 aa)
ENSSSAP00000114968annotation not available (273 aa)
ENSSSAP00000112721annotation not available (332 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (402 aa)
ogg1N-glycosylase/DNA lyase isoform X1. (440 aa)
ENSSSAP00000106605annotation not available (938 aa)
ENSSSAP00000105766annotation not available (252 aa)
LOC106587191Ubiquitin carboxyl-terminal hydrolase 47-like isoform X2; Belongs to the peptidase C19 family. (1394 aa)
mutyhAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (523 aa)
xpa-2DNA repair protein complementing XP-A cells. (278 aa)
neil3Endonuclease 8-like 3. (589 aa)
LOC106570310Replication protein A 14 kDa subunit-like. (147 aa)
LOC106567314DNA-(Apurinic or apyrimidinic site) lyase 2-like. (299 aa)
LOC106562100Ubiquitin carboxyl-terminal hydrolase 47-like isoform X3; Belongs to the peptidase C19 family. (1389 aa)
rpa3Replication protein A3. (159 aa)
ENSSSAP00000085653annotation not available (82 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2292 aa)
LOC106582635DNA repair protein XRCC1-like. (633 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2. (1073 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (601 aa)
ungUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (64 aa)
polgDNA polymerase subunit gamma-1. (1202 aa)
LOC106567026E3 ubiquitin-protein ligase HUWE1-like isoform X16. (4488 aa)
LOC106601084DNA-3-methyladenine glycosylase-like isoform X1. (271 aa)
xpaDNA-repair protein complementing XP-A cells homolog. (274 aa)
lig3DNA ligase. (1023 aa)
LOC106605164DNA repair protein XRCC1-like. (989 aa)
apex1Salmo salar APEX nuclease (multifunctional DNA repair enzyme) 1 (apex1), mRNA. (344 aa)
DPOD1DNA polymerase. (899 aa)
polbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (344 aa)
LOC106580473DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (312 aa)
LOC106607370DNA-3-methyladenine glycosylase-like isoform X1. (300 aa)
ENSSSAP00000042491annotation not available (750 aa)
ENSSSAP00000038656annotation not available (72 aa)
wrnWerner syndrome ATP-dependent helicase isoform X2. (1467 aa)
LOC106565999High mobility group protein HMGI-C-like. (87 aa)
ENSSSAP00000035080annotation not available (383 aa)
LOC106601920DNA polymerase delta catalytic subunit-like. (681 aa)
ENSSSAP00000030974annotation not available (354 aa)
LOC106561087G/T mismatch-specific thymine DNA glycosylase-like isoform X1. (467 aa)
ENSSSAP00000028256annotation not available (817 aa)
LOC100380641E3 ubiquitin-protein ligase HUWE1 isoform X13. (4542 aa)
LOC106584662G/T mismatch-specific thymine DNA glycosylase-like isoform X1. (436 aa)
LOC106584663G/T mismatch-specific thymine DNA glycosylase-like isoform X1. (457 aa)
neil1-2Endonuclease 8-like 1 isoform X1. (151 aa)
neil1Endonuclease 8-like 1 isoform X2. (421 aa)
LOC106564589DNA polymerase lambda-like; Belongs to the DNA polymerase type-X family. (565 aa)
LOC106576591-2DNA-(apurinic or apyrimidinic site) lyase-like. (342 aa)
LOC106576591DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (342 aa)
LOC106564287Endonuclease III-like protein 1. (207 aa)
parp2Poly [ADP-ribose] polymerase. (658 aa)
ENSSSAP00000011115annotation not available (847 aa)
ENSSSAP00000005631annotation not available (94 aa)
LOC106591641Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (359 aa)
LOC106588764DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (542 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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