STRINGSTRING
rpa3 rpa3 fan1 fan1 LOC106596053 LOC106596053 ercc8 ercc8 ENSSSAP00000094070 ENSSSAP00000094070 LOC106573817 LOC106573817 LOC106570310 LOC106570310 ddb2 ddb2 LOC106601193 LOC106601193 LOC106601193-2 LOC106601193-2 LOC106584761 LOC106584761 pole pole LOC106604249 LOC106604249 xpc xpc ENSSSAP00000079966 ENSSSAP00000079966 LOC106580482 LOC106580482 polr2i-2 polr2i-2 ENSSSAP00000074515 ENSSSAP00000074515 LOC106606244 LOC106606244 LOC106604510 LOC106604510 usp7 usp7 uvssa uvssa xpa xpa fancc fancc LOC106591641 LOC106591641 LOC106589789 LOC106589789 ENSSSAP00000000810 ENSSSAP00000000810 LOC106588764 LOC106588764 ENSSSAP00000000686 ENSSSAP00000000686 LOC106612201 LOC106612201 LOC106591177 LOC106591177 ercc2 ercc2 LOC106612933 LOC106612933 bivm bivm rfa1 rfa1 RAD23B RAD23B brca2 brca2 DPOD1 DPOD1 ENSSSAP00000045384 ENSSSAP00000045384 gtf2h4 gtf2h4 gtf2h1 gtf2h1 ercc4 ercc4 mnat1 mnat1 syf1 syf1 LOC100196672 LOC100196672 LOC106601920 LOC106601920 sirt1 sirt1 cetn1 cetn1 ENSSSAP00000030774 ENSSSAP00000030774 lig4 lig4 gtf2h5 gtf2h5 ENSSSAP00000019926 ENSSSAP00000019926 LOC106564589 LOC106564589 LOC106607544 LOC106607544 Ercc3 Ercc3 ercc3 ercc3 ercc5 ercc5 ercc1 ercc1 gtf2h3 gtf2h3 ENSSSAP00000104950 ENSSSAP00000104950 ogg1 ogg1 ENSSSAP00000112721 ENSSSAP00000112721 ercc6 ercc6 hus1 hus1 xpa-2 xpa-2 LOC106564287 LOC106564287 ENSSSAP00000012203 ENSSSAP00000012203 pold3 pold3 LOC106613684 LOC106613684 rd23a rd23a LOC106604590 LOC106604590 ENSSSAP00000005631 ENSSSAP00000005631
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpa3Replication protein A3. (159 aa)
fan1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1075 aa)
LOC106596053UV excision repair protein RAD23 homolog A-like. (130 aa)
ercc8DNA excision repair protein ERCC-8 isoform X1. (400 aa)
ENSSSAP00000094070annotation not available (89 aa)
LOC106573817UV excision repair protein RAD23 homolog B-like isoform X1. (468 aa)
LOC106570310Replication protein A 14 kDa subunit-like. (147 aa)
ddb2DNA damage-binding protein 2. (329 aa)
LOC106601193UV excision repair protein RAD23 homolog A-like. (381 aa)
LOC106601193-2UV excision repair protein RAD23 homolog A-like isoform X1. (373 aa)
LOC106584761General transcription factor IIH subunit 1-like. (599 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2292 aa)
LOC106604249Caltractin-like. (159 aa)
xpcDNA repair protein complementing XP-C cells. (905 aa)
ENSSSAP00000079966annotation not available (1325 aa)
LOC106580482DNA polymerase kappa-like. (790 aa)
polr2i-2DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
ENSSSAP00000074515Excision repair cross-complementation group 2. (324 aa)
LOC106606244Ubiquitin carboxyl-terminal hydrolase. (501 aa)
LOC106604510NAD-dependent protein deacetylase sirtuin-1-like isoform X2. (713 aa)
usp7Ubiquitin carboxyl-terminal hydrolase 7. (180 aa)
uvssaUV-stimulated scaffold protein A isoform X1. (749 aa)
xpaDNA-repair protein complementing XP-A cells homolog. (274 aa)
fanccFanconi anemia group C protein isoform X1. (657 aa)
LOC106591641Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (359 aa)
LOC106589789Structure-specific endonuclease subunit SLX4-like isoform X1. (1073 aa)
ENSSSAP00000000810annotation not available (258 aa)
LOC106588764DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (542 aa)
ENSSSAP00000000686MNAT1 component of CDK activating kinase. (303 aa)
LOC106612201Centrin-1-like isoform X2. (219 aa)
LOC106591177Ubiquitin carboxyl-terminal hydrolase 7-like. (289 aa)
ercc2TFIIH basal transcription factor complex helicase subunit. (849 aa)
LOC106612933Replication protein A 70 kDa DNA-binding subunit-like. (632 aa)
bivmBasic immunoglobulin-like variable motif-containing protein isoform X1. (524 aa)
rfa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
RAD23BUV excision repair protein RAD23 homolog B-like isoform X1. (375 aa)
brca2Breast cancer type 2 susceptibility protein isoform X5. (2826 aa)
DPOD1DNA polymerase. (899 aa)
ENSSSAP00000045384Polymerase (RNA) II (DNA directed) polypeptide I. (89 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
gtf2h1General transcription factor IIH subunit 1. (588 aa)
ercc4DNA repair endonuclease XPF. (911 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (314 aa)
syf1Salmo salar Pre-mRNA-splicing factor SYF1 (syf1), mRNA. (896 aa)
LOC100196672General transcription factor IIH subunit. (393 aa)
LOC106601920DNA polymerase delta catalytic subunit-like. (681 aa)
sirt1NAD-dependent protein deacetylase sirtuin-1. (783 aa)
cetn1Centrin-1. (172 aa)
ENSSSAP00000030774annotation not available (144 aa)
lig4DNA ligase. (927 aa)
gtf2h5General transcription factor IIH subunit 5. (71 aa)
ENSSSAP00000019926annotation not available (202 aa)
LOC106564589DNA polymerase lambda-like; Belongs to the DNA polymerase type-X family. (565 aa)
LOC106607544pre-mRNA-splicing factor SYF1-like. (852 aa)
Ercc3ERCC excision repair 3, TFIIH core complex helicase subunit. (100 aa)
ercc3TFIIH basal transcription factor complex helicase XPB subunit. (759 aa)
ercc5DNA repair protein complementing XP-G cells. (775 aa)
ercc1DNA excision repair protein ERCC-1. (383 aa)
gtf2h3General transcription factor IIH subunit 3. (303 aa)
ENSSSAP00000104950Polymerase (DNA directed) kappa. (401 aa)
ogg1N-glycosylase/DNA lyase isoform X1. (440 aa)
ENSSSAP00000112721annotation not available (332 aa)
ercc6DNA excision repair protein ERCC-6. (1488 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (361 aa)
xpa-2DNA repair protein complementing XP-A cells. (278 aa)
LOC106564287Endonuclease III-like protein 1. (207 aa)
ENSSSAP00000012203annotation not available (115 aa)
pold3DNA polymerase delta subunit 3 isoform X1. (449 aa)
LOC106613684UV excision repair protein RAD23 homolog B-like. (478 aa)
rd23aUV excision repair protein RAD23 homolog A. (387 aa)
LOC106604590Caltractin-like. (171 aa)
ENSSSAP00000005631annotation not available (94 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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