STRINGSTRING
LOC106612627 LOC106612627 LOC106588764 LOC106588764 ku70 ku70 LOC106609896 LOC106609896 LOC106563626 LOC106563626 LOC106564589 LOC106564589 LOC106605322 LOC106605322 lig4 lig4 LOC106569276 LOC106569276 rnf8 rnf8 ENSSSAP00000030774 ENSSSAP00000030774 ercc4 ercc4 ENSSSAP00000040693 ENSSSAP00000040693 LOC106580473 LOC106580473 polb polb LOC106562517 LOC106562517 ENSSSAP00000048205 ENSSSAP00000048205 ci142 ci142 LOC106605164 LOC106605164 lig3 lig3 xrcc4 xrcc4 ENSSSAP00000059858 ENSSSAP00000059858 PSDE PSDE MRE11 MRE11 dclre1b dclre1b Mre11 Mre11 LOC106576788 LOC106576788 ENSSSAP00000079966 ENSSSAP00000079966 LOC106582635 LOC106582635 LOC106588429 LOC106588429 LOC106611702 LOC106611702 aplf aplf dclre1a dclre1a LOC106566805 LOC106566805 psde psde LOC106582958 LOC106582958 ercc8 ercc8 prkdc prkdc LOC106603537 LOC106603537 ENSSSAP00000094070 ENSSSAP00000094070 LOC106568159 LOC106568159 LOC106585761 LOC106585761 LOC106572250 LOC106572250 ENSSSAP00000098477 ENSSSAP00000098477 LOC106576644 LOC106576644 ENSSSAP00000101078 ENSSSAP00000101078 LOC106567946 LOC106567946 ercc1 ercc1 LOC106565748 LOC106565748 ENSSSAP00000111484 ENSSSAP00000111484 pola1 pola1 prp19 prp19 ercc6 ercc6 ENSSSAP00000115415 ENSSSAP00000115415 ENSSSAP00000115468 ENSSSAP00000115468 ENSSSAP00000115911 ENSSSAP00000115911 mlh1 mlh1 hmces hmces
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC106612627Bifunctional polynucleotide phosphatase/kinase-like. (619 aa)
LOC106588764DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (542 aa)
ku70ATP-dependent DNA helicase 2 subunit 1 isoform X1. (619 aa)
LOC106609896pre-mRNA-processing factor 19. (505 aa)
LOC106563626Helicase POLQ-like. (1031 aa)
LOC106564589DNA polymerase lambda-like; Belongs to the DNA polymerase type-X family. (565 aa)
LOC106605322DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (510 aa)
lig4DNA ligase. (927 aa)
LOC106569276DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (554 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (538 aa)
ENSSSAP00000030774annotation not available (144 aa)
ercc4DNA repair endonuclease XPF. (911 aa)
ENSSSAP00000040693annotation not available (411 aa)
LOC106580473DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (312 aa)
polbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (344 aa)
LOC106562517Tumor suppressor p53-binding protein 1-like isoform X3. (1923 aa)
ENSSSAP00000048205annotation not available (73 aa)
ci142CI142 protein isoform X1. (214 aa)
LOC106605164DNA repair protein XRCC1-like. (989 aa)
lig3DNA ligase. (1023 aa)
xrcc4DNA repair protein XRCC4 isoform X2. (336 aa)
ENSSSAP00000059858annotation not available (300 aa)
PSDE26S proteasome non-ATPase regulatory subunit 14. (350 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (474 aa)
dclre1b5' exonuclease Apollo isoform X1. (704 aa)
Mre11MRE11 homolog, double strand break repair nuclease. (452 aa)
LOC106576788DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (511 aa)
ENSSSAP00000079966annotation not available (1325 aa)
LOC106582635DNA repair protein XRCC1-like. (633 aa)
LOC106588429Intermediate filament family orphan 1-like isoform X2; Belongs to the intermediate filament family. (638 aa)
LOC106611702pre-mRNA-processing factor 19-like. (505 aa)
aplfAprataxin and PNK-like factor isoform X1. (356 aa)
dclre1aDNA cross-link repair 1A protein. (898 aa)
LOC106566805Intermediate filament family orphan 2-like isoform X1; Belongs to the intermediate filament family. (528 aa)
psde26S proteasome non-ATPase regulatory subunit 14. (353 aa)
LOC106582958Intermediate filament family orphan 2-like isoform X2; Belongs to the intermediate filament family. (512 aa)
ercc8DNA excision repair protein ERCC-8 isoform X1. (400 aa)
prkdcDNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3937 aa)
LOC106603537UV radiation resistance-associated gene protein-like. (755 aa)
ENSSSAP00000094070annotation not available (89 aa)
LOC106568159LOW QUALITY PROTEIN: helicase POLQ-like. (904 aa)
LOC106585761DNA repair protein XRCC4-like isoform X1. (317 aa)
LOC106572250Intermediate filament family orphan 2-like isoform X2; Belongs to the intermediate filament family. (532 aa)
ENSSSAP00000098477Intermediate filament family orphan 1a. (589 aa)
LOC106576644Intermediate filament family orphan 1-like isoform X1; Belongs to the intermediate filament family. (653 aa)
ENSSSAP00000101078annotation not available (498 aa)
LOC106567946UV radiation resistance-associated gene protein-like isoform X1. (733 aa)
ercc1DNA excision repair protein ERCC-1. (383 aa)
LOC106565748Histone-lysine N-methyltransferase SETMAR-like. (304 aa)
ENSSSAP00000111484SET domain and mariner transposase fusion gene. (283 aa)
pola1DNA polymerase. (1466 aa)
prp19Pre-mRNA-processing factor 19. (505 aa)
ercc6DNA excision repair protein ERCC-6. (1488 aa)
ENSSSAP00000115415annotation not available (257 aa)
ENSSSAP00000115468X-ray repair complementing defective repair in Chinese hamster cells 6. (364 aa)
ENSSSAP00000115911annotation not available (260 aa)
mlh1DNA mismatch repair protein Mlh1. (729 aa)
hmcesAbasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (363 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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