30 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100380693	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1096 aa)
	LOC106581179	Glyoxalase domain-containing protein 4-like. (297 aa)
	msh6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1386 aa)
	ENSSSAP00000039593	annotation not available (118 aa)
	LOC106612699	Forkhead box protein A2-like. (443 aa)
	LOC106564609	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (225 aa)
	LOC106604847	Insulin-degrading enzyme-like isoform X2; Belongs to the peptidase M16 family. (1020 aa)
	LOC106563167	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (468 aa)
	ENSSSAP00000017343	Leptin a. (175 aa)
	lrrk2	Leucine-rich repeat serine/threonine-protein kinase 2 isoform X2. (2564 aa)
	coq7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (225 aa)
	ENSSSAP00000013429	annotation not available (197 aa)
	ENSSSAP00000012100	Major facilitator superfamily domain containing 6-like. (504 aa)
	face1	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (513 aa)
	sirt6	NAD-dependent protein deacetylase sirtuin-6 isoform X1. (383 aa)
	ENSSSAP00000114968	annotation not available (273 aa)
	LOC106611774	Malate synthase-like isoform X1. (1074 aa)
	ENSSSAP00000105257	Serine-protein kinase ATM-like. (111 aa)
	ENSSSAP00000101954	annotation not available (48 aa)
	LOC106611674	Selenoprotein H-like. (111 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (928 aa)
	LOC106601377	Major facilitator superfamily domain-containing protein 6-like. (594 aa)
	ENSSSAP00000086389	annotation not available (132 aa)
	fkh	Fork head domain protein isoform X1. (435 aa)
	LOC106576795	Insulin-degrading enzyme isoform X2; Belongs to the peptidase M16 family. (1018 aa)
	ENSSSAP00000058852	annotation not available (126 aa)
	LOC106560606	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1-like isoform X1. (942 aa)
	LOC106612786	Glyoxalase domain-containing protein 4-like. (414 aa)
	LOC106561227	Uncharacterized protein LOC106561227. (171 aa)
	atm	Non-specific serine/threonine protein kinase. (3172 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSSAP00000105257	ENSSSAP00000114968	ENSSSAP00000105257	ENSSSAP00000114968	Serine-protein kinase ATM-like.	annotation not available	0.412
ENSSSAP00000105257	msh2	ENSSSAP00000105257	ENSSSAP00000099762	Serine-protein kinase ATM-like.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.748
ENSSSAP00000105257	msh6	ENSSSAP00000105257	ENSSSAP00000040921	Serine-protein kinase ATM-like.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.735
ENSSSAP00000105257	sirt6	ENSSSAP00000105257	ENSSSAP00000118458	Serine-protein kinase ATM-like.	NAD-dependent protein deacetylase sirtuin-6 isoform X1.	0.412
ENSSSAP00000114968	ENSSSAP00000105257	ENSSSAP00000114968	ENSSSAP00000105257	annotation not available	Serine-protein kinase ATM-like.	0.412
ENSSSAP00000114968	atm	ENSSSAP00000114968	ENSSSAP00000045237	annotation not available	Non-specific serine/threonine protein kinase.	0.412
LOC106563167	LOC106576795	ENSSSAP00000018802	ENSSSAP00000062272	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Insulin-degrading enzyme isoform X2; Belongs to the peptidase M16 family.	0.463
LOC106563167	LOC106604847	ENSSSAP00000018802	ENSSSAP00000022356	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Insulin-degrading enzyme-like isoform X2; Belongs to the peptidase M16 family.	0.459
LOC106564609	coq7	ENSSSAP00000026792	ENSSSAP00000014290	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner.	0.900
LOC106576795	LOC106563167	ENSSSAP00000062272	ENSSSAP00000018802	Insulin-degrading enzyme isoform X2; Belongs to the peptidase M16 family.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.463
LOC106576795	face1	ENSSSAP00000062272	ENSSSAP00000006571	Insulin-degrading enzyme isoform X2; Belongs to the peptidase M16 family.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.459
LOC106604847	LOC106563167	ENSSSAP00000022356	ENSSSAP00000018802	Insulin-degrading enzyme-like isoform X2; Belongs to the peptidase M16 family.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.459
LOC106604847	face1	ENSSSAP00000022356	ENSSSAP00000006571	Insulin-degrading enzyme-like isoform X2; Belongs to the peptidase M16 family.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.459
atm	ENSSSAP00000114968	ENSSSAP00000045237	ENSSSAP00000114968	Non-specific serine/threonine protein kinase.	annotation not available	0.412
atm	msh2	ENSSSAP00000045237	ENSSSAP00000099762	Non-specific serine/threonine protein kinase.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.748
atm	msh6	ENSSSAP00000045237	ENSSSAP00000040921	Non-specific serine/threonine protein kinase.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.736
atm	sirt6	ENSSSAP00000045237	ENSSSAP00000118458	Non-specific serine/threonine protein kinase.	NAD-dependent protein deacetylase sirtuin-6 isoform X1.	0.412
coq7	LOC106564609	ENSSSAP00000014290	ENSSSAP00000026792	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner.	0.900
face1	LOC106576795	ENSSSAP00000006571	ENSSSAP00000062272	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Insulin-degrading enzyme isoform X2; Belongs to the peptidase M16 family.	0.459
face1	LOC106604847	ENSSSAP00000006571	ENSSSAP00000022356	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Insulin-degrading enzyme-like isoform X2; Belongs to the peptidase M16 family.	0.459