24 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100380636	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (953 aa)
	aptx	Aprataxin. (348 aa)
	cpsf3	Cleavage and polyadenylation specificity factor subunit 3. (692 aa)
	fan1	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1075 aa)
	LOC106571262	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (959 aa)
	dclre1a	DNA cross-link repair 1A protein. (898 aa)
	dcp2	m7GpppN-mRNA hydrolase isoform X1. (402 aa)
	pld3	Phospholipase D family member 3. (495 aa)
	LOC106601332	Uncharacterized protein C19orf43-like. (168 aa)
	Mre11	MRE11 homolog, double strand break repair nuclease. (452 aa)
	LOC106599575	5'-3' exoribonuclease 1. (1698 aa)
	dclre1b	5' exonuclease Apollo isoform X1. (704 aa)
	MRE11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (474 aa)
	LOC106612271	Uncharacterized protein LOC106612271 isoform X1. (868 aa)
	exo5	Exonuclease V. (322 aa)
	LOC106612700	Phospholipase D3-like. (504 aa)
	LOC106606733	Decapping and exoribonuclease protein-like. (439 aa)
	TRIR	Telomerase RNA component interacting RNase. (99 aa)
	ENSSSAP00000028050	Telomerase RNA component interacting RNase. (101 aa)
	DXO	Decapping and exoribonuclease protein-like. (439 aa)
	PLD4	Phospholipase D4-like. (519 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (402 aa)
	LOC106568870	5'-3' exoribonuclease 1. (1695 aa)
	exo1	Exonuclease 1. (786 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DXO	LOC100380636	ENSSSAP00000008307	ENSSSAP00000105185	Decapping and exoribonuclease protein-like.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.963
DXO	LOC106568870	ENSSSAP00000008307	ENSSSAP00000105643	Decapping and exoribonuclease protein-like.	5'-3' exoribonuclease 1.	0.595
DXO	LOC106571262	ENSSSAP00000008307	ENSSSAP00000088392	Decapping and exoribonuclease protein-like.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.963
DXO	LOC106599575	ENSSSAP00000008307	ENSSSAP00000072262	Decapping and exoribonuclease protein-like.	5'-3' exoribonuclease 1.	0.595
DXO	dcp2	ENSSSAP00000008307	ENSSSAP00000086332	Decapping and exoribonuclease protein-like.	m7GpppN-mRNA hydrolase isoform X1.	0.601
DXO	exo1	ENSSSAP00000008307	ENSSSAP00000105207	Decapping and exoribonuclease protein-like.	Exonuclease 1.	0.519
FEN1	MRE11	ENSSSAP00000112685	ENSSSAP00000067517	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.992
FEN1	Mre11	ENSSSAP00000112685	ENSSSAP00000074445	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	MRE11 homolog, double strand break repair nuclease.	0.992
FEN1	aptx	ENSSSAP00000112685	ENSSSAP00000105070	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Aprataxin.	0.628
FEN1	cpsf3	ENSSSAP00000112685	ENSSSAP00000096441	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Cleavage and polyadenylation specificity factor subunit 3.	0.417
FEN1	dclre1a	ENSSSAP00000112685	ENSSSAP00000086774	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA cross-link repair 1A protein.	0.681
FEN1	dclre1b	ENSSSAP00000112685	ENSSSAP00000068491	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	5' exonuclease Apollo isoform X1.	0.681
FEN1	exo1	ENSSSAP00000112685	ENSSSAP00000105207	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Exonuclease 1.	0.972
LOC100380636	DXO	ENSSSAP00000105185	ENSSSAP00000008307	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	Decapping and exoribonuclease protein-like.	0.963
LOC100380636	LOC106568870	ENSSSAP00000105185	ENSSSAP00000105643	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	5'-3' exoribonuclease 1.	0.885
LOC100380636	LOC106599575	ENSSSAP00000105185	ENSSSAP00000072262	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	5'-3' exoribonuclease 1.	0.885
LOC100380636	LOC106606733	ENSSSAP00000105185	ENSSSAP00000037168	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	Decapping and exoribonuclease protein-like.	0.963
LOC100380636	cpsf3	ENSSSAP00000105185	ENSSSAP00000096441	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	Cleavage and polyadenylation specificity factor subunit 3.	0.655
LOC100380636	dcp2	ENSSSAP00000105185	ENSSSAP00000086332	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	m7GpppN-mRNA hydrolase isoform X1.	0.601
LOC100380636	exo1	ENSSSAP00000105185	ENSSSAP00000105207	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	Exonuclease 1.	0.401