STRINGSTRING
rfa1 rfa1 telo2 telo2 rad51 rad51 pot1 pot1 PTGES3 PTGES3 ENSSSAP00000027424 ENSSSAP00000027424 LOC106564697 LOC106564697 ENSSSAP00000019926 ENSSSAP00000019926 LOC106608819 LOC106608819 LOC106607888 LOC106607888 zbtb48 zbtb48 LOC106608971 LOC106608971 LOC106567008 LOC106567008 LOC106566721 LOC106566721 LOC106571940 LOC106571940 WRAP53 WRAP53 nola2 nola2 LOC106563393 LOC106563393 LOC106603897 LOC106603897 DKC1 DKC1 LOC106586766 LOC106586766 LOC106572567 LOC106572567 rad50 rad50 LOC106604513 LOC106604513 gar1 gar1 LOC106577940 LOC106577940 LOC106612933 LOC106612933 tert tert
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rfa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
telo2Telomere length regulation protein TEL2 homolog isoform X1. (847 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa)
pot1Protection of telomeres protein 1 isoform X1. (838 aa)
PTGES3Prostaglandin E synthase 3-like isoform X1. (233 aa)
ENSSSAP00000027424annotation not available (95 aa)
LOC106564697CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (375 aa)
ENSSSAP00000019926annotation not available (202 aa)
LOC106608819Telomerase Cajal body protein 1-like. (555 aa)
LOC106607888DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
zbtb48Zinc finger and BTB domain-containing protein 48. (842 aa)
LOC106608971H/ACA ribonucleoprotein complex subunit 3 isoform X2. (64 aa)
LOC106567008Prostaglandin E synthase 3-like. (217 aa)
LOC106566721Prostaglandin E synthase 3-like. (192 aa)
LOC106571940Prostaglandin E synthase 3-like isoform X1. (160 aa)
WRAP53Telomerase Cajal body protein 1-like. (731 aa)
nola2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (155 aa)
LOC106563393H/ACA ribonucleoprotein complex subunit 4-like. (500 aa)
LOC106603897Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (156 aa)
DKC1H/ACA ribonucleoprotein complex subunit 4. (534 aa)
LOC106586766CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (439 aa)
LOC106572567Zinc finger and BTB domain-containing protein 48-like isoform X1. (823 aa)
rad50DNA repair protein RAD50. (1316 aa)
LOC106604513H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (241 aa)
gar1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (209 aa)
LOC106577940H/ACA ribonucleoprotein complex subunit 3-like. (64 aa)
LOC106612933Replication protein A 70 kDa DNA-binding subunit-like. (632 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1151 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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