(11 nodes) Intestinal cholesterol absorption network (Salmo salar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CEL-2	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (593 aa)
	LOC106600427	Niemann-Pick C1 protein-like. (1356 aa)
	ENSSSAP00000051691	Niemann-Pick C1 protein-like. (103 aa)
	ENSSSAP00000065828	annotation not available (122 aa)
	CEL	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (570 aa)
	LIMA1	LIM domain and actin-binding protein 1. (710 aa)
	LOC106565453	LIM domain and actin-binding protein 1-like isoform X1. (732 aa)
	LOC106569313	Niemann-Pick C1 protein-like. (1281 aa)
	NPC1L1	Niemann-Pick C1-like protein 1. (1349 aa)
	LOC106567074	LIM domain and actin-binding protein 1-like isoform X1. (714 aa)
	LOC106583291	LIM domain and actin-binding protein 1-like isoform X1. (723 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEL	CEL-2	ENSSSAP00000070127	ENSSSAP00000072924	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.901
CEL	NPC1L1	ENSSSAP00000070127	ENSSSAP00000085874	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Niemann-Pick C1-like protein 1.	0.535
CEL-2	CEL	ENSSSAP00000072924	ENSSSAP00000070127	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.901
ENSSSAP00000051691	LOC106569313	ENSSSAP00000051691	ENSSSAP00000082061	Niemann-Pick C1 protein-like.	Niemann-Pick C1 protein-like.	0.900
LOC106569313	ENSSSAP00000051691	ENSSSAP00000082061	ENSSSAP00000051691	Niemann-Pick C1 protein-like.	Niemann-Pick C1 protein-like.	0.900
NPC1L1	CEL	ENSSSAP00000085874	ENSSSAP00000070127	Niemann-Pick C1-like protein 1.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.535