42 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106591430	Ell-associated factor Eaf-like; Belongs to the PDGF/VEGF growth factor family. (674 aa)
	LOC100136559	Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
	LOC106565196	Protein phosphatase 1 regulatory subunit 3C-B-like. (306 aa)
	LOC106607441	Uncharacterized protein LOC106607441; Belongs to the PDGF/VEGF growth factor family. (543 aa)
	LOC106580423	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1668 aa)
	LOC106607927	Protein phosphatase 1 regulatory subunit. (324 aa)
	LOC106563715	Protein phosphatase 1 regulatory subunit. (305 aa)
	ENSSSAP00000027775	annotation not available (82 aa)
	ENSSSAP00000027793	annotation not available (248 aa)
	LOC106585059	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1683 aa)
	LOC106609475	Insulin-like growth factor I isoform X1. (211 aa)
	LOC106573651	Sphingomyelin phosphodiesterase 3-like. (665 aa)
	LOC106600896	Trichohyalin-like; Belongs to the PDGF/VEGF growth factor family. (543 aa)
	ENSSSAP00000050057	annotation not available (274 aa)
	LOC100136550	Insulin-like growth factor II. (214 aa)
	LOC106578980	Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (320 aa)
	LOC106581108	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1686 aa)
	LOC100136517	Insulin-like growth factor I isoform X1. (198 aa)
	LOC106562302	Protein phosphatase 1 regulatory subunit 3E-like. (314 aa)
	LOC106613337	Transforming growth factor beta; Belongs to the TGF-beta family. (384 aa)
	LOC106578584	Protein phosphatase 1 regulatory subunit 3G-like. (311 aa)
	ENSSSAP00000065329	Platelet-derived growth factor subunit B. (146 aa)
	ENSSSAP00000066423	Parathyroid hormone 1a. (113 aa)
	LOC106590089	Protein phosphatase 1 regulatory subunit 3G-like. (260 aa)
	ENSSSAP00000071012	Parathyroid hormone 1a. (110 aa)
	ENSSSAP00000075546	annotation not available (529 aa)
	LOC106612978	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1737 aa)
	pask	PAS domain-containing serine/threonine-protein kinase isoform X2. (1239 aa)
	PPP1R3D	Protein phosphatase 1 regulatory subunit 3D-like. (374 aa)
	LOC106589379	Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (320 aa)
	LOC106572379	Uncharacterized protein LOC106572379 isoform X1. (941 aa)
	ENSSSAP00000083370	Protein phosphatase 1, regulatory subunit 3Db. (244 aa)
	LOC106567969	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1684 aa)
	ppp1r3b	Protein phosphatase 1 regulatory subunit. (289 aa)
	LOC106583920	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (986 aa)
	LOC106577132	Protein phosphatase 1 regulatory subunit. (329 aa)
	LOC106560916	Sphingomyelin phosphodiesterase 3-like. (673 aa)
	LOC106572067	Protein phosphatase 1 regulatory subunit 3D-like. (302 aa)
	LOC106563826	General transcription factor II-I repeat domain-containing protein 2-like. (603 aa)
	LOC106600693	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (986 aa)
	LOC106603518	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1687 aa)
	LOC106563563	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSSAP00000027775	LOC106583920	ENSSSAP00000027775	ENSSSAP00000093551	annotation not available	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.838
ENSSSAP00000027775	LOC106600693	ENSSSAP00000027775	ENSSSAP00000002223	annotation not available	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.838
ENSSSAP00000065329	LOC106591430	ENSSSAP00000065329	ENSSSAP00000003899	Platelet-derived growth factor subunit B.	Ell-associated factor Eaf-like; Belongs to the PDGF/VEGF growth factor family.	0.900
ENSSSAP00000066423	LOC100136517	ENSSSAP00000066423	ENSSSAP00000052543	Parathyroid hormone 1a.	Insulin-like growth factor I isoform X1.	0.512
ENSSSAP00000066423	LOC100136550	ENSSSAP00000066423	ENSSSAP00000051358	Parathyroid hormone 1a.	Insulin-like growth factor II.	0.447
ENSSSAP00000066423	LOC106609475	ENSSSAP00000066423	ENSSSAP00000040530	Parathyroid hormone 1a.	Insulin-like growth factor I isoform X1.	0.512
ENSSSAP00000071012	LOC100136517	ENSSSAP00000071012	ENSSSAP00000052543	Parathyroid hormone 1a.	Insulin-like growth factor I isoform X1.	0.512
ENSSSAP00000071012	LOC100136550	ENSSSAP00000071012	ENSSSAP00000051358	Parathyroid hormone 1a.	Insulin-like growth factor II.	0.447
ENSSSAP00000071012	LOC106609475	ENSSSAP00000071012	ENSSSAP00000040530	Parathyroid hormone 1a.	Insulin-like growth factor I isoform X1.	0.512
LOC100136517	ENSSSAP00000066423	ENSSSAP00000052543	ENSSSAP00000066423	Insulin-like growth factor I isoform X1.	Parathyroid hormone 1a.	0.512
LOC100136517	ENSSSAP00000071012	ENSSSAP00000052543	ENSSSAP00000071012	Insulin-like growth factor I isoform X1.	Parathyroid hormone 1a.	0.512
LOC100136517	LOC100136550	ENSSSAP00000052543	ENSSSAP00000051358	Insulin-like growth factor I isoform X1.	Insulin-like growth factor II.	0.744
LOC100136517	LOC100136559	ENSSSAP00000052543	ENSSSAP00000004983	Insulin-like growth factor I isoform X1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.511
LOC100136517	LOC106563563	ENSSSAP00000052543	ENSSSAP00000109831	Insulin-like growth factor I isoform X1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.511
LOC100136517	LOC106613337	ENSSSAP00000052543	ENSSSAP00000053777	Insulin-like growth factor I isoform X1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.511
LOC100136550	ENSSSAP00000066423	ENSSSAP00000051358	ENSSSAP00000066423	Insulin-like growth factor II.	Parathyroid hormone 1a.	0.447
LOC100136550	ENSSSAP00000071012	ENSSSAP00000051358	ENSSSAP00000071012	Insulin-like growth factor II.	Parathyroid hormone 1a.	0.447
LOC100136550	LOC100136517	ENSSSAP00000051358	ENSSSAP00000052543	Insulin-like growth factor II.	Insulin-like growth factor I isoform X1.	0.744
LOC100136550	LOC106609475	ENSSSAP00000051358	ENSSSAP00000040530	Insulin-like growth factor II.	Insulin-like growth factor I isoform X1.	0.777
LOC100136559	LOC100136517	ENSSSAP00000004983	ENSSSAP00000052543	Transforming growth factor beta; Belongs to the TGF-beta family.	Insulin-like growth factor I isoform X1.	0.511