68 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bmp1	Metalloendopeptidase. (965 aa)
	LOC106613997	Hematopoietically-expressed homeobox protein hhex-like. (286 aa)
	ENSSSAP00000000384	annotation not available (35 aa)
	ENSSSAP00000000399	annotation not available (246 aa)
	CCDC134	Coiled-coil domain-containing protein 134-like isoform X2. (227 aa)
	LOC106577459	Ethanolamine-phosphate phospho-lyase-like; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (511 aa)
	LOC106606709	Protein kinase C alpha type-like. (127 aa)
	LOC106606719	Protein kinase C alpha type-like; Belongs to the protein kinase superfamily. (476 aa)
	trim33	E3 ubiquitin-protein ligase TRIM33 isoform X2. (1207 aa)
	LOC106581161	T-box transcription factor TBX20-like isoform X3. (441 aa)
	LOC106574039	T-cell acute lymphocytic leukemia protein 1 homolog. (357 aa)
	LOC106613058	Chordin-like. (956 aa)
	slc25a37	Mitoferrin-1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (337 aa)
	LOC106566845	E3 ubiquitin-protein ligase TRIM33-like isoform X3. (1307 aa)
	med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1794 aa)
	slc40a1	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (577 aa)
	lclat1	Lysocardiolipin acyltransferase 1. (383 aa)
	lmo2	Rhombotin-2. (159 aa)
	LOC100136364	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1542 aa)
	LOC106592127	Protein kinase C alpha type-like. (308 aa)
	LOC106586140	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (573 aa)
	LOC106613407	Transcriptional coactivator YAP1-like. (328 aa)
	ENSSSAP00000031475	annotation not available (79 aa)
	LOC106591110	Cyclic AMP-dependent transcription factor ATF-4-like. (436 aa)
	CXA1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (360 aa)
	LOC106568924	T-cell acute lymphocytic leukemia protein 1-like isoform X2. (351 aa)
	LOC106595901	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (243 aa)
	LOC106579720	Nuclear receptor coactivator 2-like. (1288 aa)
	TBX20	T-box transcription factor TBX20 isoform X3. (441 aa)
	LOC106585578	Mitoferrin-1-like isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (324 aa)
	LOC100286425	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (506 aa)
	LOC106577940	H/ACA ribonucleoprotein complex subunit 3-like. (64 aa)
	LOC106594733	Non-specific serine/threonine protein kinase. (273 aa)
	LOC106594070	Protein kinase C alpha type-like. (185 aa)
	LOC106586454	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (646 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
	LOC106581582	Transcriptional coactivator YAP1-like. (151 aa)
	NCOA2	Nuclear receptor coactivator 2-like. (1537 aa)
	LOC106579847	Metalloendopeptidase. (979 aa)
	LOC106581290	Chordin; Belongs to the chordin family. (947 aa)
	alas2	5-aminolevulinate synthase. (601 aa)
	cc134	Coiled-coil domain-containing protein 134 isoform X2. (271 aa)
	LOC100136366	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1523 aa)
	LOC106585852	SH2B adapter protein 3-like. (651 aa)
	tgfr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (549 aa)
	LOC106578384	Polycomb complex protein BMI-1-A-like. (329 aa)
	ENSSSAP00000020244	annotation not available (65 aa)
	LOC106564394	Cyclic AMP-dependent transcription factor ATF-4-like. (462 aa)
	myct1	Myc target protein 1. (225 aa)
	ENSSSAP00000018633	annotation not available (35 aa)
	gata1	GATA-binding factor 1. (424 aa)
	kpca	Protein kinase C beta type-like. (677 aa)
	LOC106611107	Lysocardiolipin acyltransferase 1-like. (337 aa)
	LOC106595161	Histone deacetylase 9-B-like. (480 aa)
	hhex	Hematopoietically-expressed Homeobox protein hhex. (280 aa)
	LOC106599084	T-cell acute lymphocytic leukemia protein 1-like isoform X2. (352 aa)
	LOC106606173	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (582 aa)
	LOC106608971	H/ACA ribonucleoprotein complex subunit 3 isoform X2. (64 aa)
	ism1	Isthmin-1. (482 aa)
	tal1	T-cell acute lymphocytic leukemia protein 1 homolog. (353 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (571 aa)
	LOC106580188	SH2B adapter protein 3-like. (653 aa)
	NCOA2-2	Nuclear receptor coactivator 2-like isoform X1. (1550 aa)
	LOC106582882	GATA-binding factor 2-like isoform X2. (425 aa)
	GJA1	Gap junction protein alpha 1. (278 aa)
	ENSSSAP00000118178	Isthmin-1-like. (164 aa)
	LOC106585594	Metalloendopeptidase. (984 aa)
	bmi1a	Polycomb complex protein BMI-1-A isoform X1. (363 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100136364	LOC100136366	ENSSSAP00000053223	ENSSSAP00000088231	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.900
LOC100136364	LOC106595161	ENSSSAP00000053223	ENSSSAP00000010527	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Histone deacetylase 9-B-like.	0.440
LOC100136366	LOC100136364	ENSSSAP00000088231	ENSSSAP00000053223	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.900
LOC100136366	LOC106595161	ENSSSAP00000088231	ENSSSAP00000010527	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Histone deacetylase 9-B-like.	0.440
LOC106566845	LOC106582882	ENSSSAP00000042245	ENSSSAP00000120071	E3 ubiquitin-protein ligase TRIM33-like isoform X3.	GATA-binding factor 2-like isoform X2.	0.425
LOC106566845	gata1	ENSSSAP00000042245	ENSSSAP00000017901	E3 ubiquitin-protein ligase TRIM33-like isoform X3.	GATA-binding factor 1.	0.425
LOC106568924	LOC106582882	ENSSSAP00000030149	ENSSSAP00000120071	T-cell acute lymphocytic leukemia protein 1-like isoform X2.	GATA-binding factor 2-like isoform X2.	0.836
LOC106568924	gata1	ENSSSAP00000030149	ENSSSAP00000017901	T-cell acute lymphocytic leukemia protein 1-like isoform X2.	GATA-binding factor 1.	0.836
LOC106568924	lmo2	ENSSSAP00000030149	ENSSSAP00000053005	T-cell acute lymphocytic leukemia protein 1-like isoform X2.	Rhombotin-2.	0.986
LOC106574039	LOC106582882	ENSSSAP00000039817	ENSSSAP00000120071	T-cell acute lymphocytic leukemia protein 1 homolog.	GATA-binding factor 2-like isoform X2.	0.836
LOC106574039	gata1	ENSSSAP00000039817	ENSSSAP00000017901	T-cell acute lymphocytic leukemia protein 1 homolog.	GATA-binding factor 1.	0.875
LOC106574039	lmo2	ENSSSAP00000039817	ENSSSAP00000053005	T-cell acute lymphocytic leukemia protein 1 homolog.	Rhombotin-2.	0.988
LOC106574039	slc25a37	ENSSSAP00000039817	ENSSSAP00000041476	T-cell acute lymphocytic leukemia protein 1 homolog.	Mitoferrin-1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.410
LOC106577940	LOC106608971	ENSSSAP00000067534	ENSSSAP00000093142	H/ACA ribonucleoprotein complex subunit 3-like.	H/ACA ribonucleoprotein complex subunit 3 isoform X2.	0.901
LOC106579720	med1	ENSSSAP00000024394	ENSSSAP00000044565	Nuclear receptor coactivator 2-like.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.743
LOC106579847	LOC106581290	ENSSSAP00000081523	ENSSSAP00000081696	Metalloendopeptidase.	Chordin; Belongs to the chordin family.	0.817
LOC106579847	LOC106581582	ENSSSAP00000081523	ENSSSAP00000074320	Metalloendopeptidase.	Transcriptional coactivator YAP1-like.	0.459
LOC106579847	LOC106613058	ENSSSAP00000081523	ENSSSAP00000040636	Metalloendopeptidase.	Chordin-like.	0.817
LOC106579847	LOC106613407	ENSSSAP00000081523	ENSSSAP00000055924	Metalloendopeptidase.	Transcriptional coactivator YAP1-like.	0.459
LOC106581290	LOC106579847	ENSSSAP00000081696	ENSSSAP00000081523	Chordin; Belongs to the chordin family.	Metalloendopeptidase.	0.817