STRINGSTRING
LOC106564589 LOC106564589 ENSSSAP00000041843 ENSSSAP00000041843 LOC106585927 LOC106585927 LOC106588764 LOC106588764 arpc3 arpc3 LOC106591833 LOC106591833 LOC106612941 LOC106612941 wdr70 wdr70 LOC106569430 LOC106569430 LOC106607888 LOC106607888 LOC106609896 LOC106609896 tonsl tonsl LOC106608819 LOC106608819 LOC106564263 LOC106564263 LOC106562128 LOC106562128 LOC106580170 LOC106580170 slf1 slf1 ENSSSAP00000017829 ENSSSAP00000017829 LOC106583181 LOC106583181 ENSSSAP00000021451 ENSSSAP00000021451 ENSSSAP00000022117 ENSSSAP00000022117 ENSSSAP00000026825 ENSSSAP00000026825 ENSSSAP00000030199 ENSSSAP00000030199 ENSSSAP00000041823 ENSSSAP00000041823 Parp3 Parp3 LOC106565555 LOC106565555 LOC106612627 LOC106612627 LOC106571917 LOC106571917 rnf8 rnf8 rad51 rad51 LOC106608890 LOC106608890 ENSSSAP00000043807 ENSSSAP00000043807 ENSSSAP00000045307 ENSSSAP00000045307 ENSSSAP00000045345 ENSSSAP00000045345 LOC106563201 LOC106563201 NABP2 NABP2 LOC106562517 LOC106562517 ENSSSAP00000048205 ENSSSAP00000048205 parp1 parp1 LOC106583347 LOC106583347 ci142 ci142 LOC106577860 LOC106577860 LOC106607723 LOC106607723 xrcc4 xrcc4 ACTR3 ACTR3 ENSSSAP00000059858 ENSSSAP00000059858 LOC106574678 LOC106574678 LOC106581699 LOC106581699 ENSSSAP00000065800 ENSSSAP00000065800 ENSSSAP00000066677 ENSSSAP00000066677 MRE11 MRE11 ENSSSAP00000068802 ENSSSAP00000068802 ACTR3-2 ACTR3-2 Mre11 Mre11 timeless timeless LOC106561926 LOC106561926 WRAP53 WRAP53 LOC106562928 LOC106562928 LOC106574434 LOC106574434 LOC106580289 LOC106580289 LOC106571328 LOC106571328 LOC106564849 LOC106564849 LOC106586392 LOC106586392 LOC106583204 LOC106583204 LOC106611702 LOC106611702 ENSSSAP00000085304 ENSSSAP00000085304 fam35a fam35a aplf aplf rpa3 rpa3 LOC106613810 LOC106613810 LOC106590210 LOC106590210 LOC106580664 LOC106580664 LOC106570310 LOC106570310 ddb1 ddb1 LOC106585012 LOC106585012 ENSSSAP00000101078 ENSSSAP00000101078 LOC106580672 LOC106580672 ENSSSAP00000101867 ENSSSAP00000101867 rad50 rad50 smchd1 smchd1 LOC106589757 LOC106589757 smarcad1 smarcad1 LOC106575630 LOC106575630 samhd1 samhd1 LOC106565748 LOC106565748 polh polh ENSSSAP00000111484 ENSSSAP00000111484 prp19 prp19 ENSSSAP00000114968 ENSSSAP00000114968 LOC106565815 LOC106565815 LOC106590428 LOC106590428 hus1 hus1 rnf138 rnf138 LOC106582342 LOC106582342 sirt6 sirt6 rad18 rad18 LOC106565577 LOC106565577 LOC106563156 LOC106563156
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC106564589DNA polymerase lambda-like; Belongs to the DNA polymerase type-X family. (565 aa)
ENSSSAP00000041843annotation not available (108 aa)
LOC106585927Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (398 aa)
LOC106588764DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (542 aa)
arpc3Salmo salar actin related protein 2/3 complex, subunit 3 (arpc3), mRNA. (185 aa)
LOC106591833NAD-dependent protein deacetylase sirtuin-7-like isoform X1. (406 aa)
LOC106612941Uncharacterized protein LOC106612941. (1533 aa)
wdr70WD repeat-containing protein 70. (653 aa)
LOC106569430Transitional endoplasmic reticulum ATPase-like; Belongs to the AAA ATPase family. (817 aa)
LOC106607888DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
LOC106609896pre-mRNA-processing factor 19. (505 aa)
tonslTonsoku-like protein. (1433 aa)
LOC106608819Telomerase Cajal body protein 1-like. (555 aa)
LOC106564263Transitional endoplasmic reticulum ATPase-like; Belongs to the AAA ATPase family. (569 aa)
LOC106562128Meiotic recombination protein REC114-like. (231 aa)
LOC106580170annotation not available (1017 aa)
slf1Ankyrin repeat domain-containing protein 32 isoform X1. (896 aa)
ENSSSAP00000017829annotation not available (191 aa)
LOC106583181E3 ubiquitin-protein ligase RAD18-like isoform X1. (584 aa)
ENSSSAP00000021451annotation not available (86 aa)
ENSSSAP00000022117annotation not available (86 aa)
ENSSSAP00000026825annotation not available (119 aa)
ENSSSAP00000030199annotation not available (162 aa)
ENSSSAP00000041823Ring finger protein 169. (501 aa)
Parp3Poly (ADP-ribose) polymerase family, member 3. (310 aa)
LOC106565555Actin-related protein 2/3 complex subunit 4. (234 aa)
LOC106612627Bifunctional polynucleotide phosphatase/kinase-like. (619 aa)
LOC106571917NAD-dependent protein deacetylase sirtuin-7-like isoform X2. (406 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (538 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa)
LOC106608890Actin-related protein 2-like; Belongs to the actin family. (394 aa)
ENSSSAP00000043807annotation not available (153 aa)
ENSSSAP00000045307annotation not available (86 aa)
ENSSSAP00000045345annotation not available (48 aa)
LOC106563201annotation not available (946 aa)
NABP2SOSS complex subunit B1-B-like isoform X1. (199 aa)
LOC106562517Tumor suppressor p53-binding protein 1-like isoform X3. (1923 aa)
ENSSSAP00000048205annotation not available (73 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1030 aa)
LOC106583347SOSS complex subunit B1-like. (193 aa)
ci142CI142 protein isoform X1. (214 aa)
LOC106577860Actin-related protein 2-like; Belongs to the actin family. (394 aa)
LOC106607723E3 UFM1-protein ligase 1-like. (794 aa)
xrcc4DNA repair protein XRCC4 isoform X2. (336 aa)
ACTR3Actin-related protein 3 isoform X2; Belongs to the actin family. (437 aa)
ENSSSAP00000059858annotation not available (300 aa)
LOC106574678Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (359 aa)
LOC106581699Actin-related protein 3-like; Belongs to the actin family. (444 aa)
ENSSSAP00000065800Zgc:101664. (201 aa)
ENSSSAP00000066677Deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like. (422 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (474 aa)
ENSSSAP00000068802annotation not available (86 aa)
ACTR3-2Actin-related protein 3-like. (446 aa)
Mre11MRE11 homolog, double strand break repair nuclease. (452 aa)
timelessProtein timeless homolog. (1252 aa)
LOC106561926DNA damage-binding protein 1-like isoform X1. (1139 aa)
WRAP53Telomerase Cajal body protein 1-like. (731 aa)
LOC106562928Transitional endoplasmic reticulum ATPase-like. (834 aa)
LOC106574434Actin-related protein 3-like; Belongs to the actin family. (428 aa)
LOC106580289Transitional endoplasmic reticulum ATPase-like; Belongs to the AAA ATPase family. (711 aa)
LOC106571328E3 UFM1-protein ligase 1-like isoform X1. (794 aa)
LOC106564849Actin-related protein 2-A. (398 aa)
LOC106586392Telomere-associated protein RIF1-like. (2568 aa)
LOC106583204Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (204 aa)
LOC106611702pre-mRNA-processing factor 19-like. (505 aa)
ENSSSAP00000085304annotation not available (218 aa)
fam35aProtein FAM35A isoform X1. (564 aa)
aplfAprataxin and PNK-like factor isoform X1. (356 aa)
rpa3Replication protein A3. (159 aa)
LOC106613810Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (442 aa)
LOC106590210DNA endonuclease RBBP8-like. (723 aa)
LOC106580664E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] (557 aa)
LOC106570310Replication protein A 14 kDa subunit-like. (147 aa)
ddb1Salmo salar DNA damage-binding protein 1 (ddb1), mRNA. (1244 aa)
LOC106585012Transitional endoplasmic reticulum ATPase-like; Belongs to the AAA ATPase family. (819 aa)
ENSSSAP00000101078annotation not available (498 aa)
LOC106580672E3 ubiquitin-protein ligase RNF169-like. (544 aa)
ENSSSAP00000101867annotation not available (110 aa)
rad50DNA repair protein RAD50. (1316 aa)
smchd1Structural maintenance of chromosomes flexible hinge domain-containing protein 1 isoform X2. (2015 aa)
LOC106589757Protein FAM178A-like isoform X3. (629 aa)
smarcad1annotation not available (1005 aa)
LOC106575630Actin-related protein 2/3 complex subunit 2. (368 aa)
samhd1Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X2. (713 aa)
LOC106565748Histone-lysine N-methyltransferase SETMAR-like. (304 aa)
polhDNA polymerase eta. (782 aa)
ENSSSAP00000111484SET domain and mariner transposase fusion gene. (283 aa)
prp19Pre-mRNA-processing factor 19. (505 aa)
ENSSSAP00000114968annotation not available (273 aa)
LOC106565815Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
LOC106590428Actin-related protein 3B-like; Belongs to the actin family. (435 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (361 aa)
rnf138E3 ubiquitin-protein ligase RNF138. (271 aa)
LOC106582342Telomere-associated protein RIF1-like isoform X12. (2366 aa)
sirt6NAD-dependent protein deacetylase sirtuin-6 isoform X1. (383 aa)
rad18E3 ubiquitin-protein ligase RAD18 isoform X2. (501 aa)
LOC106565577Poly [ADP-ribose] polymerase. (532 aa)
LOC106563156Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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