(77 nodes) Positive regulation of endocytosis network (Salmo salar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cln3	Battenin. (440 aa)
	eef2k	Eukaryotic elongation factor 2 kinase. (746 aa)
	pick1	Salmo salar PRKCA-binding protein (pick1), mRNA. (440 aa)
	LOC106576553	Cell division control protein 42 homolog. (191 aa)
	LOC106579967	Low density lipoprotein receptor adapter protein 1-B-like isoform X1. (323 aa)
	ENSSSAP00000010379	annotation not available (108 aa)
	GREM1	Gremlin. (183 aa)
	LOC106609395	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2-like isoform X1. (2123 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (612 aa)
	appl1	DCC-interacting protein 13-alpha isoform X2. (722 aa)
	LOC106576364	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2-like. (1086 aa)
	LOC106576429	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2-like. (155 aa)
	lrrk2	Leucine-rich repeat serine/threonine-protein kinase 2 isoform X2. (2564 aa)
	LOC106576238	E3 ubiquitin-protein ligase Hakai-like isoform X2. (490 aa)
	LOC106603930	Rabankyrin-5-like isoform X2. (1191 aa)
	hakai	E3 ubiquitin-protein ligase Hakai. (485 aa)
	LOC106576457	SCY1-like protein 2. (291 aa)
	LOC106564688	Neuron-specific protein family member 1-like isoform X1. (203 aa)
	LOC106612042	Glypican-3-like; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (393 aa)
	LOC106567263	Cell division control protein 42 homolog isoform X2. (191 aa)
	APPL2	DCC-interacting protein 13-beta-like. (671 aa)
	LOC106560723	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2-like isoform X2. (218 aa)
	tsg101	Tumor susceptibility gene 101 protein. (404 aa)
	LOC106609531	Anoctamin. (920 aa)
	LOC106576394	Anoctamin. (920 aa)
	ankfy1	Rabankyrin-5 isoform X1. (1191 aa)
	LOC106567183	Tetraspanin. (241 aa)
	SERPINE1	Plasminogen activator inhibitor 1-like; Belongs to the serpin family. (391 aa)
	GREM1-2	Gremlin-1-like. (168 aa)
	cd63	Tetraspanin. (241 aa)
	LOC106602848	Vitronectin-like. (469 aa)
	tbc1d5	TBC1 domain family member 5 isoform X1. (884 aa)
	ahi1	Jouberin isoform X1. (1273 aa)
	LOC106570538	TBC1 domain family member 5-like. (819 aa)
	GREM1-3	Gremlin-1-like. (255 aa)
	LOC106588905	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (223 aa)
	LOC106570696	Low density lipoprotein receptor adapter protein 1-A-like isoform X1. (313 aa)
	LOC106581031	Vitronectin-like. (666 aa)
	ENSSSAP00000059439	annotation not available (460 aa)
	LOC106589068	Low density lipoprotein receptor adapter protein 1-A-like isoform X1. (324 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	dab2	Disabled homolog 2 isoform X1. (808 aa)
	scyl2	SCY1-like protein 2 isoform X1. (923 aa)
	vps28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (223 aa)
	LOC106560977	DCC-interacting protein 13-beta-like. (665 aa)
	LOC106565619	Cell division control protein 42 homolog isoform X1. (191 aa)
	LOC106604676	Signal-transducing adaptor protein 1-like. (341 aa)
	LOC106604959	Fragile X mental retardation protein 1 homolog B-like isoform X2. (599 aa)
	LOC106611992	Fragile X mental retardation protein 1 homolog A-like isoform X4. (593 aa)
	LOC106576553-2	Cell division control protein 42 homolog. (269 aa)
	LOC106570032	Palmitoyl-protein thioesterase 1-like. (328 aa)
	LOC106572399	Cell division control protein 42 homolog isoform X1. (191 aa)
	ENSSSAP00000073178	annotation not available (115 aa)
	arhb	Low density lipoprotein receptor adapter protein 1-B isoform X1. (409 aa)
	LOC106573044	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2-like isoform X3. (1406 aa)
	LOC106571724	Vascular endothelial growth factor A-like; Belongs to the PDGF/VEGF growth factor family. (170 aa)
	LOC106608947	Plasminogen activator inhibitor 1-like; Belongs to the serpin family. (388 aa)
	LOC106607154	PRKCA-binding protein-like. (715 aa)
	LOC106607816	Clusterin; Belongs to the clusterin family. (473 aa)
	clus	Clusterin; Belongs to the clusterin family. (504 aa)
	LOC106588426	Cell division control protein 42 homolog isoform X1. (206 aa)
	CCL19	C-C motif chemokine. (122 aa)
	GREM1-4	Gremlin-1-like. (181 aa)
	LOC106570861	C-C motif chemokine. (124 aa)
	clul1	Clusterin; Belongs to the clusterin family. (517 aa)
	LOC106582615	DCC-interacting protein 13-alpha-like isoform X2. (837 aa)
	LOC106569986	Cell division control protein 42 homolog. (191 aa)
	LOC106611793	Signal-transducing adaptor protein 1-like. (391 aa)
	ptpn5	Tyrosine-protein phosphatase non-receptor type 5 isoform X1. (574 aa)
	LOC106586869	Neuron-specific protein family member 1-like. (203 aa)
	dab2-2	Disabled homolog 2 isoform X1. (794 aa)
	LOC106583122	Cell division control protein 42 homolog isoform X1. (191 aa)
	LOC106609367	E3 ubiquitin-protein ligase Hakai-like. (519 aa)
	LOC106570128	Apolipoprotein Eb-like. (270 aa)
	LOC106588481	Palmitoyl-protein thioesterase 1-like. (324 aa)
	CAV3-2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	LOC106589523	Eukaryotic elongation factor 2 kinase-like isoform X1. (786 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APPL2	LOC106560977	ENSSSAP00000031002	ENSSSAP00000064851	DCC-interacting protein 13-beta-like.	DCC-interacting protein 13-beta-like.	0.999
APPL2	LOC106570696	ENSSSAP00000031002	ENSSSAP00000049199	DCC-interacting protein 13-beta-like.	Low density lipoprotein receptor adapter protein 1-A-like isoform X1.	0.676
APPL2	LOC106579967	ENSSSAP00000031002	ENSSSAP00000007557	DCC-interacting protein 13-beta-like.	Low density lipoprotein receptor adapter protein 1-B-like isoform X1.	0.676
APPL2	LOC106582615	ENSSSAP00000031002	ENSSSAP00000099218	DCC-interacting protein 13-beta-like.	DCC-interacting protein 13-alpha-like isoform X2.	0.999
APPL2	LOC106589068	ENSSSAP00000031002	ENSSSAP00000059652	DCC-interacting protein 13-beta-like.	Low density lipoprotein receptor adapter protein 1-A-like isoform X1.	0.676
APPL2	LOC106603930	ENSSSAP00000031002	ENSSSAP00000023603	DCC-interacting protein 13-beta-like.	Rabankyrin-5-like isoform X2.	0.614
APPL2	ankfy1	ENSSSAP00000031002	ENSSSAP00000038628	DCC-interacting protein 13-beta-like.	Rabankyrin-5 isoform X1.	0.614
APPL2	appl1	ENSSSAP00000031002	ENSSSAP00000014901	DCC-interacting protein 13-beta-like.	DCC-interacting protein 13-alpha isoform X2.	0.999
APPL2	arhb	ENSSSAP00000031002	ENSSSAP00000074033	DCC-interacting protein 13-beta-like.	Low density lipoprotein receptor adapter protein 1-B isoform X1.	0.676
ENSSSAP00000010379	LOC106567183	ENSSSAP00000010379	ENSSSAP00000039190	annotation not available	Tetraspanin.	0.601
ENSSSAP00000010379	LOC106588905	ENSSSAP00000010379	ENSSSAP00000046116	annotation not available	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.990
ENSSSAP00000010379	cd63	ENSSSAP00000010379	ENSSSAP00000040997	annotation not available	Tetraspanin.	0.594
ENSSSAP00000010379	vps28	ENSSSAP00000010379	ENSSSAP00000064661	annotation not available	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.990
LOC106560977	APPL2	ENSSSAP00000064851	ENSSSAP00000031002	DCC-interacting protein 13-beta-like.	DCC-interacting protein 13-beta-like.	0.999
LOC106560977	LOC106570696	ENSSSAP00000064851	ENSSSAP00000049199	DCC-interacting protein 13-beta-like.	Low density lipoprotein receptor adapter protein 1-A-like isoform X1.	0.676
LOC106560977	LOC106579967	ENSSSAP00000064851	ENSSSAP00000007557	DCC-interacting protein 13-beta-like.	Low density lipoprotein receptor adapter protein 1-B-like isoform X1.	0.676
LOC106560977	LOC106582615	ENSSSAP00000064851	ENSSSAP00000099218	DCC-interacting protein 13-beta-like.	DCC-interacting protein 13-alpha-like isoform X2.	0.999
LOC106560977	LOC106589068	ENSSSAP00000064851	ENSSSAP00000059652	DCC-interacting protein 13-beta-like.	Low density lipoprotein receptor adapter protein 1-A-like isoform X1.	0.676
LOC106560977	LOC106603930	ENSSSAP00000064851	ENSSSAP00000023603	DCC-interacting protein 13-beta-like.	Rabankyrin-5-like isoform X2.	0.614
LOC106560977	ankfy1	ENSSSAP00000064851	ENSSSAP00000038628	DCC-interacting protein 13-beta-like.	Rabankyrin-5 isoform X1.	0.614