(35 nodes) Negative regulation of mRNA splicing, via spliceosome network (Salmo salar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106567406	Complement component 1 Q subcomponent-binding protein, mitochondrial-like isoform X2. (372 aa)
	LOC106577794	Apoptotic chromatin condensation inducer in the nucleus-like isoform X1. (1485 aa)
	LOC106612606	Serine/arginine-rich splicing factor 7-like isoform X1. (200 aa)
	LOC106575588	Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (156 aa)
	LOC106588451	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (472 aa)
	sfswap	Splicing factor, suppressor of white-apricot homolog isoform X1. (1022 aa)
	LOC106584788	Serine/arginine-rich splicing factor 7-like isoform X3. (261 aa)
	LOC106601453	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (481 aa)
	ENSSSAP00000003612	annotation not available (137 aa)
	ENSSSAP00000003619	annotation not available (303 aa)
	LOC106580853	Serine/arginine-rich splicing factor 7-like isoform X3. (223 aa)
	sfrs9	Splicing factor, arginine/serine-rich 9 isoform X1. (258 aa)
	RBM20	RNA-binding protein 20-like. (1259 aa)
	u2af2	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (480 aa)
	LOC106572208	Nuclease-sensitive element-binding protein 1-like isoform X1. (379 aa)
	u2af2-2	Splicing factor U2AF 65 kDa subunit-like. (480 aa)
	LOC106608850	Apoptotic chromatin condensation inducer in the nucleus-like isoform X1. (1608 aa)
	LOC106567629	Serine/arginine-rich splicing factor 7-like. (256 aa)
	ENSSSAP00000023604	annotation not available (465 aa)
	RBM20-2	RNA-binding protein 20-like isoform X1. (1247 aa)
	acin1	Apoptotic chromatin condensation inducer in the nucleus. (1695 aa)
	LOC106563159	Splicing factor, suppressor of white-apricot homolog isoform X1. (983 aa)
	LOC106568192	Serine/arginine-rich splicing factor 9-like. (249 aa)
	LOC106603944	Complement component 1 Q subcomponent-binding protein, mitochondrial-like. (289 aa)
	LOC106611724	RNA-binding motif protein, X chromosome-like isoform X1. (377 aa)
	ENSSSAP00000070692	annotation not available (127 aa)
	YBX1	Y-box binding protein-2 isoform X2. (322 aa)
	u2af2-3	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (474 aa)
	LOC106600278	Apoptotic chromatin condensation inducer in the nucleus-like. (2058 aa)
	srsf7	Serine/arginine-rich splicing factor 7 isoform X2. (238 aa)
	LOC106603690	Serine/arginine-rich splicing factor 7-like isoform X1. (266 aa)
	LOC106611619	Nucleophosmin-like. (322 aa)
	srsf9	Serine/arginine-rich splicing factor 9. (258 aa)
	hnrpg	Heterogeneous nuclear ribonucleoprotein G isoform X2. (385 aa)
	sap18	Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (156 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSSAP00000003612	ENSSSAP00000003619	ENSSSAP00000003612	ENSSSAP00000003619	annotation not available	annotation not available	0.486
ENSSSAP00000003612	LOC106567629	ENSSSAP00000003612	ENSSSAP00000022973	annotation not available	Serine/arginine-rich splicing factor 7-like.	0.632
ENSSSAP00000003612	LOC106568192	ENSSSAP00000003612	ENSSSAP00000116070	annotation not available	Serine/arginine-rich splicing factor 9-like.	0.744
ENSSSAP00000003612	LOC106580853	ENSSSAP00000003612	ENSSSAP00000059214	annotation not available	Serine/arginine-rich splicing factor 7-like isoform X3.	0.632
ENSSSAP00000003612	LOC106584788	ENSSSAP00000003612	ENSSSAP00000002035	annotation not available	Serine/arginine-rich splicing factor 7-like isoform X3.	0.632
ENSSSAP00000003612	LOC106603690	ENSSSAP00000003612	ENSSSAP00000097446	annotation not available	Serine/arginine-rich splicing factor 7-like isoform X1.	0.632
ENSSSAP00000003612	LOC106611724	ENSSSAP00000003612	ENSSSAP00000070464	annotation not available	RNA-binding motif protein, X chromosome-like isoform X1.	0.414
ENSSSAP00000003612	LOC106612606	ENSSSAP00000003612	ENSSSAP00000043866	annotation not available	Serine/arginine-rich splicing factor 7-like isoform X1.	0.632
ENSSSAP00000003612	hnrpg	ENSSSAP00000003612	ENSSSAP00000106676	annotation not available	Heterogeneous nuclear ribonucleoprotein G isoform X2.	0.414
ENSSSAP00000003612	sfrs9	ENSSSAP00000003612	ENSSSAP00000009108	annotation not available	Splicing factor, arginine/serine-rich 9 isoform X1.	0.744
ENSSSAP00000003612	srsf7	ENSSSAP00000003612	ENSSSAP00000088966	annotation not available	Serine/arginine-rich splicing factor 7 isoform X2.	0.632
ENSSSAP00000003612	srsf9	ENSSSAP00000003612	ENSSSAP00000104386	annotation not available	Serine/arginine-rich splicing factor 9.	0.744
ENSSSAP00000003619	ENSSSAP00000003612	ENSSSAP00000003619	ENSSSAP00000003612	annotation not available	annotation not available	0.486
ENSSSAP00000003619	LOC106567629	ENSSSAP00000003619	ENSSSAP00000022973	annotation not available	Serine/arginine-rich splicing factor 7-like.	0.632
ENSSSAP00000003619	LOC106568192	ENSSSAP00000003619	ENSSSAP00000116070	annotation not available	Serine/arginine-rich splicing factor 9-like.	0.744
ENSSSAP00000003619	LOC106580853	ENSSSAP00000003619	ENSSSAP00000059214	annotation not available	Serine/arginine-rich splicing factor 7-like isoform X3.	0.632
ENSSSAP00000003619	LOC106584788	ENSSSAP00000003619	ENSSSAP00000002035	annotation not available	Serine/arginine-rich splicing factor 7-like isoform X3.	0.632
ENSSSAP00000003619	LOC106603690	ENSSSAP00000003619	ENSSSAP00000097446	annotation not available	Serine/arginine-rich splicing factor 7-like isoform X1.	0.632
ENSSSAP00000003619	LOC106611724	ENSSSAP00000003619	ENSSSAP00000070464	annotation not available	RNA-binding motif protein, X chromosome-like isoform X1.	0.414
ENSSSAP00000003619	LOC106612606	ENSSSAP00000003619	ENSSSAP00000043866	annotation not available	Serine/arginine-rich splicing factor 7-like isoform X1.	0.632