(62 nodes) Positive regulation of peptide hormone secretion network (Salmo salar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106569042	Corticoliberin-1-like isoform X1. (233 aa)
	pla2g6	85/88 kDa calcium-independent phospholipase A2 isoform X1. (831 aa)
	ENSSSAP00000008355	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1. (295 aa)
	ENSSSAP00000008891	annotation not available (143 aa)
	LOC106570251	Nuclear receptor subfamily 0 group B member 2-like. (289 aa)
	LOC106611404	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1057 aa)
	ENSSSAP00000010059	annotation not available (121 aa)
	LOC106573302	Bile acid receptor-like isoform X1. (487 aa)
	LOC106574970	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (135 aa)
	LOC106576415	Transmembrane 7 superfamily member 3-like. (561 aa)
	pdx1	Pancreas/duodenum homeobox protein 1. (276 aa)
	LOC106564381	85/88 kDa calcium-independent phospholipase A2-like. (534 aa)
	LOC106609510	Transmembrane 7 superfamily member 3-like isoform X1. (592 aa)
	LOC106595137	Immunoglobulin-like domain-containing receptor 1 isoform X1. (327 aa)
	mcu	Calcium uniporter protein, mitochondrial. (319 aa)
	ENSSSAP00000023740	annotation not available (151 aa)
	LOC106575789	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (147 aa)
	nr1h4	Bile acid receptor. (580 aa)
	LOC106605079	Nuclear receptor subfamily 0 group B member 2-like. (257 aa)
	LOC106568916	Rab effector MyRIP-like isoform X2. (1547 aa)
	LOC106590856	Fibrinogen beta chain-like isoform X2. (489 aa)
	LOC106607790	DNA-binding protein RFX6-like. (896 aa)
	adcy8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1221 aa)
	LOC106578087	Bcl2-associated agonist of cell death-like. (158 aa)
	LOC106571539	DNA-binding protein RFX6-like. (850 aa)
	LOC106578170	Fibrinogen beta chain-like. (492 aa)
	LOC106588612	Nuclear receptor subfamily 0 group B member 2-like. (288 aa)
	LOC106578225	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1-like. (327 aa)
	ghrl	Preproghrelin-2 precursor. (108 aa)
	LOC106566843	Bile acid receptor-like isoform X1. (492 aa)
	MCUB	Calcium uniporter protein, mitochondrial-like isoform X1. (365 aa)
	LOC106610343	Calcium uniporter protein, mitochondrial-like. (444 aa)
	aimp1	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 isoform X1. (355 aa)
	LOC106579547	Corticoliberin-1-like. (167 aa)
	tnfsf11	Tumor necrosis factor ligand superfamily member 11 isoform X1; Belongs to the tumor necrosis factor family. (284 aa)
	c2cd2l	C2 domain-containing protein 2-like isoform X2. (710 aa)
	LOC106582173	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family. (270 aa)
	LOC106592211	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family. (261 aa)
	LOC106561422	Bile acid receptor-like isoform X1. (492 aa)
	sri	Sorcin. (228 aa)
	LOC106590452	Pancreas/duodenum homeobox protein 1-like. (255 aa)
	capn10	Calpain-10; Belongs to the peptidase C2 family. (676 aa)
	LOC106586746	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (129 aa)
	LOC106588240	Free fatty acid receptor 2-like. (329 aa)
	ENSSSAP00000085883	annotation not available (242 aa)
	LOC106575298	Grancalcin-like. (222 aa)
	LOC106582173-2	Tumor necrosis factor ligand superfamily member 11-like. (270 aa)
	ucn	Urocortin. (165 aa)
	LOC106571442	UI-like. (199 aa)
	Psmd9	26S proteasome regulatory subunit N4. (171 aa)
	psmd9	26S proteasome non-ATPase regulatory subunit 9. (212 aa)
	aacs	acetoacetyl-CoA synthetase. (673 aa)
	nr0b2	Nuclear receptor subfamily 0 group B member 2. (256 aa)
	LOC106575455	Tumor necrosis factor ligand superfamily member 11-like; Belongs to the tumor necrosis factor family. (261 aa)
	LOC106571889	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (256 aa)
	crf1	Corticoliberin-1 isoform X1. (170 aa)
	trh	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (258 aa)
	LOC106590856-2	Fibrinogen beta chain-like. (489 aa)
	gran	Grancalcin. (222 aa)
	ENSSSAP00000114968	annotation not available (273 aa)
	LOC106590389	Corticoliberin-1-like. (167 aa)
	sirt6	NAD-dependent protein deacetylase sirtuin-6 isoform X1. (383 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSSAP00000114968	aacs	ENSSSAP00000114968	ENSSSAP00000105519	annotation not available	acetoacetyl-CoA synthetase.	0.413
LOC106561422	LOC106570251	ENSSSAP00000062630	ENSSSAP00000009661	Bile acid receptor-like isoform X1.	Nuclear receptor subfamily 0 group B member 2-like.	0.520
LOC106561422	LOC106588612	ENSSSAP00000062630	ENSSSAP00000040367	Bile acid receptor-like isoform X1.	Nuclear receptor subfamily 0 group B member 2-like.	0.520
LOC106561422	LOC106605079	ENSSSAP00000062630	ENSSSAP00000029362	Bile acid receptor-like isoform X1.	Nuclear receptor subfamily 0 group B member 2-like.	0.747
LOC106561422	nr0b2	ENSSSAP00000062630	ENSSSAP00000106841	Bile acid receptor-like isoform X1.	Nuclear receptor subfamily 0 group B member 2.	0.520
LOC106566843	LOC106570251	ENSSSAP00000043778	ENSSSAP00000009661	Bile acid receptor-like isoform X1.	Nuclear receptor subfamily 0 group B member 2-like.	0.520
LOC106566843	LOC106588612	ENSSSAP00000043778	ENSSSAP00000040367	Bile acid receptor-like isoform X1.	Nuclear receptor subfamily 0 group B member 2-like.	0.520
LOC106566843	LOC106605079	ENSSSAP00000043778	ENSSSAP00000029362	Bile acid receptor-like isoform X1.	Nuclear receptor subfamily 0 group B member 2-like.	0.520
LOC106566843	nr0b2	ENSSSAP00000043778	ENSSSAP00000106841	Bile acid receptor-like isoform X1.	Nuclear receptor subfamily 0 group B member 2.	0.520
LOC106569042	LOC106571442	ENSSSAP00000086089	ENSSSAP00000099374	Corticoliberin-1-like isoform X1.	UI-like.	0.937
LOC106569042	LOC106571889	ENSSSAP00000086089	ENSSSAP00000110085	Corticoliberin-1-like isoform X1.	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.	0.757
LOC106569042	LOC106579547	ENSSSAP00000086089	ENSSSAP00000052879	Corticoliberin-1-like isoform X1.	Corticoliberin-1-like.	0.902
LOC106569042	LOC106590389	ENSSSAP00000086089	ENSSSAP00000118276	Corticoliberin-1-like isoform X1.	Corticoliberin-1-like.	0.903
LOC106569042	crf1	ENSSSAP00000086089	ENSSSAP00000113328	Corticoliberin-1-like isoform X1.	Corticoliberin-1 isoform X1.	0.901
LOC106569042	ghrl	ENSSSAP00000086089	ENSSSAP00000042961	Corticoliberin-1-like isoform X1.	Preproghrelin-2 precursor.	0.642
LOC106569042	trh	ENSSSAP00000086089	ENSSSAP00000113536	Corticoliberin-1-like isoform X1.	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.	0.732
LOC106569042	ucn	ENSSSAP00000086089	ENSSSAP00000098781	Corticoliberin-1-like isoform X1.	Urocortin.	0.931
LOC106570251	LOC106561422	ENSSSAP00000009661	ENSSSAP00000062630	Nuclear receptor subfamily 0 group B member 2-like.	Bile acid receptor-like isoform X1.	0.520
LOC106570251	LOC106566843	ENSSSAP00000009661	ENSSSAP00000043778	Nuclear receptor subfamily 0 group B member 2-like.	Bile acid receptor-like isoform X1.	0.520
LOC106570251	LOC106573302	ENSSSAP00000009661	ENSSSAP00000013765	Nuclear receptor subfamily 0 group B member 2-like.	Bile acid receptor-like isoform X1.	0.520