50 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FGF4-2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
	SIX3	Homeobox protein SIX3-like. (294 aa)
	LOC106606173	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (582 aa)
	LOC106593771	Exocyst complex component 5. (712 aa)
	FGF4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
	LOC106563612	Probetacellulin-like. (188 aa)
	exoc5	Exocyst complex component 5. (710 aa)
	arf6	ADP-ribosylation factor 6-like; Belongs to the small GTPase superfamily. Arf family. (176 aa)
	six3	Homeobox protein SIX3. (294 aa)
	pdx1	Pancreas/duodenum homeobox protein 1. (276 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (444 aa)
	LOC106601126	Apoptosis regulator BAX-like. (225 aa)
	ENSSSAP00000029885	CD248 molecule, endosialin a. (699 aa)
	LOC106608083	ADP-ribosylation factor 6-like; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	LOC106578207	Endothelin-1 receptor-like. (222 aa)
	LOC106612166	Homeobox protein Nkx-2.5-like. (315 aa)
	LOC106608888	Homeobox protein SIX6-like isoform X1. (266 aa)
	LOC106610306	Caspase-6-like isoform X1; Belongs to the peptidase C14A family. (301 aa)
	ENSSSAP00000046409	DNA (cytosine-5)-methyltransferase 3A-like. (146 aa)
	CASP6	Caspase-6-like isoform X1; Belongs to the peptidase C14A family. (321 aa)
	LOC106611457	Protein salvador homolog 1-like. (417 aa)
	LOC106587136	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (191 aa)
	sav1	Protein salvador homolog 1 isoform X1. (423 aa)
	LOC106594345	Bone morphogenetic protein receptor type-2-like. (698 aa)
	LOC106577861	Homeobox protein SIX6-like isoform X1. (266 aa)
	LOC106590452	Pancreas/duodenum homeobox protein 1-like. (255 aa)
	ENSSSAP00000067973	TATA element modulatory factor 1. (1065 aa)
	LOC106593270	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (632 aa)
	LOC106563689	Endosialin-like. (694 aa)
	LOC106607328	Apoptosis regulator BAX-like. (194 aa)
	ENSSSAP00000073552	annotation not available (175 aa)
	LOC106566901	Transcription factor E2F1-like. (433 aa)
	LOC106571580	ADP-ribosylation factor 6. (175 aa)
	LOC106578932	Homeobox protein SIX3-like isoform X1. (265 aa)
	tgfr2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (549 aa)
	ENSSSAP00000092715	CD248 antigen, endosialin. (545 aa)
	LOC106568957	Angiopoietin-related protein 4-like. (462 aa)
	LOC106568258	Probetacellulin-like. (189 aa)
	casp9	Caspase-9 isoform X1; Belongs to the peptidase C14A family. (450 aa)
	LOC106567147	Caspase-9-like; Belongs to the peptidase C14A family. (456 aa)
	LOC106610223	Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family. (481 aa)
	angl4	Angiopoietin-related protein 4 precursor. (490 aa)
	LOC106604305	Homeobox protein Nkx-2.5-like. (315 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (571 aa)
	LOC106572360	Transcription factor E2F1-like isoform X2. (444 aa)
	LOC106577513	Endosialin-like. (718 aa)
	tmf1	TATA element modulatory factor isoform X1. (1170 aa)
	rb1	Retinoblastoma-associated protein. (910 aa)
	LOC106561974	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (191 aa)
	ENSSSAP00000120352	Fibroblast growth factor 9. (184 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP6	LOC106567147	ENSSSAP00000048919	ENSSSAP00000099548	Caspase-6-like isoform X1; Belongs to the peptidase C14A family.	Caspase-9-like; Belongs to the peptidase C14A family.	0.966
CASP6	LOC106601126	ENSSSAP00000048919	ENSSSAP00000025308	Caspase-6-like isoform X1; Belongs to the peptidase C14A family.	Apoptosis regulator BAX-like.	0.429
CASP6	LOC106607328	ENSSSAP00000048919	ENSSSAP00000073537	Caspase-6-like isoform X1; Belongs to the peptidase C14A family.	Apoptosis regulator BAX-like.	0.429
CASP6	LOC106610306	ENSSSAP00000048919	ENSSSAP00000044361	Caspase-6-like isoform X1; Belongs to the peptidase C14A family.	Caspase-6-like isoform X1; Belongs to the peptidase C14A family.	0.900
CASP6	casp9	ENSSSAP00000048919	ENSSSAP00000098797	Caspase-6-like isoform X1; Belongs to the peptidase C14A family.	Caspase-9 isoform X1; Belongs to the peptidase C14A family.	0.966
ENSSSAP00000046409	rb1	ENSSSAP00000046409	ENSSSAP00000113901	DNA (cytosine-5)-methyltransferase 3A-like.	Retinoblastoma-associated protein.	0.401
ENSSSAP00000073552	LOC106567147	ENSSSAP00000073552	ENSSSAP00000099548	annotation not available	Caspase-9-like; Belongs to the peptidase C14A family.	0.470
ENSSSAP00000073552	casp9	ENSSSAP00000073552	ENSSSAP00000098797	annotation not available	Caspase-9 isoform X1; Belongs to the peptidase C14A family.	0.470
LOC106563612	LOC106568258	ENSSSAP00000013964	ENSSSAP00000094840	Probetacellulin-like.	Probetacellulin-like.	0.901
LOC106566901	rb1	ENSSSAP00000075532	ENSSSAP00000113901	Transcription factor E2F1-like.	Retinoblastoma-associated protein.	0.999
LOC106567147	CASP6	ENSSSAP00000099548	ENSSSAP00000048919	Caspase-9-like; Belongs to the peptidase C14A family.	Caspase-6-like isoform X1; Belongs to the peptidase C14A family.	0.966
LOC106567147	ENSSSAP00000073552	ENSSSAP00000099548	ENSSSAP00000073552	Caspase-9-like; Belongs to the peptidase C14A family.	annotation not available	0.470
LOC106567147	LOC106601126	ENSSSAP00000099548	ENSSSAP00000025308	Caspase-9-like; Belongs to the peptidase C14A family.	Apoptosis regulator BAX-like.	0.470
LOC106567147	LOC106607328	ENSSSAP00000099548	ENSSSAP00000073537	Caspase-9-like; Belongs to the peptidase C14A family.	Apoptosis regulator BAX-like.	0.470
LOC106567147	LOC106610306	ENSSSAP00000099548	ENSSSAP00000044361	Caspase-9-like; Belongs to the peptidase C14A family.	Caspase-6-like isoform X1; Belongs to the peptidase C14A family.	0.963
LOC106567147	casp9	ENSSSAP00000099548	ENSSSAP00000098797	Caspase-9-like; Belongs to the peptidase C14A family.	Caspase-9 isoform X1; Belongs to the peptidase C14A family.	0.900
LOC106568258	LOC106563612	ENSSSAP00000094840	ENSSSAP00000013964	Probetacellulin-like.	Probetacellulin-like.	0.901
LOC106571580	LOC106593771	ENSSSAP00000080143	ENSSSAP00000011470	ADP-ribosylation factor 6.	Exocyst complex component 5.	0.624
LOC106571580	exoc5	ENSSSAP00000080143	ENSSSAP00000016876	ADP-ribosylation factor 6.	Exocyst complex component 5.	0.624
LOC106572360	rb1	ENSSSAP00000110535	ENSSSAP00000113901	Transcription factor E2F1-like isoform X2.	Retinoblastoma-associated protein.	0.995